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  1. 1981
    “…For low RH, the SOA mass formed was up to 30% of the initial OA, accompanied by a moderate change in both O : C levels (7–8% increase) and the OA spectrum. …”
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    Characterization and dark oxidation of the emissions of a pellet stove
  2. 1982
    “…The pathophysiology of osteoarthritis (OA) involves the destruction of articular cartilage and the overgrowth of bone with lipping and spur formation. …”
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    Non-steroidal Anti-inflammatory Drugs and Osteopathic Manipulative Treatment for Pain Management in Patients With Osteoarthritis: A Literature Review
  3. 1983
    “…Females showing OA without family history were regarded as representing autosomal recessive OA (OA3). …”
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    Screening of TYR, OCA2, GPR143, and MC1R in patients with congenital nystagmus, macular hypoplasia, and fundus hypopigmentation indicating albinism
  4. 1984
    “…BACKGROUND: Oxidative stress play a main role in the initiation and progression of the OA disease and leads to the degeneration of mitochondria. …”
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    Mitochondrial DNA (mtDNA) haplogroups and serum levels of anti-oxidant enzymes in patients with osteoarthritis
  5. 1985
    “…To investigate in the general population the clinical impact of erosive OA in interphalangeal joints (IPJs) compared with symptomatic radiographic hand OA and inflammatory arthritis. …”
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    Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies
  6. 1986
    “…Osteoarthritis (OA) of the joint is a prevalent disease accompanied by chronic, debilitating pain. …”
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    Cannabinoid CB(2) Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint
  7. 1987
    “…Intriguingly, OA of the left knee prolonged RT and MT to the same degree as OA on the contralateral side (RT p = 0.001, MT p < 0.001). …”
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    Osteoarthritis of the knee or hip significantly impairs driving ability (cross-sectional survey)
  8. 1988
    por Vennu, Vishal, Bindawas, Saad M
    Publicado 2014
    “…BACKGROUND: The purpose of this study was to examine the relationship between self-reported falls, doctor-diagnosed knee osteoarthritis (OA), and health-related quality of life (HRQoL). …”
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    Relationship between falls, knee osteoarthritis, and health-related quality of life: data from the Osteoarthritis Initiative study
  9. 1989
    “…Cases had clinically severe symptoms and radiographic knee or hip OA; controls had no symptoms and no radiographic knee/hip OA. …”
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    Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis
  10. 1990
    “…OBJECTIVES: Nerve growth factor (NGF) is a promising analgesic target, particularly in osteoarthritis (OA) where existing therapies are inadequate. We hypothesised that pain responses to NGF are increased in OA joints. …”
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    Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis
  11. 1991
    “…INTRODUCTION: Few data are available concerning structural changes at the hip observed by magnetic resonance imaging (MRI) in people with or without hip osteoarthritis (OA). The aim of this study was to compare cartilage volume and the presence of cartilage defects and bone marrow lesions (BMLs) in participants with and without diagnosed hip OA. …”
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    Structural changes of hip osteoarthritis using magnetic resonance imaging
  12. 1992
    “…BACKGROUND: While the impact of knee pain and knee osteoarthritis (OA) on health-related quality of life (HRQoL) has been investigated in the literature, there is a lack of knowledge on the impact of different definitions of OA on HRQoL. …”
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    Association of knee pain and different definitions of knee osteoarthritis with health-related quality of life: a population-based cohort study in southern Sweden
  13. 1993
    “…BACKGROUND: Few data are available concerning intercondylar notch dimensions in female nonathletes with knee osteoarthritis (OA) in plateau region. The aim of this study was to assess the relation of intercondylar notch morphology to anterior cruciate ligament (ACL) injuries in female nonathletes with knee OA aged 41–65 years from the Chinese Loess Plateau. …”
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    Narrow Intercondylar Notch and Anterior Cruciate Ligament Injury in Female Nonathletes with Knee Osteoarthritis Aged 41–65 Years in Plateau Region
  14. 1994
    “…Additionally, intra-articular delivery of PGRN protects against osteoarthritis (OA) progression. The purpose of this study is to determine whether Atsttrin also has therapeutic effects in OA and the molecular mechanisms involved. …”
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    Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models
  15. 1995
    “…It was hypothesized that AQP1 may be highly expressed in OA cartilage and that it may increase the expression of catabolic factors during inflammatory OA progression. …”
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    Depletion of aquaporin 1 decreased ADAMTS-4 expression in human chondrocytes
  16. 1996
    “…INTRODUCTION: Osteoarthritis (OA) is a heterogeneous and complex disease. We have used a network biology approach based on genome-wide analysis of gene expression in OA knee cartilage to seek evidence for pathogenic mechanisms that may distinguish different patient subgroups. …”
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    Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage
  17. 1997
    “…Following the construction of an OA rabbit model, normal chondrocytes (normal control group), OA chondrocytes obtained 4 weeks after modeling (OA at week 4 group) and 8 weeks after modeling (OA at week 8 group) were used. …”
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    Abnormal expression of miR-4784 in chondrocytes of osteoarthritis and associations with chondrocyte hyperplasia
  18. 1998
    “…Osteoarthritis (OA) is a degenerative disease that induces pain, cartilage deformation, and joint inflammation. …”
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    The Therapeutic Effect of STAT3 Signaling-Suppressed MSC on Pain and Articular Cartilage Damage in a Rat Model of Monosodium Iodoacetate-Induced Osteoarthritis
  19. 1999
    “…BACKGROUND: We consider the relationships between a clinical and radiological diagnosis of knee or hip OA and activities of daily-living (ADL) in older adults. …”
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    Impact of osteoarthritis on activities of daily living: does joint site matter?
  20. 2000
    “…BACKGROUND: Osteoarthritis (OA) is the most common type of joint disease associated with cartilage breakdown. …”
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    p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis
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