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  1. 1461
    “…PURPOSE: The triterpene oleanolic acid (OA) is known to possess antihypertensive actions. …”
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    Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals
  2. 1462
    “…Obesity is considered a major risk factor for the development and progression of knee osteoarthritis (OA). Apart from the mechanical effect of obesity via increase in mechanical overload of weight-bearing joints, an association with hand OA has been observed. …”
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    Serum Leptin and Resistin Levels in Knee Osteoarthritis—Clinical and Radiologic Links: Towards Precise Definition of Metabolic Type Knee Osteoarthritis
  3. 1463
    “…Therapeutic options for OA are limited, and the pathogenic mechanism of OA remains unclear. …”
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    Online Artículo Texto
    IL-17 in osteoarthritis: A narrative review
  4. 1464
    “…Occupational asthma (OA) is a heterogeneous disease, and the characteristics of the sensitizer responsible for OA may induce different clinical, functional, and biological manifestations. …”
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    Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma
  5. 1465
    “…Osteoarthritis (OA) might affect chondrocyte culture characteristics and complement expression. …”
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    Macroscopical, Histological, and In Vitro Characterization of Nonosteoarthritic Versus Osteoarthritic Hip Joint Cartilage
  6. 1466
    “…The present work aimed to assess the chondroprotective influence of chitosan and lecithin in a monoiodoacetate (MIA)-induced experimental osteoarthritis (OA) model. Forty male rats weighing 180–200 g were randomly distributed among the following five experimental groups (eight per group): control, MIA-induced OA, MIA-induced OA + chitosan, MIA-induced OA + lecithin, and MIA-induced OA + chitosan + lecithin. …”
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    Chitosan and Lecithin Ameliorate Osteoarthritis Symptoms Induced by Monoiodoacetate in a Rat Model
  7. 1467
    “…To reveal the pathogenesis of OA, 12 SD male rats were randomly divided into control and OA groups using collagenase to induce OA for modeling, and serum was collected 7 days after modeling for testing. …”
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    Analysis of Serum Metabolomics in Rats with Osteoarthritis by Mass Spectrometry
  8. 1468
    por Zhai, Guangju
    Publicado 2021
    “…OBJECTIVES: A narrative review on recent published studies of metabolomics in osteoarthritis (OA) with the focus on how the metabolomic findings help stratify OA patients in precision medicine. …”
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    The role of metabolomics in precision medicine of osteoarthritis: How far are we?
  9. 1469
    “…Pain, the primary symptom of osteoarthritis (OA), reduces both the quality and quantity of life for patients. …”
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    Mechanisms of Peripheral and Central Sensitization in Osteoarthritis Pain
  10. 1470
    por Tan, Zhe, Chen, Rong, Lin, Hanyu, Wang, Hong
    Publicado 2023
    “…Osteoarthritis (OA) is a chronic musculoskeletal disease affecting approximately 500 million people worldwide. …”
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    The Identification of Immune-Related Biomarkers for Osteoarthritis Immunotherapy Based on Single-Cell RNA Sequencing Analysis
  11. 1471
    “…Development of OA (OA) is multifactorial and is strongly associated with risk factors such as aging, trauma, metabolic disorders, and obesity. …”
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    Biomarkers of Osteoarthritis—A Narrative Review on Causal Links with Metabolic Syndrome
  12. 1472
    por Kaczer, Laura, Maldonado, Héctor
    Publicado 2009
    “…BACKGROUND: Biogenic amines are implicated in reinforcing associative learning. Octopamine (OA) is considered the invertebrate counterpart of noradrenaline and several studies in insects converge on the idea that OA mediates the reward in appetitive conditioning. …”
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    Contrasting Role of Octopamine in Appetitive and Aversive Learning in the Crab Chasmagnathus
  13. 1473
    “…According to this difference, we may conclude that uCTX-II can be a biomarker for OA diagnosis. METHODS: We searched MEDLINE and EMBASE databases updated to 2014 to find literature on OA biomarkers. …”
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    Meta-analysis of urinary C-terminal telopeptide of type II collagen as a biomarker in osteoarthritis diagnosis
  14. 1474
    “…Osteoarthritis (OA) is the most common form of the joint disease associated with age, obesity, and traumatic injury. …”
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    Inflammation-Modulating Hydrogels for Osteoarthritis Cartilage Tissue Engineering
  15. 1475
    “…We have been studying mesenchymal stem cells (MSCs) in synovial fluid and the intra-articular injection of synovial MSCs in osteoarthritis (OA) knees. Here, mainly based on our own findings, we overview the characteristics of endogenous MSCs in the synovial fluid of OA knees and their mode of action when injected exogenously into OA knees. …”
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    Characteristics of MSCs in Synovial Fluid and Mode of Action of Intra-Articular Injections of Synovial MSCs in Knee Osteoarthritis
  16. 1476
    “…Chondrocyte hypertrophy is one of the key indicators in the progression of osteoarthritis (OA). However, compared with other OA indications, such as cartilage collapse, sclerosis, inflammation, and protease activation, the mechanisms by which chondrocyte hypertrophy contributes to OA remain elusive. …”
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    Functional Duality of Chondrocyte Hypertrophy and Biomedical Application Trends in Osteoarthritis
  17. 1477
    “…BACKGROUND AND PURPOSE: Several traditional risk factors of atherosclerosis such as age, obesity, and altered lipid metabolism are shared with osteoarthritis (OA). Metabolic abnormalities and atheromatous vascular disease are linked with systemic inflammation and progression of OA. …”
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    Prevention of Osteoarthritis Progression by Statins, Targeting Metabolic and Inflammatory Aspects: A Review
  18. 1478
    “…Joint pain is the hallmark symptom of osteoarthritis (OA) and the main reason for patients to seek medical assistance. …”
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    Osteoarthritis Pain
  19. 1479
    “…The key step for biofilm formation is C. albicans ability to transit from yeast to hypha (filamentation). Since oleic acid (OA), a natural compound, prevents filamentation, we modified PMMA with OA aiming the antifungal PMMA_OA materials. …”
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    Poly(methyl methacrylate) with Oleic Acid as an Efficient Candida albicans Biofilm Repellent
  20. 1480
    “…To date, several in vivo models have been used to reproduce the onset and monitor the progression of osteoarthritis (OA), and guinea pigs represent a standard model for studying naturally occurring, age-related OA. …”
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    Naturally Occurring Osteoarthritis Features and Treatments: Systematic Review on the Aged Guinea Pig Model
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