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  1. 2681
    “…BACKGROUND: In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. …”
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    Allelic variants of IL1R1 gene associate with severe hand osteoarthritis
  2. 2682
    “…Exercise therapy is generally recommended in osteoarthritis (OA) of the hip or knee. However, coexisting disorders may bring additional impairments, which may necessitate adaptations to exercise for OA of the hip or knee. …”
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    Osteoarthritis of the hip or knee: which coexisting disorders are disabling?
  3. 2683
    “…RESULTS: The study included 117 patients who underwent LA and 80 who underwent OA. Of 122 acute appendicitis cases, mean operating times were 47 minutes (LA) and 48 minutes (OA). …”
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    Laparoscopic Appendectomy in Children After the Learning Curve
  4. 2684
    “…Oleanolic acid (OA) and ursolic acid (UA) have been proven to possess many biological activities, and much attention is focused on the search for plants which are rich in OA and UA. …”
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    Herbaceous Peony (Paeonia lactiflora Pall.) as an Alternative Source of Oleanolic and Ursolic Acids
  5. 2685
    “…BACKGROUND: Previous research on time to referral to orthopaedic surgery has predominantly used hip complaints as starting point instead of the moment the diagnosis of osteoarthritis (OA) of the hip is established, therefore little is known about the length of time a patient diagnosed with hip OA stays under the care of a general practitioner (GP). …”
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    Online Artículo Texto
    Time spent in primary care for hip osteoarthritis patients once the diagnosis is set: a prospective observational study
  6. 2686
    “…Suppression of this matrix-degrading enzyme by simvastatin also reduced OARSI scores, suggesting the potential for statins against OA progression. CONCLUSIONS: Following knee trauma, OA initiates at the molecular level in a short period of time. …”
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    Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3
  7. 2687
    “…Using the K&L grading, inter-observer agreement was moderate (kappa = 0.55), but kappa increased when the number of categories was reduced from 5 to 3 (no OA, mild OA, and severe OA). The Croft classification gave similar agreement as the K&L grading. …”
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    Radiographic evaluation of osteoarthritis of the hip: An inter-observer study of 61 hips treated for late-detected developmental hip dislocation
  8. 2688
    “…BACKGROUND: The natural history of occupational asthma (OA) is influenced by many determinants. This study aims to assess the combined roles of personal characteristics, including occupational exposure and nutritional habits, on the incidence of OA during the first years at work. …”
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    Diet, occupational exposure and early asthma incidence among bakers, pastry makers and hairdressers
  9. 2689
    “…HtrA1, Ddr-2, and Mmp-13 are reliable biomarkers for osteoarthritis (OA), yet the exact mechanism for the upregulation of HtrA-1 is unknown. …”
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    Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE)
  10. 2690
    “…BACKGROUND: The investigation and comparison of the effects of acupuncture and isometric exercises on pain and quality of life in patients suffering from knee osteoarthritis (OA). OA is the most common form of joint disease and one leading cause of disability in the elderly. …”
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    Comparison of the Effects of Acupuncture and Isometric Exercises on Symptom of Knee Osteoarthritis
  11. 2691
    “…BACKGROUND: Osteoarthritis (OA) is a destructive joint disease and there are no known biomarkers available for an early diagnosis. …”
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    Quantitative proteomics reveals regulatory differences in the chondrocyte secretome from human medial and lateral femoral condyles in osteoarthritic patients
  12. 2692
    “…The more joint regions involved, the more likely that the OA was disabling. OA prevalence was higher in females and increased with age. …”
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    Defining and mapping the person with osteoarthritis for population studies and public health
  13. 2693
    “…In this study, cartilage of rabbit OA model and human OA samples was examined by macroscopic evaluation, ultrasound signal intensity, histology with Mankin scores, and Fourier transform infrared imaging (FTIRI) analysis. …”
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    Ultrasound Can Detect Macroscopically Undetectable Changes in Osteoarthritis Reflecting the Superficial Histological and Biochemical Degeneration: Ex Vivo Study of Rabbit and Human Cartilage
  14. 2694
    “…METHODS: Articular knee cartilage was obtained from nine osteoarthritis (OA) patients. mRNA levels for 27 glycosyltransferases were analyzed in OA chondrocytes using RT-qPCR. …”
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    Glycophenotyping of osteoarthritic cartilage and chondrocytes by RT-qPCR, mass spectrometry, histochemistry with plant/human lectins and lectin localization with a glycoprotein
  15. 2695
    “…Oleanolic acid (OA) has been used to treat liver disorders, but whether it can attenuate hepatic ischemia-reperfusion- (IR-) associated liver dysfunction remains unexplored. …”
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    Protective Effects of Pretreatment with Oleanolic Acid in Rats in the Acute Phase of Hepatic Ischemia-Reperfusion Injury: Role of the PI3K/Akt Pathway
  16. 2696
    “…Nitro-oleic acid (OA-NO2), acting as anti-inflammatory signaling mediators, are involved in multiple signaling pathways. …”
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    Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways
  17. 2697
    “…The following comparisons between LA and OA were done: mean operative time, mean hospital stay after surgery, conversion rate, proportion of LA to OA in successive years. …”
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    Utility of the laparoscopic approach to surgical treatment of acute appendicitis in a single surgical unit
  18. 2698
    “…We evaluated this possibility by measuring perceived hand size in healthy controls and those with painful hand OA before and after illusory hand resizing. The aim was to investigate whether people with painful hand OA have distorted representations of hand size and whether these representations are malleable. …”
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    Evidence for distorted mental representation of the hand in osteoarthritis
  19. 2699
    “…Lumbar facet joint (LFJ) osteoarthritis (OA) is an important etiology of low back pain. Several animal models of LFJ OA have been established using intraarticular injection of various chemicals. …”
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    Establishment of a rat model of lumbar facet joint osteoarthritis using intraarticular injection of urinary plasminogen activator
  20. 2700
    “…The primary aim of this study was to link CRF to neural white matter microstructure using diffusion tensor imaging in OA. METHODS: Young adults (YA; n = 32) and OA (n = 27) completed a graded maximal exercise test to evaluate CRF and diffusion tensor magnetic resonance imaging to examine neural white matter integrity. …”
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    Cardiorespiratory fitness is associated with white matter integrity in aging
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