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  1. 2861
    “…Several studies dealing with the pathomechanisms of OA refer to MMP-1, -3, -7, -8, and -13 whereas a smaller number of investigations have pointed out the pathogenic role of gelatinases in OA. …”
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    Recent Findings on the Role of Gelatinases (Matrix Metalloproteinase-2 and -9) in Osteoarthritis
  2. 2862
    “…Osteoarthritis (OA) is the most frequent cause of disability in the USA, affecting up to 32.8% of patients over the age of sixty. …”
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    Online Artículo Texto
    Shoulder Osteoarthritis
  3. 2863
    “…The most significant impact of obesity on the musculoskeletal system is associated with osteoarthritis (OA), a disabling degenerative joint disorder characterized by pain, decreased mobility and negative impact on quality of life. …”
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    Obesity & osteoarthritis
  4. 2864
    “…Osteoarthritis (OA) is one of the most devastating chronic conditions that affect people around the world. …”
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    Online Artículo Texto
    Osteoarthritis in Young, Active, and Athletic Individuals
  5. 2865
    “…Therefore, we aimed to assess the correlation of adrenomedullin concentrations with the presence and grade of severity of knee osteoarthritis (OA). MATERIAL/METHODS: We recruited 187 knee OA patients and 109 healthy subjects. …”
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    Correlation of Adrenomedullin Concentrations with Knee Osteoarthritis Grade
  6. 2866
    “…BACKGROUND: Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is up-regulated in osteoarthritis (OA). Therefore, we aim to evaluate the correlation between gremlin-1 concentrations and the onset and severity of OA. …”
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    Online Artículo Texto
    Gremlin-1 Concentrations Are Correlated with the Severity of Knee Osteoarthritis
  7. 2867
    “…Osteoarthritis (OA), a common joint disease in elderly, causes serious social and economic burdens worldwide. …”
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    Online Artículo Texto
    The potential roles of circRNAs in osteoarthritis: a coming journey to find a treasure
  8. 2868
    por Rockel, Jason S., Kapoor, Mohit
    Publicado 2018
    “…Osteoarthritis (OA) is a progressive, deteriorative disease of articular joints. …”
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    Online Artículo Texto
    The Metabolome and Osteoarthritis: Possible Contributions to Symptoms and Pathology
  9. 2869
    “…Osteoarthritis (OA), the most common form of arthritis, may be triggered by improper secretion of circadian clock-regulated hormones, such as melatonin, thyroid-stimulating hormone (TSH), or cortisol. …”
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    Physiological and Pathological Role of Circadian Hormones in Osteoarthritis: Dose-Dependent or Time-Dependent?
  10. 2870
    por Duan, Ran, Xie, Hui, Liu, Zheng-Zhao
    Publicado 2020
    “…The pathological changes of osteoarthritis (OA) mostly revolve around the apoptosis and dysfunction of chondrocytes. …”
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    The Role of Autophagy in Osteoarthritis
  11. 2871
    por Rim, Yeri Alice, Ju, Ji Hyeon
    Publicado 2020
    “…Osteoarthritis (OA) is a chronic degenerative joint disease where the main characteristics include cartilage degeneration and synovial membrane inflammation. …”
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    The Role of Fibrosis in Osteoarthritis Progression
  12. 2872
    por Hu, Qichan, Ecker, Melanie
    Publicado 2021
    “…Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of articular cartilage and chronic inflammation of surrounding tissues. …”
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    Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis
  13. 2873
    “…Osteoarthritis (OA) is a disease which results in degeneration of cartilage within joints and affects approximately 13.6% of adults over 20 years of age in Canada and the United States of America. …”
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    Omega-3 Fatty Acids for the Management of Osteoarthritis: A Narrative Review
  14. 2874
    “…Osteoarthritis (OA) is the most common degenerative disease of the connective tissue of the human musculoskeletal system. …”
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    Soluble and EV-Associated Diagnostic and Prognostic Biomarkers in Knee Osteoarthritis Pathology and Detection
  15. 2875
    “…Osteoarthritis (OA) is a frequently seen degenerative joint disease in the elderly. …”
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    Tizoxanide as a novel theraputic candidate for osteoarthritis
  16. 2876
    por Liu, Lin, Tang, Haifeng, Wang, Yanjun
    Publicado 2023
    “…Nevertheless, an urgent necessity exists for a comprehensive synthesis of the most recent advances in polymeric DDS, providing valuable guidance for their implementation in the context of OA therapy. This review is dedicated to summarizing and examining recent developments in the utilization of polymeric DDS for OA therapy. …”
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    Polymeric biomaterials: Advanced drug delivery systems in osteoarthritis treatment
  17. 2877
    “…To identify whether a shared genetic influence accounts for the occurrence of OA at different skeletal sites. Methods. Multivariate modelling of data on prevalent radiographic OA at the hand (DIP, PIP and CMC joints), hip and knee joints assessed in 992 monozygotic and dizygotic female twin participants from the TwinsUK Registry. …”
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    The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee
  18. 2878
    por Bullock, C. M., Kelly, S.
    Publicado 2013
    “…Osteoarthritis (OA) pain is poorly understood and managed, as current analgesics have only limited efficacy and unwanted side effect profiles. …”
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    Calcitonin Gene-Related Peptide Receptor Antagonists: Beyond Migraine Pain—A Possible Analgesic Strategy for Osteoarthritis?
  19. 2879
    “…Osteoarthritis (OA) is the most common arthritis which affects the human body and can affect the temporomandibular joint (TMJ). …”
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    CT Images of a Severe TMJ Osteoarthritis and Differential Diagnosis with Other Joint Disorders
  20. 2880
    “…The aim of this study was to analyze the effect of Okadaic Acid (OA) on the proliferation of gastric and colon epithelial cells, the main target tissues of the toxin. …”
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    Okadaic Acid Toxin at Sublethal Dose Produced Cell Proliferation in Gastric and Colon Epithelial Cell Lines
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