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  1. 2041
    “…Bone marrow lesions (BMLs) are common and important magnetic resonance imaging (MRI) features in OA patients. Basic and clinical research on subchondral BMLs in the pathogenesis of OA has been a hotspot. …”
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    Bone marrow lesions in osteoarthritis: From basic science to clinical implications
  2. 2042
    “…The aim of the present analysis was to characterise the economic burden of moderate-to-severe pain associated with CLBP + OA and CLBP alone compared with general population-matched controls without CLBP or OA. …”
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    Chronic Low Back Pain with and without Concomitant Osteoarthritis: A Retrospective, Longitudinal Cohort Study of Patients in England
  3. 2043
    “…Integrated analysis of worldwide OA factors is used to present a holistic regional and global description of OA. …”
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    Understanding atmospheric organic aerosols via factor analysis of aerosol mass spectrometry: a review
  4. 2044
    “…The purpose of the present study was to investigate the association and effects of adiponectin on inflammation and cartilage destruction in osteoarthritis (OA). METHODS: Cartilage and blood samples were collected from 35 male OA patients undergoing total knee replacement surgery. …”
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    Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways
  5. 2045
    “…Objective: To assess a mitochondrion-related phenotype in patients with osteoarthritis (OA). Methods: Serum levels of the following OA-related biomarkers: matrix metalloproteinase-1 (MMP-1); MMP-3; MMP-13; myeloperoxidase (MPO); a peptide of the alpha-helical region of type II collagen, Coll2-1, and its nitrated form Coll2-1NO(2); a C-terminal neoepitope generated by the collagenase-mediated cleavage of collagen type II triple helix, C2C; the C-propeptide of collagen type II, CPII; hyaluronic acid (HA); human cartilage glycoprotein 39, YKL-40; cartilage oligomeric matrix protein; and cathepsin K were analyzed in 48 OA patients and 52 healthy controls carrying the haplogroups H and J. …”
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    Mitochondrial Haplogroups Define Two Phenotypes of Osteoarthritis
  6. 2046
    “…PURPOSE: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). …”
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    Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee
  7. 2047
    por Björk, Bo-Christer, Solomon, David
    Publicado 2012
    “…Our aim was to inform this debate by comparing the scientific impact of OA journals with subscription journals, controlling for journal age, the country of the publisher, discipline and (for OA publishers) their business model. …”
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    Open access versus subscription journals: a comparison of scientific impact
  8. 2048
    “…BACKGROUND: Osteoarthritis (OA) is a common condition managed in general practice, but often not in line with published guidance. …”
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    Developing a model osteoarthritis consultation: a Delphi consensus exercise
  9. 2049
    “…The mean NRSS was also higher in severe OA TKR patients. DISCUSSION: Patients with severe OA have a better prognosis after THR and TKR than patients with mild OA. …”
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    Patients with Severe Radiographic Osteoarthritis Have a Better Prognosis in Physical Functioning after Hip and Knee Replacement: A Cohort-Study
  10. 2050
    “…Whole blood of 65 OA outpatients, 27 end-stage OA patients, 27 healthy volunteers, and knee articular cartilages of 28 end-stage OA patients and 26 healthy subjects were examined. …”
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    Differences in Mammalian Target of Rapamycin Gene Expression in the Peripheral Blood and Articular Cartilages of Osteoarthritic Patients and Disease Activity
  11. 2051
    “…In order to evaluate the reaction of human colon cells to USPIO NPs, the effects of non-stabilized USPIO NPs (NS-USPIO NPs), oleic-acid-stabilized USPIO NPs (OA-USPIO NPs), and free oleic acid (OA) were compared in human HT29 and CaCo(2) colon epithelial cancer cells. …”
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    Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles
  12. 2052
    “…OBJECTIVE: Osteoarthritis (OA) is a common debilitating disease that results in degeneration of cartilage and bone in the synovial joints. …”
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    Evidence from Raman Spectroscopy of a Putative Link Between Inherent Bone Matrix Chemistry and Degenerative Joint Disease
  13. 2053
    “…OBJECTIVE: To investigate the role of hypoxia in the pathology of osteoarthritic (OA) bone by exploring its effect on the phenotype of isolated primary osteoblasts from patients with knee OA. …”
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    Hypoxia Modulates the Phenotype of Osteoblasts Isolated From Knee Osteoarthritis Patients, Leading to Undermineralized Bone Nodule Formation
  14. 2054
    “…We previously reported an association between high bone mass (HBM) and a bone-forming phenotype of radiographic hip osteoarthritis (OA). As knee and hip OA have distinct risk factors, in this study we aimed to determine (i) whether HBM is also associated with knee OA, and (ii) whether the HBM knee OA phenotype demonstrates a similar pattern of radiographic features to that observed at the hip. …”
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    Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis
  15. 2055
    “…INTRODUCTION: High joint loading, knee muscle weakness, and poor proprioceptive acuity are important factors that have been linked to knee osteoarthritis (OA). We previously reported that those with unilateral hip OA and bilateral asymptomatic knees are more predisposed to develop progressive OA in the contralateral knee relative to the ipsilateral knee. …”
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    Asymmetries and relationships between dynamic loading, muscle strength, and proprioceptive acuity at the knees in symptomatic unilateral hip osteoarthritis
  16. 2056
    “…BACKGROUND: OA is a complex disease caused by environmental and genetic risk factors. …”
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    A genome-wide association study of copy-number variation identifies putative loci associated with osteoarthritis in Koreans
  17. 2057
    “…SIMPLE SUMMARY: Feline osteoarthritis (OA) is challenging to diagnose. A pain scale was developed for use by veterinarians, in association with their physical examination, and tested for reliability and validity. …”
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    Preliminary Validation and Reliability Testing of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians, in a Colony of Laboratory Cats
  18. 2058
    “…BACKGROUND: Females have a two-fold risk of developing knee osteoarthritis (OA) as compared to their male counterparts and atypical walking gait biomechanics are also considered a factor in the aetiology of knee OA. …”
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    Gender differences in gait kinematics for patients with knee osteoarthritis
  19. 2059
    “…BACKGROUND: Osteoarthritis (OA) is a complex arthritic condition in which the genetic factor plays a crucial role. …”
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    Association of rs1137101 polymorphism in LEPR and susceptibility to knee osteoarthritis in a Northwest Chinese Han population
  20. 2060
    “…OBJECTIVE: To assess the ability of matriptase, a type II transmembrane serine proteinase, to promote aggrecan loss from the cartilage of patients with osteoarthritis (OA) and to determine whether its inhibition can prevent aggrecan loss and cartilage damage in experimental OA. …”
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    Matriptase Induction of Metalloproteinase‐Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms
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