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  1. 3061
    “…BACKGROUND: Much observational research reported that tea consumption decreases the risk of osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP) which are the three major bone disorders. …”
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    Causal Association Between Tea Consumption and Bone Health: A Mendelian Randomization Study
  2. 3062
    “…Cartilage micro‐cracks were increased during moderate and severe OA, while bone cracks were increased during mild and severe OA. …”
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    Sex, but not age and bone mass index positively impact on the development of osteochondral micro‐defects and the accompanying cellular alterations during osteoarthritis progression
  3. 3063
    “…Objectives: This study aimed to identify novel biomarkers for osteoarthritis (OA) and explore potential pathological immune cell infiltration. …”
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    Evaluation of Biomarkers and Immune Microenvironment of Osteoarthritis: Evidence From Omics Data and Machine Learning
  4. 3064
    “…OBJECTIVE: Pain sensitization is associated with pain severity in persons with hand OA. What contributes to pain sensitization is unclear. …”
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    Associations between joint pathologies and central sensitization in persons with hand osteoarthritis: results from the Nor-Hand study
  5. 3065
    “…Therefore, LINC00707 and miR-199-3p may interact with each other to participate in OA. In this study, the expression of LINC00707 and miR-199-3p in both OA and normal articular cartilage tissues was analyzed using RT-qPCR. …”
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    Long intergenic non-protein coding RNA 00707 regulates chondrocyte apoptosis and proliferation in osteoarthritis by serving as a sponge for microRNA-199-3p
  6. 3066
    “…For this purpose, the IFP-SM AFUs of both healthy donors (non-OA IFP-SM AFUs, n = 10) and OA patients (OA IFP-SM AFUs, n = 10) were processed by histology and immunohistochemistry. …”
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    Infrapatellar Fat Pad-Synovial Membrane Anatomo-Fuctional Unit: Microscopic Basis for Piezo1/2 Mechanosensors Involvement in Osteoarthritis Pain
  7. 3067
    “…OBJECTIVES: Data on work participation impairment and related societal costs for patients with hand osteoarthritis (OA) are scarce. Therefore, we aimed to investigate the association of hand OA with work limitations and costs of productivity loss in paid and unpaid work. …”
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    Hand osteoarthritis is associated with limitations in paid and unpaid work participation and related societal costs: the HOSTAS cohort
  8. 3068
    “…The aim of this study was the determination of serum hormonal levels and testicular long axis cut off points to distinguish obstructive azoospermia (OA) from non-OA (NOA) in Iranian patients as well as the evaluation of the necessity of diagnostic testis biopsy in azoospermic patients. …”
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    Evaluation of Azoospermic Patients to Distinguish Obstructive from Non-Obstructive Azoospermia, and Necessity of Diagnostic Testis Biopsy: A Retrospective Study
  9. 3069
    “…Moreover, the expression level of HK2 in OA synovial tissue (FLS) was higher than that in control group, which indicated the potential therapeutic effect of HK2 in OA. …”
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    HK2: a potential regulator of osteoarthritis via glycolytic and non-glycolytic pathways
  10. 3070
    por Lu, Danqing, Ding, Xiaomin, Lu, Wenqing
    Publicado 2022
    “…OBJECTIVE: The purpose of this study was to investigate the influencing factors of osteoarthritis (OA) in a southern Chinese population and to provide a scientific basis for the prevention and treatment of OA. …”
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    Study on the Influencing Factors of Osteoarthritis in Southern China
  11. 3071
    “…BACKGROUND AND AIM: Osteoarthritis (OA) is a chronic, painful, degenerative inflammatory disease of the synovial joints. …”
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    Long-term intake of Lilium lancifolium mitigated osteoarthritic effects by suppressing inflammatory cytokines in a dog model
  12. 3072
    “…Osteoarthritis (OA) is a common chronic musculoskeletal disease reported in veterinary clinics that severely reduces the quality of life of animals. …”
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    Natural product, bilobalide, improves joint health in rabbits with osteoarthritis by anti-matrix degradation and antioxidant activities
  13. 3073
    “…Osteoarthritis (OA) is a common disorder and a major cause of disability in the elderly population. …”
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    Induced inactivation of Wnt16 in young adult mice has no impact on osteoarthritis development
  14. 3074
    “…BACKGROUND: Osteoarthritis (OA) is a common clinical disease caused by a variety of factors, including genetic variants. …”
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    A transcriptome-wide association study provides new insights into the etiology of osteoarthritis
  15. 3075
    “…IVW analysis indicated that each additional year in AFB was associated with a decreasing risk of hip and/or knee OA and overall OA (hip and/or knee OA: OR = 0.79, 95% CI: 0.64–0.93, P = 1.33 × 10(−3); overall OA: OR = 0.80, 95% CI: 0.68–0.92, P = 1.80 × 10(−4)). …”
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    Using genetic instruments to estimate the causal effect of hormonal reproductive factors on osteoarthritis
  16. 3076
    “…AIMS: Osteoarthritis (OA) is a common degenerative joint disease worldwide, which is characterized by articular cartilage lesions. …”
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    Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis
  17. 3077
    “…Emerging observational data suggest that vitamin D deficiency is associated with the onset and progression of knee osteoarthritis (OA). However, the relationship between vitamin D level and OA and the role of vitamin D supplementation in the prevention of knee OA are controversial. …”
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    1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice
  18. 3078
    “…BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease frequently diagnosed in the elderly and middle-aged population. …”
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    Identification of the osteoarthritis signature gene PDK1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosis
  19. 3079
    “…SIMPLE SUMMARY: Osteoarthritis (OA) is a chronic progressive disease, which frequently requires lifelong therapy in dogs. …”
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    Physiotherapeutic Strategies and Their Current Evidence for Canine Osteoarthritis
  20. 3080
    “…The study aimed to explore the relationships between TB-BMD concentration and OA using Mendelian randomization (MR). METHODS: In this study, we used two-sample MR to obtain unconfounded estimates of the effect of TB-BMD on hip and knee OA. …”
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    The causal association between bone mineral density and risk of osteoarthritis: A Mendelian randomization study
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