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  1. 2761
    “…First, more female patients with OA experienced stress and depression than males. …”
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    Mental health and quality of life of patients with osteoarthritis pain: The sixth Korea National Health and Nutrition Examination Survey (2013–2015)
  2. 2762
    “…Older adults (OA) prefer positive over negative information in a lab setting, compared to young adults (i.e., positivity effects; YA). …”
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    Age Differences in Preferences for Fear-Enhancing Versus Fear-Reducing News in a Global Pandemic
  3. 2763
    “…We have reported the importance of ERRγ in osteoarthritis (OA) pathogenesis. However, therapeutic approaches with ERRγ against OA associated with inflammatory mechanisms remain limited. …”
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    GSK5182, 4-Hydroxytamoxifen Analog, a New Potential Therapeutic Drug for Osteoarthritis
  4. 2764
    “…BACKGROUND: Several studies have reported a high prevalence of osteoarthritis (OA) of the knee among agricultural workers. We investigated work-related factors that increase the risk of knee OA among Korean farmers. …”
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    Work-related factors of knee osteoarthritis in Korean farmers: a cross-sectional study
  5. 2765
    “…MSCs were abundant in OA talus and tibia, with similar colony characteristics. …”
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    Multipotential stromal cells in the talus and distal tibia in ankle osteoarthritis – Presence, potency and relationships to subchondral bone changes
  6. 2766
    “…Osteoarthritis (OA) manifests with chronic pain, motor impairment, and proprioceptive changes. …”
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    Reorganization of functional brain network architecture in chronic osteoarthritis pain
  7. 2767
    “…Old age and female sex are risk factors for the development of osteoarthritis (OA) and chronic pain. We investigated the effects of sex and age on pain modulatory networks in a healthy state and during OA progression. …”
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    Pain modulatory network is influenced by sex and age in a healthy state and during osteoarthritis progression in rats
  8. 2768
    “…OBJECTIVES: To collate the genes experimentally modulated in animal models of osteoarthritis (OA) and compare these data with OA transcriptomics data to identify potential therapeutic targets. …”
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    OATargets: a knowledge base of genes associated with osteoarthritis joint damage in animals
  9. 2769
    “…DESIGN: Genome-wide association study (GWAS) of OA was performed in UK Biobank (60,800 cases and 328,251 controls) to obtain genetic association estimates for OA risk. …”
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    Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization study
  10. 2770
    por Dou, Pengcheng, He, Yu, Yu, Bo, Duan, Juan
    Publicado 2020
    “…The correlation between DNA methyltransferases (DNMTs) and microRNAs (miRNAs) has been well-established, but its interaction in osteoarthritis (OA) has been barely clarified. This study aimed to analyze the relationship between DNMT3B and miR-29b as well as their implications in OA. …”
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    Downregulation of microRNA-29b by DNMT3B decelerates chondrocyte apoptosis and the progression of osteoarthritis via PTHLH/CDK4/RUNX2 axis
  11. 2771
    “…RESULTS: Offset analgesia was successfully elicited in OA(1°C) in experiment 1, and in OA(1°C) and OA(2°C) in experiment 2. …”
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    Offset analgesia and onset hyperalgesia with different stimulus ranges
  12. 2772
    “…BACKGROUND: Circular RNA (circRNA) has been shown to affect the pathological process of osteoarthritis (OA) and is expected to become a potential marker for disease diagnosis. …”
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    The role of circRNA derived from RUNX2 in the serum of osteoarthritis and its clinical value
  13. 2773
    “…Osteoarthritis (OA) is a progressive and disabling musculoskeletal disease affecting millions of people and resulting in major healthcare costs worldwide. …”
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    Models of Osteoarthritis: Relevance and New Insights
  14. 2774
    “…BACKGROUND: Osteoarthritis (OA) is one of the most common age-related degenerative diseases. …”
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    COL3A1 and MMP9 Serve as Potential Diagnostic Biomarkers of Osteoarthritis and Are Associated With Immune Cell Infiltration
  15. 2775
    por Liu, Yongbao, Zhang, Yanxiu
    Publicado 2021
    “…The circular RNA (circRNA) hsa_circ_0134111 is upregulated in the cartilage of OA patients; however, its potential role in OA pathogenesis and progression remains unexplored. …”
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    Hsa_circ_0134111 promotes osteoarthritis progression by regulating miR-224-5p/CCL1 interaction
  16. 2776
    “…Since the deep cause for the anti-oxidation of carnosic acid (CA) against oleic acid (OA) remains unclear, we focused on exploring the CA inhibition mechanism via a combined experimental and computational study. …”
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    A Deep Insight in the Antioxidant Property of Carnosic Acid: From Computational Study to Experimental Analysis
  17. 2777
    “…Recent studies have suggested an important role of circular RNAs (circRNAs/circs) in OA. The present study aimed to investigate whether circRNAs might have a role in mechanical instability-regulated chondrocyte matrix metabolism in OA. …”
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    circPhc3 sponging microRNA-93-3p is involved in the regulation of chondrocyte function by mechanical instability in osteoarthritis
  18. 2778
    por Xie, Yutong, Wu, Jiayi, Yow, W Quin
    Publicado 2021
    “…Majority of older adults (OA) do not use technology frequently. For example, 84% of Singapore OA own a smartphone, however, only 22% have tried apps like online shopping. …”
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    How Can We Encourage Older Adults to Adopt Digital Services?
  19. 2779
    “…Objective: Long non-coding RNAs (lncRNAs) and their target microRNAs were documented in multiple studies to have a significant role in different joint disorders such as rheumatoid arthritis (RA) and osteoarthritis (OA). The current work aimed to determine the potential role of lnc-PVT1 and miR-146a as promising biomarkers to distinguish between RA, OA patients, and healthy individuals. …”
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    Long Non-Coding RNA PVT1 and Its Target miRNA-146a as Potential Prognostic Biomarkers in Rheumatoid Arthritis Patients
  20. 2780
    “…Whether PAR4 is involved in osteoarthritis (OA) pain has not yet been explored. The aim of this study was to compare the role of PAR4 in modulating early versus late stage OA pain using two models of OA viz. monoiodoacetate (MIA) and medial meniscal transection (MMT). …”
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    Targeting Proteinase Activated Receptor-4 Reduces Mechanonociception During the Acute Inflammatory Phase but not the Chronic Neuropathic Phase of Osteoarthritis in Rats
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