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  1. 2741
    “…Previous studies identified that chondrocyte apoptosis serves an important role in osteoarthritis (OA). However, the mechanisms of cartilage degeneration induced by apoptosis remain unclear. …”
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    Effect of chondrocyte mitochondrial dysfunction on cartilage degeneration: A possible pathway for osteoarthritis pathology at the subcellular level
  2. 2742
    “…The in vivo effect of KGN thermogel on OA was examined in a rabbit OA model. The KGN thermogel showed a sustained in vitro release of KGN for 3 weeks. …”
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    Intra-articular Injection of Kartogenin-Incorporated Thermogel Enhancing Osteoarthritis Treatment
  3. 2743
    “…BACKGROUND: Osteoarthritis (OA) is a common cause of musculoskeletal disability among elders and is characterized by late-onset degeneration of articular cartilage. …”
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    Identifying the role of ASPN and COMP genes in knee osteoarthritis development
  4. 2744
    “…Age is a primary risk factor for osteoarthritis (OA). The mechanisms that contribute to OA are poorly understood and disease modifying treatments have not been identified. …”
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    DEVELOPING THE COMMON MARMOSET AS A TRANSLATIONAL MODEL OF AGE-RELATED OSTEOARTHRITIS
  5. 2745
    “…The aim of this study was to quantify and visualize the degenerative patterns of the talus in ankle osteoarthritis (OA). The differences in talar morphology between sides of patients with unilateral varus ankle OA (medial talar tilt > 4°) were compared. …”
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    Visualization and quantification of the degenerative pattern of the talus in unilateral varus ankle osteoarthritis
  6. 2746
    “…Osteoarthritis (OA) is a multifactorial and inflammatory disease characterized by cartilage destruction that can cause disability among aging patients. …”
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    KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo
  7. 2747
    “…Objective: Trefoil factor family peptide 3 (TFF3) has been shown to support catabolic functions in cases of osteoarthritis (OA). As in joint physiology and diseases such as OA, the synovial membrane (SM) of the joint capsule also plays a central role. …”
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    Human Synovia Contains Trefoil Factor Family (TFF) Peptides 1–3 Although Synovial Membrane Only Produces TFF3: Implications in Osteoarthritis and Rheumatoid Arthritis
  8. 2748
    “…BACKGROUND: Magnetic resonance imaging (MRI) of osteoarthritis (OA) of the knee is a preoperative method of joint assessment. …”
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    Histological Grade and Magnetic Resonance Imaging Quantitative T1rho/T2 Mapping in Osteoarthritis of the Knee: A Study in 20 Patients
  9. 2749
    “…Protosappanin‐A (PrA) and oleanolic acid (OA), which are important effective ingredients isolated from Caesalpinia sappan L., exhibit therapeutic potential in multiple diseases. …”
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    Protosappanin‐A and oleanolic acid protect injured podocytes from apoptosis through inhibition of AKT‐mTOR signaling
  10. 2750
    “…Mankin’s method was used to score the severity of OA. The animals were assigned into the OA group, OA+HW group, and sham operation group. …”
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    Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis
  11. 2751
    “…Osteoarthritis (OA) is a chronic joint function disorder with characteristics of chondrocytes reduction and extracellular matrix (ECM) components destruction. …”
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    miR-142-5p as a CXCR4-Targeted MicroRNA Attenuates SDF-1-Induced Chondrocyte Apoptosis and Cartilage Degradation via Inactivating MAPK Signaling Pathway
  12. 2752
    “…We also see a rise in transcriptomic studies examining organismal response to OA in a multi-stressor context, often reporting synergistic effects of OA and temperature. …”
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    Ocean acidification promotes broad transcriptomic responses in marine metazoans: a literature survey
  13. 2753
    “…PURPOSE: Osteoarthritis (OA) of the temporomandibular joint (TMJ) elicits cartilage and subchondral bone defects. …”
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    Local Injection of Growth Hormone for Temporomandibular Joint Osteoarthritis
  14. 2754
    “…The marine toxin okadaic acid (OA) provokes diarrhetic shellfish poisoning (DSP) syndrome characterized by severe gastrointestinal symptoms. …”
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    Degradation of okadaic acid in seawater by UV/TiO(2) photocatalysis – Proof of concept
  15. 2755
    “…OBJECTIVE: Recent research in knee osteoarthritis (OA) highlights the role of the meniscus in OA pathology. …”
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    Proteomic comparison of osteoarthritic and reference human menisci using data-independent acquisition mass spectrometry
  16. 2756
    “…Rationale: Osteoarthritis (OA) is the most common joint disease worldwide. …”
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    CircCDK14 protects against Osteoarthritis by sponging miR-125a-5p and promoting the expression of Smad2
  17. 2757
    “…The knowledge of the nociceptive mechanisms in OA, which will allow to develop effective therapies for OA pain, is of utmost need. …”
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    Nociceptive mechanisms driving pain in a post-traumatic osteoarthritis mouse model
  18. 2758
    “…Osteoarthritis (OA) is the most common degenerative joint disease, predicted to increase in incidence year by year due to an ageing population. …”
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    Mass Spectrometry Imaging as a Potential Tool to Investigate Human Osteoarthritis at the Tissue Level
  19. 2759
    “…RESULTS: Sixteen TMJs (6.1%) had no OA, 74 (28.6%) were indeterminate for OA, and 171 (65.5%) had OA. …”
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    Incidental findings of temporomandibular joint osteoarthritis and its variability based on age and sex
  20. 2760
    “…Radiographic osteoarthritis (OA) is most prevalent in the hand. The association of hand injury with pain or OA is unclear. …”
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    Cricket related hand injury is associated with increased odds of hand pain and osteoarthritis
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