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  1. 1841
    “…The aim of this study is to investigate the supportive effects of MSCs on OA chondrocytes and test if FGF18 could enhance the responsiveness of OA chondrocytes to the support of MSCs in a coculture system. …”
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    Fibroblast Growth Factor 18 Increases the Trophic Effects of Bone Marrow Mesenchymal Stem Cells on Chondrocytes Isolated from Late Stage Osteoarthritic Patients
  2. 1842
    “…The cytokine interleukin 1β (IL-1β) was also used to simulate an in vitro OA model. METHODS: Normal and OA chondrocytes were cultured in monolayer and analyzed for changes in cartilage-specific gene expressions due to passage number. …”
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    Evaluating Osteoarthritic Chondrocytes through a Novel 3-Dimensional In Vitro System for Cartilage Tissue Engineering and Regeneration
  3. 1843
    “…MATERIAL/METHODS: A total of 37 knee OA patients and 20 healthy controls were enrolled in this study. …”
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    Correlation of Bone Morphogenetic Protein-2 Levels in Serum and Synovial Fluid with Disease Severity of Knee Osteoarthritis
  4. 1844
    “…The immunoexpression and the mRNA levels of lubricin increased in normal cartilage and decreased in OA cartilage (normal vs. OA, p < 0.01). By contrast, the immunoexpression and the mRNA levels of CHI3L1 increased in OA cartilage and decreased in normal cartilage (normal vs. …”
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    Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles
  5. 1845
    “…Maternal OA stress resulted in eggs with lower carbon content, while embryonic OA stress retarded development. …”
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    Pteropod eggs released at high pCO(2) lack resilience to ocean acidification
  6. 1846
    “…The monoamines octopamine (OA) and tyramine (TA) modulate numerous behaviours and physiological processes in invertebrates. …”
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    Octopamine controls starvation resistance, life span and metabolic traits in Drosophila
  7. 1847
    “…Osteoarthritis (OA) is a degenerative disorder characterized by chondrocyte apoptosis and degeneration of articular cartilage resulting in loss of mobility and pain. …”
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    Enumeration and Localization of Mesenchymal Progenitor Cells and Macrophages in Synovium from Normal Individuals and Patients with Pre-Osteoarthritis or Clinically Diagnosed Osteoarthritis
  8. 1848
    “…Osteoarthritis (OA) is a complex disease that affects the whole joint, resulting from the combined influence of biomechanical factors and genetic factors. …”
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    Association between EN1 rs4144782 and susceptibility of knee osteoarthritis: A case-control study
  9. 1849
    por Ding, Jian, Niu, Xin, Su, Yan, Li, Xiaolin
    Publicado 2017
    “…In the present study, the levels of synovial fluid biomarkers of patients with knee osteoarthritis (OA) and those with meniscus injury (MI) were compared to associate the levels of synovial fluid biomarkers with the degree of OA and MI. …”
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    Expression of synovial fluid biomarkers in patients with knee osteoarthritis and meniscus injury
  10. 1850
    por Lu, Yuan-Fu, Wan, Xiao-Li, Xu, Yasha, Liu, Jie
    Publicado 2013
    “…Oleanolic acid (OA) is a triterpenoid and a fantastic molecule with many beneficial effects. …”
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    Repeated Oral Administration of Oleanolic Acid Produces Cholestatic Liver Injury in Mice
  11. 1851
    “…The phenotypic change of chondrocytes and the interplay between cartilage and subchondral bone in osteoarthritis (OA) has received much attention. Structural changes with nerve ingrowth and vascular penetration within OA cartilage may contribute to arthritic joint pain. …”
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    Systematic Analysis of Transcriptomic Profile of Chondrocytes in Osteoarthritic Knee Using Next-Generation Sequencing and Bioinformatics
  12. 1852
    “…In the present study, we investigated the role of IL-6 in osteoarthritis (OA) patients and the effects of the stilbenoids monomethyl pinosylvin and pinosylvin on the expression of the cartilage matrix components aggrecan and collagen II and the inflammatory cytokine IL-6 in human OA chondrocytes. …”
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    IL-6 in Osteoarthritis: Effects of Pine Stilbenoids
  13. 1853
    “…AIM: This paper reports on the incorporation of oleic acid (OA) within nanostructured lipid carriers (OA-NLC) to improve the anti-inflammatory effects in the presence of albumin. …”
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    Oleic acid-loaded nanostructured lipid carrier inhibit neutrophil activities in the presence of albumin and alleviates skin inflammation
  14. 1854
    “…Osteoarthritis (OA) is the most frequent joint disease; however, the etiopathogenesis is still unclear. …”
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    Impaired Metabolic Flexibility in the Osteoarthritis Process: A Study on Transmitochondrial Cybrids
  15. 1855
    “…Osteoarthritis (OA) is the most common joint disorder in the United States, and the gut microbiome has recently emerged as a potential etiologic factor in OA development. …”
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    Identification and Characterization of the Intra-Articular Microbiome in the Osteoarthritic Knee
  16. 1856
    “…PURPOSE: Previous studies reported the relation of osteoarthritis (OA) and hypertension (HTN) mostly in postmenopausal women. …”
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    Association of the Risk of Osteoarthritis and Hypertension in the Korean Adult Population Aged 40–59 in Pre- and Postmenopausal Women: Using Korea National Health and Nutrition Examination Survey 2012–2016 Data
  17. 1857
    “…Osteoarthritis (OA) is the leading cause of function loss and disability among the elderly, with significant burden on the individual and society. …”
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    New Trends in Pharmacological Treatments for Osteoarthritis
  18. 1858
    “…Osteoarthritis (OA) had a high incidence in people over 65 years old, and there is currently no drug that could completely cure it. …”
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    Mesenchymal Stem Cell-Derived Exosomes Modulate Chondrocyte Glutamine Metabolism to Alleviate Osteoarthritis Progression
  19. 1859
    “…Oleanolic acid (OA), a bioactive ingredient of Panax ginseng, exhibits neuroprotective pharmacological effects. …”
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    Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway
  20. 1860
    “…Osteoarthritis (OA) is a chronic degenerative joint disease characterized by progressive cartilage loss, subchondral bone remodeling, and synovial inflammation. …”
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    Unbiased transcriptome mapping and modeling identify candidate genes and compounds of osteoarthritis
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