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  1. 2421
    “…Osteoarthritis (OA) is a severe, common chronic orthopaedic disorder characterised by a degradation of the articular cartilage with an incidence that increases over years. …”
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    Mitochondrial Genome Editing to Treat Human Osteoarthritis—A Narrative Review
  2. 2422
    “…Osteoarthritis (OA) is a severe musculoskeletal disease with an increasing incidence in the worldwide population. …”
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    Benefits of Applying Nanotechnologies to Hydrogels in Efficacy Tests in Osteoarthritis Models—A Systematic Review of Preclinical Studies
  3. 2423
    por Kim, Yu Seon, Guilak, Farshid
    Publicado 2022
    “…Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of the joints, degradation of cartilage, and the remodeling of other joint tissues. …”
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    Engineering Hyaluronic Acid for the Development of New Treatment Strategies for Osteoarthritis
  4. 2424
    “…Osteoarthritis (OA) is a common degenerative disease of the joints. …”
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    A new strategy for osteoarthritis therapy: Inhibition of glycolysis
  5. 2425
    por McDougall, Jason J.
    Publicado 2019
    “…OBJECTIVE: This commentary aims to summarise the importance of the joint nervous system in maintaining joint homeostasis and the role of nerves in contributing to degenerative diseases such as osteoarthritis (OA). METHODS: Pertinent scientific literature was evaluated and summarised to form the hypothesis that OA is a neurological disease. …”
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    Osteoarthritis is a neurological disease – an hypothesis
  6. 2426
    “…Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis. …”
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    Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis
  7. 2427
    “…Osteoarthritis (OA) is the most common joint disease primarily characterized by cartilage degeneration. …”
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    Oral Administration of Bovine Milk-Derived Extracellular Vesicles Attenuates Cartilage Degeneration via Modulating Gut Microbiota in DMM-Induced Mice
  8. 2428
    “…Osteoarthritis (OA) is a highly prevalent degenerative joint condition that disproportionately affects females. …”
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    Proteomic Analysis of Female Synovial Fluid to Identify Novel Biomarkers for Osteoarthritis
  9. 2429
    “…The association between dietary macronutrient distribution and the risk of OA remains unknown. We aimed to evaluate how dietary macronutrient distribution was correlated with the risk of OA in US adults. …”
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    Association of macronutrients intake distribution with osteoarthritis risk among adults in NHANES, 2013–2016
  10. 2430
    por Li, Zhuang, Lu, Jun
    Publicado 2023
    “…Osteoarthritis (OA) is the most common joint disease globally, and its progression is irreversible. …”
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    CircRNAs in osteoarthritis: research status and prospect
  11. 2431
    “…We describe here the development and validation of the Osteoarthritis Symptom Inventory Scale (OASIS), a new self-administered questionnaire specifically designed to evaluate the various osteoarthritis (OA) pain symptoms with different dimensions related to OA pain mechanisms. …”
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    Three dimensions of pain in osteoarthritis: development and validation of the Osteoarthritis Symptom Inventory Scale
  12. 2432
    por Khader, Ateka, Alquran, Hiam
    Publicado 2023
    “…Osteoarthritis (OA) is the most common arthritis and the leading cause of lower extremity disability in older adults. …”
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    Automated Prediction of Osteoarthritis Level in Human Osteochondral Tissue Using Histopathological Images
  13. 2433
    “…Accurate evaluation of morphological changes in articular cartilage are necessary for early detection of osteoarthritis (OA). 3T magnetic resonance imaging (MRI) has highly sensitive contrast resolution and is widely used clinically to detect OA. …”
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    MRI overestimates articular cartilage thickness and volume compared to synchrotron radiation phase-contrast imaging
  14. 2434
    “…We have compared the distribution of the receptor tyrosine kinase (Tie) and the Ang ligands in synovial tissues from normal subjects and those with rheumatoid arthritis (RA) and osteoarthritis (OA). Immunohistochemical analysis was used to determine the expression of Ang-1, Ang-2, Tie1 and Tie2 in synovial tissue of normal subjects and those with RA and OA. …”
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    Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue
  15. 2435
    “…METHODS: OA patients and controls from three European populations (Greece, Spain and the UK) adding up to 1003 patients (716 women, 287 men) that had undergone total knee joint replacement (TKR) due to severe primary OA and 1543 controls (758 women, 785 men) lacking clinical signs or symptoms of OA were genotyped for the D6S1276 microsatellite in intron 1 of BMP5. …”
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    Association of a BMP5 microsatellite with knee osteoarthritis: case-control study
  16. 2436
    “…Despites the fact that T cells are involved in the pathogenesis of osteoarthritis (OA) little is known about the roles of CD8(+) T cells in this disease. …”
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    CD8(+) T Cell-Induced Expression of Tissue Inhibitor of Metalloproteinses-1 Exacerbated Osteoarthritis
  17. 2437
    “…Oseltamivir (OA), an ethyl ester prodrug of oseltamivir carboxylate (OC), is clinically used as a potent and selective inhibitor of neuraminidase. …”
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    Bench to Bed Evidences for Pharmacokinetic and Pharmacodynamic Interactions Involving Oseltamivir and Chinese Medicine
  18. 2438
    “…Osteoarthritis (OA) is the most prevalent form of arthritis and its multifactorial nature has been increasingly recognized. …”
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    Association of Single Nucleotide Polymorphisms in Estrogen Receptor Alpha Gene with Susceptibility to Knee Osteoarthritis: A Case-Control Study in a Chinese Han Population
  19. 2439
    “…Flunixin meglumine temporarily permitted OA-prone animals to move in a manner that was analogous to OA-resistant animals.…”
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    Quantitative Gait Analysis Detects Significant Differences in Movement between Osteoarthritic and Nonosteoarthritic Guinea Pig Strains before and after Treatment with Flunixin Meglumine
  20. 2440
    “…Ihh expression was increased 5.2-fold in OA cartilage, 3.1-fold in relative normal OA cartilage, and 1.71-fold in OA SF compared to normal control samples. …”
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    Indian Hedgehog in Synovial Fluid Is a Novel Marker for Early Cartilage Lesions in Human Knee Joint
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