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3301“…However, little is known about how treatment with OA affect the brain in chronic pain patients. Gaining this knowledge is a necessary first step towards understanding OA associated analgesia and elucidating long-term risk of OA misuse. …”
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3302“…Osteoarthritis (OA) is a chronic health condition. MicroRNAs (miRs) are critical in chondrocyte apoptosis in OA. …”
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3303por Nam, Jiho, Seol, Dong-Won, Lee, Choong-Gu, Wee, Gabbine, Yang, Siyoung, Pan, Cheol-Ho“…Osteoarthritis (OA) is an age-related degenerative disease that causes cartilage dysfunction and inflammation. …”
Publicado 2021
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3304por Wei, Yulong, Yan, Lesan, Luo, Lijun, Gui, Tao, Jang, Biang, Amirshaghaghi, Ahmad, You, Tianyan, Tsourkas, Andrew, Qin, Ling, Cheng, Zhiliang“…Treating osteoarthritis (OA) remains a major clinical challenge. Despite recent advances in drug discovery and development, no disease-modifying drug for knee OA has emerged with any notable clinical success, in part, due to the lack of valid and responsive therapeutic targets and poor drug delivery within knee joints. …”
Publicado 2021
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3305“…Further, key genes for RA and OA were obtained by combined analysis with differentially expressed genes (DEGs) between RA and OA in GSE56409 dataset. …”
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3306por Masud, Saad, Sheehan, Brendan, Rousseau-Saine, Alexis, Tucker, Allison, Sandman, Emilie, Wong, Ivan, Woodmass, Jarret, Chalal, Jas, Lobo, Joel, Grant, John, LeBel, Marie-Eve, Sommerfeldt, Mark, Kopka, Michaela, Urquhart, Nathan, Carsen, Sasha, Pauyo, Thierry, Khan, Moin“…BACKGROUND: Exercise is widely regarded to improve pain and function in patients with knee osteoarthritis (OA) through building supportive muscle mass, facilitating weight loss, and through the other beneficial effects associated with it. …”
Publicado 2021
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3307por Chien, Jia-Ying, Lin, Shu-Fang, Chou, Yu-Yau, Huang, Chi-Ying F., Huang, Shun-Ping“…A previous study showed that OA promotes retinal ganglion cell (RGC) survival after optic nerve (ON) crush injury. …”
Publicado 2021
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3308por Ingale, Dhanashri, Kulkarni, Priya, Electricwala, Ali, Moghe, Alpana, Kamyab, Sara, Jagtap, Suresh, Martson, Aare, Koks, Sulev, Harsulkar, Abhay“…Considering non-linear nature of cartilage loss in OA, a better understanding of inflammatory milieu and MMP status at different stages of OA is required to design early-stage therapies or personalized disease management. …”
Publicado 2021
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3309por Tyurin, Anton, Shapovalova, Daria, Gantseva, Halida, Pavlov, Valentin, Khusainova, Rita“…Over the past decades, numerous studies on the genetic markers of osteoarthritis (OA) have been conducted. MiRNA targets sites are a promising new area of research. …”
Publicado 2021
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3310por Jiang, Lejian, Lin, Jiachen, Zhao, Sen, Wu, Jiaqian, Jin, Yongming, Yu, Li, Wu, Nan, Wu, Zhihong, Wang, Yue, Lin, Mao“…ADAMTS5 is involved in the pathogenesis of OA. As the major aggrecanase-degrading articular cartilage matrix, ADAMTS5, has been regarded as a potential target for OA treatment. …”
Publicado 2021
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3311Epidemiological Characteristics of Osteoarthritis in Yichang City — Hubei Province, China, 2017–2018“…WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? OA has been listed as the fastest increasing major public health problem and ranked second as a cause of disability by World Health Organization (WHO). …”
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3312por Liang, Yulin, Xu, Ke, Liu, Wenguang, Liu, Xiaoling, Yuan, Ping, Xu, Peng, Li, Haiyun“…Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage degeneration and secondary bone hyperplasia. …”
Publicado 2022
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3313por Yeo, Changhwan, Ahn, Chae Ryeong, Kim, Jai-Eun, Kim, Young Woo, Park, Jinbong, Ahn, Kwang Seok, Ha, In Jin, Lee, Yoon Jae, Baek, Seung Ho, Ha, In-Hyuk“…Osteoarthritis (OA) causes persistent pain, joint dysfunction, and physical disability. …”
Publicado 2022
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3314por Lombardi, Alecio F., Ma, Yajun, Jang, Hyungseok, Jerban, Saeed, Tang, Qingbo, Searleman, Adam C., Meyer, Robert Scott, Du, Jiang, Chang, Eric Y.“…A relationship between an acidic pH in the joints, osteoarthritis (OA), and pain has been previously demonstrated. …”
Publicado 2022
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3315por Yu, Ruixue, Yang, Wenqing, Qi, Dongmei, Gong, Lili, Li, Chao, Li, Yunlun, Jiang, Haiqiang“…Studies have shown that oleanolic acid (OA) can effectively regulate neurotransmitter-related metabolic disorders caused by EH, but the mechanism is still unclear. …”
Publicado 2019
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3316“…Introduction Osteoarthritis (OA) of the knee is a common complaint in the elderly population and results in considerable disability in advanced stages. …”
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3317por Pertusa, Clara, Mifsut, Damián, Morales, José Manuel, Tarín, Juan J., Cano, Antonio, Monleón, Daniel, García-Pérez, Miguel Ángel“…Bone pathologies such as osteoporosis (OTP) and osteoarthritis (OA) are rising in incidence with the worldwide rise in life expectancy. …”
Publicado 2022
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3318“…The inflammatory environment of osteoarthritis (OA) inhibits the repair ability of CPCs. But the OA patients' CPCs showed an excellent regeneration ability with intermittent hydrostatic pressure (IHP). …”
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3319“…Risk factors for osteoarthritis (OA) often exert effects over protracted time-courses. …”
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3320“…OBJECTIVE: To conduct a network meta-analysis comparing all treatments for osteoarthritis (OA) pain in the Cochrane Library. DESIGN: The Cochrane Library and Epistemonikos were searched for randomized controlled trials (RCTs) about treatments for hip and knee OA. …”
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