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  1. 2281
    “…BACKGROUND: Early stage osteoarthritis (OA) is clinically asymptomatic due to the avascular and the aneural nature of the cartilage tissue. …”
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    Noninvasive visualization of early osteoarthritic cartilage using targeted nanosomes in a destabilization of the medial meniscus mouse model
  2. 2282
    “…However, its effects on osteoarthritis (OA) and its regulatory mechanisms have not been investigated by network analysis. …”
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    Protective Effects of Peucedanum japonicum Extract against Osteoarthritis in an Animal Model Using a Combined Systems Approach for Compound-Target Prediction
  3. 2283
    “…Osteoarthritis (OA) has become one of the most common disabilities among elders, especially in females. …”
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    Effect of Fucoidan on Anterior Cruciate Ligament Transection and Medial Meniscectomy Induced Osteoarthritis in High-Fat Diet-Induced Obese Rats
  4. 2284
    “…Omega-6 FAs are inflammatory mediators that are increased in joints with osteoarthritis (OA), but their association with OA progression is not yet well defined. …”
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    Omega-6 oxylipins generated by soluble epoxide hydrolase are associated with knee osteoarthritis
  5. 2285
    “…The adipokine adipsin is an emerging mediator of human osteoarthritis (OA) progression. Here, we investigated its in vivo role in the development of spontaneous OA in aging mice. …”
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    In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice
  6. 2286
    “…Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage degeneration and secondary osteogenesis. …”
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    CCAL1 enhances osteoarthritis through the NF‐κB/AMPK signaling pathway
  7. 2287
    “…Here, we investigated whether OA could attenuate DOX-induced acute cardiotoxicity in mice. …”
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    Protective Effects of Oroxylin A against Doxorubicin-Induced Cardiotoxicity via the Activation of Sirt1 in Mice
  8. 2288
    “…Background: Several pharmacological therapeutic approaches have been proposed to manage osteoarthritis (OA), including intra-articular (IA) injections. …”
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    The Rationale for the Intra-Articular Administration of Clodronate in Osteoarthritis
  9. 2289
    “…Existing treatment can only alleviate the symptoms and delay the progression of OA. Therefore, novel and effective therapeutics strategies for OA need to be developed. …”
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    Neutrophil Elastase Induces Chondrocyte Apoptosis and Facilitates the Occurrence of Osteoarthritis via Caspase Signaling Pathway
  10. 2290
    por Xu, Jin, Ma, Xinlong
    Publicado 2021
    “…Circular RNAs (circRNAs) are known to participate in the pathogenesis of multiple diseases, including OA. We investigated the functions of hsa_circ_0032131, a circRNA upregulated in OA, using CHON-001 cells and an in vivo OA rat model. …”
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    Hsa_circ_0032131 knockdown inhibits osteoarthritis progression via the miR-502-5p/PRDX3 axis
  11. 2291
    “…F) were treated monthly with oxalic acid (OA) at 0.1, 0.5, and 1 mM from initial fruit growth on the tree until harvest in2019. …”
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    Preharvest Treatment with Oxalic Acid Improves Postharvest Storage of Lemon Fruit by Stimulation of the Antioxidant System and Phenolic Content
  12. 2292
    “…The purpose of this communication is to provide an overview as well as the strengths and weaknesses of Overeaters Anonymous (OA) as an intervention for binge eating disorder treatment. …”
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    Overeaters Anonymous: An Overlooked Intervention for Binge Eating Disorder
  13. 2293
    “…There is a great need for quantitative outcomes reflecting the functional status in patients with knee or hip osteoarthritis (OA) to advance the development and investigation of interventions for OA. …”
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    Assessing Site Specificity of Osteoarthritic Gait Kinematics with Wearable Sensors and Their Association with Patient Reported Outcome Measures (PROMs): Knee versus Hip Osteoarthritis
  14. 2294
    “…INTRODUCTION: Oleanolic acid (OA) has been shown to be useful for the treatment of mental disorders. …”
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    Oleanolic Acid Attenuates Morphine Withdrawal Symptoms in Rodents: Association with Regulation of Dopamine Function
  15. 2295
    “…Airborne particulate matter (PM) is one of the indicators of air pollution, and it is also the main factor causing oxidative stress in the skin. Oleanolic acid (OA), a natural terpenoid compound, effectively inhibited PM-induced skin aging; however, OA has poor water solubility and skin absorption, which limit its application in medicines and cosmetics. …”
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    Oleanolic Acid Nanofibers Attenuated Particulate Matter-Induced Oxidative Stress in Keratinocytes
  16. 2296
    “…Osteoarthritis (OA), the most common degenerative and inflammatory joint disorder, is multifaceted. …”
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    Pro-regenerative Dialogue Between Macrophages and Mesenchymal Stem/Stromal Cells in Osteoarthritis
  17. 2297
    “…Background: Physical therapy (PT) is recommended as first-line management for osteoarthritis (OA). The purpose of this study was to assess the PT use among adults with OA and those without (Non-OA) and subsequently identify associated factors among these populations. …”
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    Physical Therapy Use and Associated Factors in Adults with and without Osteoarthritis—An Analysis of the Population-Based German Health Update Study
  18. 2298
    “…Knee osteoarthritis (OA) is the most common form of arthritis and it has been known as the main factor of lower limb disability. …”
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    Vitamin K and D Status in Patients with Knee Osteoarthritis: An Analytical Cross-sectional Study
  19. 2299
    “…PLGA_IO-OA_OXA and PEGylated PLGA_IO-OA_OXA nanoparticles displayed a comparable mean diameter of 207 ± 70 nm and 185 ± 119 nm, respectively. …”
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    Antibody Conjugated PLGA Nanocarriers and Superparmagnetic Nanoparticles for Targeted Delivery of Oxaliplatin to Cells from Colorectal Carcinoma
  20. 2300
    “…Based on the pseudo-ternary phase diagram and loading capacity test, the optimal ratio of OA-SMEDDS with CLT was selected. CLT-loaded OA-SMEDDS not only bears a higher drug loading capacity but also maintains good storage stability. …”
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    Oleic Acid-Based Self Micro-Emulsifying Delivery System for Enhancing Antifungal Activities of Clotrimazole
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