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  1. 3461
    “…Strategies for treating osteoarthritis (OA) have become a research focus because an effective treatment for OA is unavailable. …”
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    Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways
  2. 3462
    “…This study aimed to identify the prevalence of sarcopenia, obesity, and sarcopenic obesity and examine their association with radiographic knee osteoarthritis (OA) and knee pain in Korean postmenopausal women. …”
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    Effects of sarcopenia and sarcopenic obesity on joint pain and degenerative osteoarthritis in postmenopausal women
  3. 3463
    “…The biogenic amine octopamine (OA) orchestrates many behavioural processes in insects. …”
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    Octopamine signaling via OctαR is essential for a well-orchestrated climbing performance of adult Drosophila melanogaster
  4. 3464
    “…Immune-related genes and immune cell infiltration play a crucial role in OA development. We used bioinformatics approaches to detect potential diagnostic markers and available drugs for OA while initially exploring the immune mechanisms of OA. …”
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    Identification of Potential Therapeutic Target Genes in Osteoarthritis
  5. 3465
    “…BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disease primarily characterized by cartilage destruction. …”
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    Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis
  6. 3466
    “…Moreover, when osteoarthritis (OA) was induced in Sprague Dawley rats via bilateral anterior cruciate ligament transection (ACLT), miR-451 expression was increased in OA cartilage compared to control, suggesting its inhibition might be used to prevent or treat OA. …”
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    Prophylactic administration of miR-451 inhibitor decreases osteoarthritis severity in rats
  7. 3467
    “…SIMPLE SUMMARY: Autologous conditioned serum (ACS) has benefits in managing osteoarthritis (OA) due to enriched mediators, including Interleukin-1 receptor antagonists (IL-1RA) and growth factors. …”
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    In Vitro Anti-Inflammatory and Regenerative Effects of Autologous Conditioned Serum from Dogs with Osteoarthritis
  8. 3468
    “…BACKGROUND: Lower back pain (LBP) and osteoarthritis (OA) are common musculoskeletal disorders and account for around 17.0% of years lived with disability worldwide; however, there is a lack of real-world data on these conditions. …”
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    Paracetamol Use in Patients With Osteoarthritis and Lower Back Pain: Infodemiology Study and Observational Analysis of Electronic Medical Record Data
  9. 3469
    por Yu, Xiaoyuan, Zhao, Li, Song, Bin
    Publicado 2022
    “…OBJECTIVE: A retrospective clinical study was conducted to compare the prognosis between the opioid analgesic (OA) treated and OA-untreated groups and to evaluate the effect of opioid analgesics on the efficacy of immune checkpoint inhibitors (ICIs) in the treatment of advanced lung cancer patients. …”
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    Impact of opioid analgesics on the efficacy of immune checkpoint inhibitors in a lung cancer population
  10. 3470
    “…Osteoarthritis (OA) causes intestinal damage. The protective effect of probiotics on the intestine is indeed effective; however, the mechanism of protection against intestinal damage in OA is not clear. …”
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    Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by improving fecal microbiome metabolism and enhancing the colonic barrier
  11. 3471
    “…SIMPLE SUMMARY: Osteoarthritis (OA) is a common and disabling condition affecting half billion people worldwide. …”
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    Molecular Characterization of Secreted Factors and Extracellular Vesicles-Embedded miRNAs from Bone Marrow-Derived Mesenchymal Stromal Cells in Presence of Synovial Fluid from Osteoarthritis Patients
  12. 3472
    “…Despite the high prevalence of osteoarthritis (OA) in older populations, disease-modifying OA drugs (DMOADs) are still lacking. …”
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    The natural product salicin alleviates osteoarthritis progression by binding to IRE1α and inhibiting endoplasmic reticulum stress through the IRE1α-IκBα-p65 signaling pathway
  13. 3473
    “…In a previous study, we found that the expression of circStrn3 was significantly reduced in chondrocytes of osteoarthritis (OA) patients and OA mice. Therefore, the aim of this paper was to explore the role and mechanism of circStrn3 in osteoarthritis. …”
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    CircStrn3 targeting microRNA-9-5p is involved in the regulation of cartilage degeneration and subchondral bone remodelling in osteoarthritis
  14. 3474
    “…Introduction Osteoarthritis (OA) of the knee is a common degenerative disease, relatively more prevalent among middle-aged people. …”
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    Comparison of Various Modalities in the Treatment of Early Knee Osteoarthritis: An Unsolved Controversy
  15. 3475
    “…OA-PSV and OA-EDV values were significantly lower in the amblyopic eye than in the healthy eye (p < 0.05). …”
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    Retrobulbar Blood Flow Parameters in Patients With Anisometropic Amblyopia
  16. 3476
    “…OBJECTIVES: The aim of this study was to investigate central sensitization and associated factors in knee osteoarthritis (OA) patients and compare them with rheumatoid arthritis (RA) patients and healthy controls. …”
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    Central sensitization in osteoarthritic knee pain: A cross-sectional study
  17. 3477
    “…Osteoarthritis (OA) is a prevalent form of arthritis that affects over 32.5 million adults worldwide, causing significant cartilage damage and disability. …”
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    Chondrocyte Thrombomodulin Protects against Osteoarthritis
  18. 3478
    “…Osteoarthritis (OA) is the most common degenerative joint disease in the world. …”
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    Urchin-like ceria nanoparticles for enhanced gene therapy of osteoarthritis
  19. 3479
    “…Osteoarthritis (OA) is one of the most common chronic diseases in the world. …”
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    GPRC5B protects osteoarthritis by regulation of autophagy signaling
  20. 3480
    “…PURPOSE: Recent scientific reports have revealed a close association between ferroptosis and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise mechanisms by which ferroptosis influences OA and how to hobble OA progression by inhibiting chondrocyte ferroptosis have not yet been fully elucidated. …”
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    Crosstalk between ferroptosis and chondrocytes in osteoarthritis: a systematic review of in vivo and in vitro studies
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