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  1. 461
    “…Among the three formulations, RD1 showed the highest percentage of drug release. Ex vivo drug diffusion studies were conducted on freshly excised sheep nasal mucosa with Franz diffusion cell simulated nasal fluid (SNF) for all three formulations up to 6 h, and the thermotriggered nanoemulsion (RD1) showed 71.42% drug release with 42.64 nm particle size and a poly dispersity index of 0.354. …”
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    Formulation of Intranasal Mucoadhesive Thermotriggered In Situ Gel Containing Mirtazapine as an Antidepressant Drug
  2. 462
    “…Also, F1 showed a higher rate of late apoptosis than the pure drug and the corresponding non-medicated formulation. …”
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    Exploring the Enhanced Antiproliferative Activity of Turmeric Oil and 6-Mercaptopurine in a Combined Nano-Particulate System Formulation
  3. 463
    Publicado 1993
    “…As compared to strongly bound S1, weakly bound S1 showed a significantly broader distribution of attachment angles. …”
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    Time-resolved electron microscopic analysis of the behavior of myosin heads on actin filaments after photolysis of caged ATP
  4. 464
    “…Marek’s disease virus type 1 (MDV-1) shows a strict dependency on the direct cell-to-cell spread for its propagation in cell culture. …”
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    The Marek’s disease virus (MDV) protein encoded by the UL17 ortholog is essential for virus growth
  5. 465
    por Kleidon, Axel
    Publicado 2012
    “…The Earth's chemical composition far from chemical equilibrium is unique in our Solar System, and this uniqueness has been attributed to the presence of widespread life on the planet. Here, I show how this notion can be quantified using non-equilibrium thermodynamics. …”
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    How does the Earth system generate and maintain thermodynamic disequilibrium and what does it imply for the future of the planet?
  6. 466
    por Roberts, Gilbert
    Publicado 2013
    “…In contrast to previous models suggesting punishment is disadvantaged when rare, I show it can invade until it comes into a producer-scrounger equilibrium with non-punishers. …”
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    When Punishment Pays
  7. 467
    “…LmGSTd1, LmGSTs5, and LmGSTu1 showed high activities with 1-chloro-2, 4-dinitrobenzene (CDNB), detectable activity with p-nitro-benzyl chloride (p-NBC) and 1, 2-dichloro-4-nitrobenzene (DCNB), whereas LmGSTt1 showed high activity with p-NBC and detectable activity with CDNB. …”
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    Characterization and Functional Analysis of Four Glutathione S-Transferases from the Migratory Locust, Locusta migratoria
  8. 468
    “…Optical coherence tomography (OCT) showed considerable amelioration of retinal swelling and CME. MP-1 showed a marked increase of foveal sensitivity. However, she had recurrence of edema 3 months later. …”
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    Unilateral macular edema with central retinal vein occlusion in systemic lupus erythematosus: a case report
  9. 469
    “…Promastigotes lacking one LMIT1 allele (LMIT1/Δlmit1) showed growth defects and were more susceptible to ROS toxicity, consistent with the role of iron as the essential co-factor of trypanosomatid mitochondrial superoxide dismutases. …”
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    A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence
  10. 470
    “…Apoptosis and proliferation were monitored to examine the cellular effect of Rh2. RESULTS: LINE1 showed induction of hypomethylation at specific CpGs by 1.6–9.1% (p < 0.05). …”
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    Ginsenoside Rh2 epigenetically regulates cell-mediated immune pathway to inhibit proliferation of MCF-7 breast cancer cells
  11. 471
    por Parashar, Shomini, Kumar, Narendra
    Publicado 2018
    “…“CGIPL 1” showed maximum activity at pH 9 while “SELA 2” and “SELA 4” showed maximum activity at pH 5. …”
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    Studies on agarolytic bacterial isolates from agricultural and industrial soil
  12. 472
    “…The crystal structure of 1 shows that the trimeric unit {Co(3)(μ(3)-OH)(COO)(5)N(3)} and monomeric unit {Co(COO)(2)(NC(5)H(4))(2)}(2+) are linked with BTB and BPE linkers to form a three-dimensional structure. …”
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    Cobalt-Based Coordination Polymer for Oxygen Reduction Reaction
  13. 473
    “…At the end of the third month, Group I showed 96% clinical and radiographical success, Group II showed 100% clinical and 96% radiographical success, and Group III showed 100% clinical and radiographical success. …”
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    Evaluation of the Clinical and Radiological Outcomes of Pulpotomized Primary Molars Treated with Three Different Materials: Mineral Trioxide Aggregate, Biodentine, and Pulpotec. An In-vivo Study
  14. 474
    “…Similar to thermophilic F(1), bMF(1) showed a strong exponential increase in ATP affinity, while the hydrolysis equilibrium did not change significantly. …”
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    Rotary catalysis of bovine mitochondrial F(1)-ATPase studied by single-molecule experiments
  15. 475
    “…YRNAs were significantly upregulated in T4 stage. YRNA1 showed the highest sensitivity, allowing to distinguish healthy from cancer tissue. …”
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    YRNAs: New Insights and Potential Novel Approach in Head and Neck Squamous Cell Carcinoma
  16. 476
    “…To measure the impact of the forest environment on the level of procrastination of the subjects, a randomized experiment was carried out, in which the subjects watched in random order (on different days) one of two 15-min videos: one showing a walk in the forest area and one showing a walk in an urban environment (control). …”
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    Effect of Viewing Video Representation of the Urban Environment and Forest Environment on Mood and Level of Procrastination
  17. 477
    por Liu, Xinping, Deng, Wei, Yang, Yang
    Publicado 2021
    “…The enzymatic properties of LAC-Yang1 and its ability to degrade and detoxify chlorophenols such as 2,6-dichlorophenol and 2,3,6-trichlorophenol were systematically studied. LAC-Yang1 showed a strong tolerance to extremely acidic conditions and strong stability under strong alkaline conditions (pH 9–12). …”
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    Characterization of a Novel Laccase LAC-Yang1 from White-Rot Fungus Pleurotus ostreatus Strain Yang1 with a Strong Ability to Degrade and Detoxify Chlorophenols
  18. 478
    “…Compared to the NS group, patients with PARA-I showed significant differences in the hysteria and hypomania subscales (P<.05) and patients with PSY-I showed significant differences in the hysteria, hypochondriasis, and psychopathic subscales (P=.001). …”
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    Personality profiles in paradoxical insomnia: a case-control study
  19. 479
    por Archetti, Marco
    Publicado 2021
    “…SIMPLE SUMMARY: Using experiments in vitro and a mathematical model, I show that genetically modified cancer cells in which the gene for an essential growth factor is knocked out can spread in a population of cells that produce that growth factor, leading to an overall reduction in proliferation—a proof of principle for a potential treatment that harnesses clonal selection by impairing intra-tumor cooperation. …”
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    Collapse of Intra-Tumor Cooperation Induced by Engineered Defector Cells
  20. 480
    “…Furthermore, an increase in surface roughness was observed following bleaching, with Group B1 showing maximum percentage increase (14.80%), followed by Group B2 (8.25%) and Group B3 (5.79%). …”
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    A comparative evaluation of the effect of three different concentrations of in-office bleaching agents on microhardness and surface roughness of enamel – An in vitro study
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