“…RESULTS: The microarchitectural properties of femoral head cancellous bone revealed significant differences among the 4 groups, but not between RA and OA. Bone volume fraction was significantly greater in the RA and the OA than in the OP and the CNT. …”
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“…Conditions that resemble osteoarthritis (OA) were produced by injection of sodium monoiodoacetate (MIA) into the knee joints of mice. …”
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“…The sclerotial biomass in the Low OA group increased by 66%, however, no sclerotia formed in the High OA group. …”
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“…To investigate the effects and mechanisms of irisin, a newly discovered myokine, in cartilage development, osteoarthritis (OA) pathophysiology and its therapeutic potential for treating OA we applied the following five strategical analyses using (1) murine joint tissues at different developmental stages; (2) human normal and OA pathological tissue samples; (3) experimental OA mouse model; (4) irisin gene knockout (KO) and knock in (KI) mouse lines and their cartilage cells; (5) in vitro mechanistic experiments. …”
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“…METHODS: Patients with early knee OA (n = 29) and end-stage knee OA (n = 22) were recruited. …”
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“…The present review summarizes all known SNPs of MMP genes related to a higher risk of knee OA. There are at least nine SNPs in four MMP genes associated with knee OA. …”
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“…Two clusters in the OA group (OA1 and OA2) were distinguished by the key microbiota Firmicutes and Enterobacteriaceae. …”
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“…The green-lipped mussel (GLM) contains novel omega-3 polyunsaturated fatty acids, which exhibit anti-inflammatory and joint-protecting properties. Osteoarthritis (OA) is a degenerative joint disease characterized by a progressive loss of cartilage; oxidative stress plays a role in the pathogenesis of OA. …”
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“…Osteoarthritis (OA) is known to involve profound changes in bone density and microstructure near to, and even distal to, the joint. …”
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“…We found that OA treatment markedly inhibited pyroptosis. qRT–PCR and western blot revealed that OA suppressed the expression of pyroptosis-associated genes. …”
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“…As life expectancy increases, Osteoarthritis (OA) is becoming a more frequently seen chronic joint disease. …”
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“…OBJECTIVE: Ankle osteoarthritis (OA) has a prevalence of 3.4% in the general population of which 70% to 78% is posttraumatic, affecting younger patients with a longer projected life span compared with hip and knee OA. …”
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“…Osmotic adjustment (OA) is a major component of drought resistance in crops. …”
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“…There was statistically significant (p < 0.0001) association between BMD and severity of OA knee. BMD decreased as the K-L grade of OA knee increased from 1 to 4. …”
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“…Osteoarthritis (OA) imposes an increasing social burden due to global activity limitations, especially among the aged. …”
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“…BACKGROUND: Degenerative rotator cuff tears and osteoarthritis (OA) are associated with differences in coronal plane scapular morphology, with particular focus on the effect of the critical shoulder angle (CSA) on shoulder biomechanics. …”
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“…Nanosecond transient absorption spectra, singlet oxygen quantum yields (Φ(Δ4OA-N) = 45.1%, Φ(Δ6OA-N) = 56.6%, and Φ(Δ8OA-N) = 65.7%) and theoretical calculations demonstrate that the torsion angle between the donor (naphthalene) and the acceptor (pyrimidine) promotes intersystem crossing (ISC), and the lifetime of the triplet state reaches ca. 8 ms. …”
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“…AIMS: To investigate the long-term risk of age-related macular degeneration (AMD) in persons with osteoarthritis (OA). METHODS: This retrospective cohort study first enrolled 71,609 subjects diagnosed with OA, and 236,169 without such a diagnosis between January 1, 2002 and December 31, 2005, from the Longitudinal Health Insurance Database 2005. …”
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“…Hip dysplasia is a common cause of hip pain and a known risk factor for hip osteoarthritis (OA) and early total hip arthroplasty (THA). Unfortunately, little is known about the specific factors associated with an increased risk of OA. …”
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“…We found that summer OA in Beijing features a higher degree of oxidation and a higher proportion of organosulfates (OSs) in comparison to OA during wintertime, which exhibits a high contribution from (nitro-)aromatic compounds. …”
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