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  1. 3581
    por Mattos, Meghan, Lingler, Jennifer
    Publicado 2021
    “…The third presentation features recruitment adaptations for an Internet-delivered behavioral intervention study with oaMCI and insomnia. Anticipated concerns of oaMCI using technology or accessing the Internet were not significant barriers to recruitment, while fewer oaMCI endorsed sleep concerns than expected. …”
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    Recruiting Eligible and Interested Study Participants With Cognitive Impairment
  2. 3582
    “…In recent years, several nutraceutical interventions have been investigated in order to define better solutions for preventing and treating OA. Among them, polyunsaturated fatty acids (n-3 PUFAs) appear to represent potential candidates in counteracting OA and its consequences, due to their anti-inflammatory, antioxidant, and chondroinductive effects. …”
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    The Role of Nutraceuticals in Osteoarthritis Prevention and Treatment: Focus on n-3 PUFAs
  3. 3583
    “…Osteoarthritis (OA) is the most commonly observed arthritic disease causing severe pain and impairing patient's quality of life. …”
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    Comparison of Elaeagnus angustifolia L. extract and quercetin on mouse model of knee osteoarthritis
  4. 3584
    “…Suppressed level of ACOT12 was observed in cartilages of OA patient and OA-induced animal. To determine the role and association of ACOT12 in the OA pathogenesis, we generated Acot12 knockout (KO) (Acot12(−/−)) mice using RNA-guided endonuclease. …”
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    PPARα−ACOT12 axis is responsible for maintaining cartilage homeostasis through modulating de novo lipogenesis
  5. 3585
    “…In this study, we used monoiodoacetate (MIA)-induced OA in male rats to test the idea that pain in OA is driven by differential contributions from nerves that innervate knee joint articular tissues vs the surrounding bone. …”
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    Changes to the activity and sensitivity of nerves innervating subchondral bone contribute to pain in late-stage osteoarthritis
  6. 3586
    “…Osteoarthritis (OA) is a common degenerative disease in middle-aged and elderly people. …”
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    miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway
  7. 3587
    “…OBJECTIVE: Biomarkers in osteoarthritis (OA) could serve as objective clinical indicators for various disease parameters, and act as surrogate endpoints in clinical trials for disease-modifying drugs. …”
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    Clinically Relevant Molecular Biomarkers for Use in Human Knee Osteoarthritis: A Systematic Review
  8. 3588
    “…BACKGROUND: To explore the effects of type 2 diabetes mellitus (T2DM) on osteoarthritis (OA), 12 bone tissue samples were obtained surgically from the human total knee arthroplasty patients and analyzed by quantitative proteomics. …”
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    Data-independent acquisition-based proteomics analysis correlating type 2 diabetes mellitus with osteoarthritis in total knee arthroplasty patients
  9. 3589
    “…Aging and mechanical overload are prominent risk factors for osteoarthritis (OA), which lead to an imbalance in redox homeostasis. …”
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    Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis
  10. 3590
    “…RESULTS: The inhibitory effect of OA was observed in the critical cellular processes of HBV-associated HCC cells, which depend on OA concentration. …”
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    Downregulated lncRNA SNHG18 Suppresses the Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma and Meditates the Antitumor Effect of Oleanolic Acid
  11. 3591
    “…Additionally, WB is also used as a supplement to the treatment of osteoarthritis (OA) in clinical practice. Our research aimed to reveal the therapeutic effects and underling mechanism of WB on RA and OA through computational system pharmacology analysis and experimental study. …”
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    Network Pharmacology-Based Analysis on the Effects and Mechanism of the Wang-Bi Capsule for Rheumatoid Arthritis and Osteoarthritis
  12. 3592
    por Sun, Peng, Xue, Yuan
    Publicado 2022
    “…However, its function in osteoarthritis (OA) has not yet been determined. This study aims to reveal the role of TBK1 in the extracellular matrix (ECM) degradation in OA. …”
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    Silence of TANK-binding kinase 1 (TBK1) regulates extracellular matrix degradation of chondrocyte in osteoarthritis by janus kinase (JAK)-signal transducer of activators of transcription (STAT) signaling
  13. 3593
    “…PURPOSE: Thumb carpometacarpal (CMC) osteoarthritis (OA) is a prevalent disease that causes pain and disability. …”
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    Radiographic Progression of Thumb CMC Osteoarthritis: A Systematic Review
  14. 3594
    por Zhang, Shuai, Jin, Zhe
    Publicado 2022
    “…However, an extensive investigation of the mechanism of BMSC-derived EVs (BMSC-EVs) in osteoarthritis (OA) remains unknown. Thus, we focused on the mechanism behind BMSC-EVs in OA. …”
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    Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Containing Long Noncoding RNA NEAT1 Relieve Osteoarthritis
  15. 3595
    “…This study aims to investigate the significance of organizational ambidexterity (OA) in creating supply chain resilience (SCRES) during and after the COVID-19 pandemic. …”
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    Creating supply chain resilience during and post-COVID-19 outbreak: the organizational ambidexterity perspective
  16. 3596
    por Zhu, Bin, Wang, Xuejian, Teng, Jiawen
    Publicado 2018
    “…Osteoarthritis (OA) is the most common joint disease among late middle-aged or elderly people. …”
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    Retracted Article: Salvianolic acid B inhibits inflammatory response and cell apoptosis via the PI3K/Akt signaling pathway in IL-1β-induced osteoarthritis chondrocytes
  17. 3597
    “…BACKGROUND: Although there are many pharmacological interventions for adults with osteoarthritis (OA) who do not meet the indications for surgery, side effects and adverse effects cannot be ignored. …”
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    The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis
  18. 3598
    “…PURPOSE: To facilitate studies of knee osteoarthritis (OA) in large databases, case finding algorithms with high levels of diagnostic performance are needed. …”
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    Validation of knee osteoarthritis case identification algorithms in a large electronic health record database
  19. 3599
    “…BACKGROUND & OBJECTIVES: Osteoarthritis (OA) is the 11(th) leading cause of disability in the modern world, but till date, there have been no effective markers for monitoring the progression of OA. …”
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    Serum levels of osteoprotegerin, RANK-L & vitamin D in different stages of osteoarthritis of the knee
  20. 3600
    “…OBJECTIVE: To investigate the expression of Hedgehog (HH) signaling pathway proteins in knee articular cartilage from Kashin-Beck disease (KBD) and osteoarthritis (OA) patients. METHODS: Knee articular cartilage samples were collected from normal (N), OA, and KBD adults (aged 38-60 years) and divided into 3 groups with 6 subjects in each group. …”
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    Altered Expression of the Hedgehog Pathway Proteins BMP2, BMP4, SHH, and IHH Involved in Knee Cartilage Damage of Patients With Osteoarthritis and Kashin-Beck Disease
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