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  1. 20541
    “…These genes belonged to a wide variety of categories, including those encoding the innate immune system proteins (APOBEC3G, OAS2, and CEACAM1) among others related to the immune response. …”
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    Transcriptome of the Southern Muriqui Brachyteles arachnoides (Primates:Platyrrhini), a Critically Endangered New World Monkey: Evidence of Adaptive Evolution
  2. 20542
    por He, Tingyan, Xia, Yu, Yang, Jun
    Publicado 2021
    “…Over-expression of IFN-stimulated cytokine genes was observed, including IFI44, IFI27, IFIT1, IFIT2, IFIT3, ISG15, OAS1, and SIGLEC1. CONCLUSIONS: To date, only two cases with AGS have been reported to have renal disease. …”
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    Systemic inflammation and chronic kidney disease in a patient due to the RNASEH2B defect
  3. 20543
    “…In addition, the activation of the LINE1 family of elements in IPF is associated with the increased expression of TE cellular regulators (MOV10, IFI16, SAMHD1, and APOBECG3), interferon-stimulating genes (ISG15, IFI6, IFI27, IFI44, and OAS1), chemokines (CX3CL1 and CXCL9), and interleukins (IL15RA). …”
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    The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis
  4. 20544
    “…The mRNA levels of 2′-5′-oligoadenylate synthetase like (OASL), myxovirus resistance 1 (MX1), 2′5′-oligoadenylate synthetase 1 (OAS1), interferon-stimulated gene 15 (ISG15) and lymphocyte antigen 6 complex, locus E (LY6E) were determined using real-time PCR. …”
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    Interferon Lambda 3/4 (IFNλ3/4) rs12979860 Polymorphisms Is Not Associated With Susceptibility to Systemic Lupus Erythematosus, Although It Regulates OASL Expression in Patients With SLE
  5. 20545
    “…Of those, the following distinct pathways were targeted by the dysregulation (compared with the non-diabetic control group): OAS1 increased by 111% (p < 1.00 × 10(−4), 95% CI −0.43, −0.15); MX1 increased by 142% (p < 1.00 × 10(−4), 95% CI −0.52, −0.22); and ISG15 increased by 197% (p = 2.00 × 10(−4), 95% CI −0.68, −0.18). …”
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    Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity
  6. 20546
    “…Specifically, infection of MAGI1-null ECs with IAV upregulates expression of signal transducer and activator of transcription 1 (STAT1), interferon b1 (IFNb1), myxovirus resistance protein 1 (MX1) and 2′-5′-oligoadenylate synthetase 2 (OAS2), and activate STAT5. By contrast, MAGI1 overexpression inhibits Ifnb1 mRNA and MX1 expression, again supporting the pro-viral response mediated by MAGI1. …”
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    MAGI1 inhibits interferon signaling to promote influenza A infection
  7. 20547
    “…Additionally, the higher expression of several genes, including AKT1, BST2, OAS3, or CD8B; or higher dendritic cells and neutrophils proportions in post-treatment non-CPR samples, were associated with relapse after surgery. …”
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    Tumor microenvironment gene expression profiles associated to complete pathological response and disease progression in resectable NSCLC patients treated with neoadjuvant chemoimmunotherapy
  8. 20548
    “…RESULTS: The median patient delay among OAS patients in this study was 22 months, the median provider delay was one month, and the median total delay was 26 months. …”
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    Factors influencing patient delay in individuals with obstructive sleep apnoea: a study based on an integrated model
  9. 20549
    “…At the same time we identified novel, highly suggestive loci for a variety of traits that did not meet genome-wide significant thresholds in prior analyses, in some cases with strong support from the primary medical genetics literature (SLC16A7, CSMD1, OAS1), suggesting these genes merit further study. …”
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    An Open Access Database of Genome-wide Association Results
  10. 20550
    “…PR8 virus increased ROS production, Nrf2, HO-1, Mx1 and OAS1 expression and Nrf2 translocation to the nucleus. …”
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    Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus
  11. 20551
    “…There were a significantly higher relapse and death rate and a lower rate of CR, DFS, and OAS in negative WT-1 gene expression group. MRD at end of induction therapy was found in 14 cases out of 40 patients. …”
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    Prognostic Impact of WT-1 Gene Expression in Egyptian Children with Acute Lymphoblastic Leukemia
  12. 20552
    “…ZIKV induced the transcription of various genes expressing pattern recognition receptors (TLR2, TLR3, and RIG-I), cytokines/chemokines (TNF-α, IL-1β, CCL5, and CXCL10), interferons (IFN-α2, IFN-β1, and IFN-γ), and interferon-stimulated genes (ISG15 and OAS2) in Pr. TM cells. ZIKV infection in IFNAR1(−/−) and wild-type (WT) mouse eyes resulted in increased intraocular pressure (IOP) and the development of chorioretinal atrophy. …”
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    Zika Virus Infects Trabecular Meshwork and Causes Trabeculitis and Glaucomatous Pathology in Mouse Eyes
  13. 20553
    “…RHIOB and WHIOB rapidly chemisorbed As(III) from water (∼24% removal in first half an hour reaching up to ∼100% removal in 24 h) at surface Fe–OH functions forming monodentate ≡Fe–OAs(OH)(2) and bidentate (≡Fe–O)(2)AsOH complexes. …”
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    Sustainable Low-Concentration Arsenite [As(III)] Removal in Single and Multicomponent Systems Using Hybrid Iron Oxide–Biochar Nanocomposite Adsorbents—A Mechanistic Study
  14. 20554
    por Park, Amber, Harris, Laura K.
    Publicado 2021
    “…Five positive icSARS panel genes, CXCL10, OAS3, OASL, IFIT3, and XAF1, are found across mice and human signatures regardless of SARS strains. …”
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    Gene Expression Meta-Analysis Reveals Interferon-Induced Genes Associated With SARS Infection in Lungs
  15. 20555
    “…Bioinformatics analysis identified 11 hub genes (LCK, IL2RG, CD3G, STAT1, CD247, IL2RB, CD3D, IRF1, OAS2, IRF4, and IFNG) related to the immune subtype. …”
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    A Machine Learning Model to Predict the Triple Negative Breast Cancer Immune Subtype
  16. 20556
    “…The mRNA levels of IRF3, ISGs including ISG15, OAS, PKR and immune factors including IFNγ, TNFα, TGFβ, IL-6, IL-10, PDL1 in liver of the mice were quantified by qRT-PCR. …”
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    The dose of HBV genome contained plasmid has a great impact on HBV persistence in hydrodynamic injection mouse model
  17. 20557
    “…Depressive symptoms (CES-D scores ≥ 16) were more prevalent in HIV+ tobacco smokers compared with HIV+ and HIV− non-smokers (50% vs. 26% and 13%, respectively; p = 0.007), and upregulation of immune/interferon response genes, including IFI35, IFNAR1, OAS1-2, STAT1, and SP100, was associated with depressive symptoms in logistic regression models adjusted for HIV status and smoking (p < 0.05). …”
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    Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms
  18. 20558
    por Rezk, N., Richards, J.B.
    Publicado 2022
    “…RÉSULTATS: La première étude a pu identifier que l'OAS-1 (2′-5′-Oligoadenylate Synthetase 1) est un gène protecteur qui permet de ne pas faire de forme grave de la maladie. …”
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    88 - Des déterminants génétiques peuvent influencer la sensibilité et la gravité de la COVID-19
  19. 20559
    “…Also, IBDV-induced expression of IFN-β, Mx and OAS genes was reduced in chTRIM25 knockout as compared to wild-type cells, hence contributing to the enhancement of IBDV replication. …”
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    Interaction between chicken TRIM25 and MDA5 and their role in mediated antiviral activity against IBDV infection
  20. 20560
    “…The interferon-induced protein with tetratricopeptide repeats (IFIT)1, IFIT2, IFIT3, interferon, α-inducible protein (IFI)6 (also known as G1P3), interferon regulatory factor 9 (IRF9, ISGF3), 2′–5′-oligoadenylate synthetase 1, 40/46 kDa (OAS1) and signal transducer and activator of transcription 1 (STAT1) genes all showed changes in expression following treatment with thymoquinone. …”
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    Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells
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