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  1. 3141
    “…Modern diets low in n-3 PUFAs have been linked with increases in inflammatory disorders, possibly including OA. However, n-3 is also thought to increases bone density, which is a possible contributing factor in OA. …”
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    Regulation of osteoarthritis by omega-3 (n-3) polyunsaturated fatty acids in a naturally occurring model of disease
  2. 3142
    “…PURPOSE: An inflamed appendix can be removed either openly (open appendectomy [OA]) or laparoscopically (laparoscopic appendectomy [LA]). …”
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    Comparison of surgical-site infection between open and laparoscopic appendectomy
  3. 3143
    “…In the fracture group, 40/250 (16%) had a K&L OA grade II or higher, and in the contusion group 20/112 (18%) persons had a K&L OA grade II or higher (p = 0.66). …”
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    The rate of hip osteoarthritis in patients with proximal femoral fractures versus hip contusion
  4. 3144
    “…INTRODUCTION: The authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA. …”
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    Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study
  5. 3145
    “…Osteoarthritis (OA) is a common disease in the elderly due to an imbalance in cartilage degradation and synthesis. …”
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    Procyanidin B3 Prevents Articular Cartilage Degeneration and Heterotopic Cartilage Formation in a Mouse Surgical Osteoarthritis Model
  6. 3146
    “…The development of a serological marker for early diagnosis of isocyanate-induced occupational asthma (isocyanate-OA) may improve clinical outcome. Our previous proteomic study found that expression of vitamin D-binding protein (VDBP) was upregulated in the patients with isocyanate-OA. …”
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    Role of vitamin D-binding protein in isocyanate-induced occupational asthma
  7. 3147
    “…The present study investigated the chronic efficacy of oleanolic acid (OA), a triterpenoid selected from our recent screening, on hyperglycemia in type-2 diabetic mice. …”
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    Oleanolic Acid Reduces Hyperglycemia beyond Treatment Period with Akt/FoxO1-Induced Suppression of Hepatic Gluconeogenesis in Type-2 Diabetic Mice
  8. 3148
    “…BACKGROUND: The tumor necrosis factor (TNF) is believed to play an important role in the pathophysiology of osteoarthritis (OA). Evidence shows that genetic polymorphisms make substantial contributions to the etiology of OA. …”
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    TNF-α and TNF-β Polymorphisms are Associated with Susceptibility to Osteoarthritis in a Korean Population
  9. 3149
    “…Gross appearance of OA was evaluated on 29 left knees after dissection and India ink staining of tibial plateaus. …”
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    Chondrocalcinosis of Femoro-Tibial and Proximal Tibio-Fibular Joints in Cadaveric Specimens: A High-Resolution CT Imaging Study of the Calcification Distribution
  10. 3150
    “…Monosodium -iodoacetate (MIA)-induced animal model of osteoarthritis (OA) is under-utilised despite having many inherent advantages. …”
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    Histology, Glycosaminoglycan Level and Cartilage Stiffness in Monoiodoacetate-Induced Osteoarthritis: Comparative Analysis with Anterior Cruciate Ligament Transection in Rat Model and Human Osteoarthritis
  11. 3151
    “…INTRODUCTION: Our recent study indicated that subchondral bone pathogenesis in osteoarthritis (OA) is associated with osteocyte morphology and phenotypic abnormalities. …”
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    Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: role of integrinβ1 and focal adhesion kinase signaling cues
  12. 3152
    “…OBJECTIVE: To identify osteoarthritis (OA) relevant genes and pathways in damaged and undamaged cartilage isolated from the knees of patients with anteromedial gonarthrosis (AMG) – a specific form of knee OA. …”
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    A gene expression study of normal and damaged cartilage in anteromedial gonarthrosis, a phenotype of osteoarthritis
  13. 3153
    “…OBJECTIVE: Identify gene expression profiles associated with OA processes in articular cartilage and determine pathways changing during the disease process. …”
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    Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study
  14. 3154
    por Shen, Jin-Ming, Feng, Lei, Feng, Chun
    Publicado 2014
    “…BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis and has become an increasingly important public-health problem. …”
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    Role of mtDNA Haplogroups in the Prevalence of Osteoarthritis in Different Geographic Populations: A Meta-Analysis
  15. 3155
    “…OA also induced autophagy, which was a critical inducer of apoptosis in mild steatosis induced by 400 μM OA, but not in the more severe steatosis induced by 800 and 1200 μM OA. p53 inhibition by siRNA mostly blocked OA-induced apoptosis and autophagy. …”
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    Depending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM-induced autophagy or BAX
  16. 3156
    “…Here, the effect as well as mechanism of oleanolic acid (OA), a pentacyclic triterpenoid, on NSC function was investigated. …”
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    Oleanolic Acid Induces Differentiation of Neural Stem Cells to Neurons: An Involvement of Transcription Factor Nkx-2.5
  17. 3157
    “…To estimate the consultation incidence of OA using population-based health care data in England and compare OA incidence figures with those derived in other countries. …”
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    Annual consultation incidence of osteoarthritis estimated from population-based health care data in England
  18. 3158
    “…INTRODUCTION: Osteoarthritis (OA) is the most common age-related joint disease affecting >80% people beyond 55 years of age. …”
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    Effects of Osteoarthritis on Quality of life in Elderly Population of Bhubaneswar, India: A Prospective Multicenter Screening and Therapeutic Study of 2854 Patients
  19. 3159
    “…The correct and early diagnosis of OA is of great preventive and socio-economic importance. …”
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    Prevalence of Work-Related Asthma in Primary Health Care: Study Rationale and Design
  20. 3160
    “…In both instances, expression of the OA‐associated allele was reduced. In addition, there was reduced enhancer activity of the OA‐associated allele of rs116855380, a SNP in perfect LD with rs6094710 in luciferase assays (P < 0.001). …”
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    Correlation of the Osteoarthritis Susceptibility Variants That Map to Chromosome 20q13 With an Expression Quantitative Trait Locus Operating on NCOA3 and With Functional Variation at the Polymorphism rs116855380
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