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9881por Pan, Lili, Su, Zhe, Song, Jianming, Xu, Wanhua, Liu, Xia, Zhang, Longjiang, Li, Shoulin“…Nineteen patients exhibited ambiguous genitalia, 12 had short stature, and 1 showed a lack of breast development. Seventeen patients were raised as males, and 15 were raised as females. …”
Publicado 2019
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9882“…Knockdown of DLX6-AS1 showed an opposite effect in all the experiments. miR-497-5p was demonstrated to be a direct target of DLX6-AS1 and was regulated by DLX6-AS1. …”
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9883“…On a method comparison, Trop-I showed good agreement, yielding a kappa value of 0.95. …”
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9884por Venugopala, Katharigatta Narayanaswamy, Chandrashekharappa, Sandeep, Pillay, Melendhran, Abdallah, Hassan H., Mahomoodally, Fawzi M., Bhandary, Subhrajyoti, Chopra, Deepak, Attimarad, Mahesh, Aldhubiab, Bandar E., Nair, Anroop B., Sreeharsha, Nagaraja, Morsy, Mohamed A., Pottathil, Shinu, Venugopala, Rashmi, Odhav, Bharti, Mlisana, Koleka“…In silico studies showed binding affinity within the range of 7.07–8.57 kcal/mol, with 5i showing the highest binding affinity. Hydrogen bonding, π-π- interactions, and electrostatic interactions were common with the active site. …”
Publicado 2019
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9885por Chesnokova, Vera, Zonis, Svetlana, Barrett, Robert, Gleeson, John, Gorbunova, Vera, Melmed, Shlomo“…In non-tumorous human colon cells treated with etoposide, GH but not IGF-1 showed enhanced DNA damage. Stable disruption of IGF-1R by lentivirus expressing shRNA in vitro, or treatment with IGF-1R inhibitor PPP in vitro and in vivo, markedly induced GH receptor expression, rendering cells more sensitive to effects of GH. …”
Publicado 2019
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9886por Ghashghavi, Mohammad, Belova, Svetlana E., Bodelier, Paul L. E., Dedysh, Svetlana N., Kox, Martine A. R., Speth, Daan R., Frenzel, Peter, Jetten, Mike S. M., Lücker, Sebastian, Lüke, Claudia“…Genome analysis of strain C50C1 showed the presence of two pmoCAB operon copies and XoxF5-type methanol dehydrogenase in addition to MxaFI. …”
Publicado 2019
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9887por Pawlukowska, Wioletta, Baumert, Bartłomiej, Gołąb-Janowska, Monika, Sobuś, Anna, Wełnicka, Agnieszka, Meller, Agnieszka, Machowska-Sempruch, Karolina, Zawiślak, Alicja, Łuczkowska, Karolina, Milczarek, Sławomir, Osękowska, Bogumiła, Paczkowska, Edyta, Rotter, Iwona, Nowacki, Przemysław, Machaliński, Bogusław“…RESULTS: Of the 32 patients who received the Lin(−) progenitor cell therapy, 6 (group I) showed improvement in articulatory functions, 23 remained stable (group II), and 3 deteriorated (group III) on the 28(th) day. …”
Publicado 2019
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9888por Le, Hai Ha Long, Bi, Xiuqiong, Ishizaki, Azumi, Van Le, Hung, Nguyen, Trung Vu, Ichimura, Hiroshi“…In the remaining five patients, HPV DNA was found at both sites, but only one showed similar strains at both sites. In the other four patients, the HPV genotypes were completely discordant between these sites. …”
Publicado 2019
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9889por Tan, Jing, Qi, Ya-Na, Zhang, Jing, Wang, Wen, Zhang, Gui-Ting, Zou, Kang, Liu, Xing-Hui, Sun, Xin“…Model 3, by adding the variable of multiple gestations to model 1, showed that IVF was not statistically associated with SMM (aOR 0.89, 95% CI 0.58 to 1.36), but multiple gestations were associated with higher risk of SMM (aOR 5.92, 95% CI 4.88 to 7.83). …”
Publicado 2019
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9890por Oya, Eriko, Durand-Dubief, Mickaël, Cohen, Adiel, Maksimov, Vladimir, Schurra, Catherine, Nakayama, Jun-ichi, Weisman, Ronit, Arcangioli, Benoit, Ekwall, Karl“…We demonstrated that cells lacking Leo1 show reduced survival in G0. In these cells, heterochromatic regions, including subtelomeres, were stabilized, and the expression of many genes, including membrane transport genes, was abrogated. …”
Publicado 2019
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9891por Wang, Ying-Hsiu, Tsai, Dong-Yan, Ko, Yi-An, Yang, Tsan-Tzu, Lin, I-Ying, Hung, Kuo-Hsuan, Lin, Kuo-I“…Surprisingly, B cell-specific Blimp-1 knockout (Cko) mice, generated by CD19 promoter driven Cre recombinase-dependent deletion of Prdm1 (gene encoding Blimp-1), showed higher frequencies of B10 cells both in the steady state and following injection with LPS, as compared with control littermates. …”
Publicado 2019
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9892por Matsunaga, Asami, Yamaguchi, Sosei, Sawada, Utako, Shiozawa, Takuma, Fujii, Chiyo“…STAR-J-P factors 1 and 2 showed significant correlations with service satisfaction (factor 1: ρ = 0.648, p < 0.001; factor 2: ρ = 0.238, p = 0.005) and medication adherence (factor 1: ρ = 0.508, p < 0.001; factor 2: ρ = 0.347, p < 0.001), but only factor 1 showed a significant relationship with empowerment (ρ = 0.283, p = 0.001). …”
Publicado 2019
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9893por Chung, Fu-Tsai, Huang, Hung-Yu, Lo, Chun-Yu, Huang, Yu-Chen, Lin, Chang-Wei, He, Chih-Chen, He, Jung-Ru, Sheng, Te-Fang, Wang, Chun-Hua“…The airways of asthma with greater yearly decline in FEV(1) showed an increased thickness of submucosa and strong expression of MMP-9. …”
Publicado 2019
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9894por Chen, Liang, Peng, Tianchen, Luo, Yongwen, Zhou, Fenfang, Wang, Gang, Qian, Kaiyu, Xiao, Yu, Wang, Xinghuan“…In addition, the Kaplan-Meier survival curve showed that patients with a lower expression of ACAT1 showed a significantly lower overall survival rate and disease-free survival rate, indicating that ACAT1 could act as a prognostic and recurrence/progression biomarker of ccRCC. …”
Publicado 2019
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9895“…Hospitals were also grouped by type of local stewardship programs (ASP): Robust (included an Infectious Diseases trained clinical pharmacist or ID physician with specific time dedicated to antibiotic review) or Non-Robust. RESULTS: Figure 1 shows before/after changes in usage at all hospitals. …”
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9896“…Results are presented narratively and in tabular format (Table 1). RESULTS: Figure 1 shows the PRISMA diagram. 19 SRs were included. …”
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9897“…Only 30% (n = 178/591) of hospitalizations had antimicrobials given for CDC confirmed infections. Figure 1 shows the most common indications for antimicrobial use. …”
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9898por Fatima. de Lima Corvino, Daniela, Gauthier, Timothy, Virginia Romero Alvarez, Maria, Madaras-Kelly, Karl, Lichtenberger, Paola“…In the most recent quarter (January–March 2019), the prescribing rate was 39%. Figure 1 shows system-wide vs. Florida region prescribing rates. …”
Publicado 2019
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9899por Sun, Yu, Chen, Cong, Xue, Ruicong, Wang, Yan, Dong, Bin, Li, Jiayong, Chen, Chen, Jiang, Jingzhou, Fan, Wendong, Liang, Zhuomin, Huang, Huiling, Fang, Rong, Dai, Gang, Yan, Youchen, Yang, Tiqun, Li, Xiangxue, Huang, Zhan-Peng, Dong, Yugang, Liu, Chen“…In contrast, compared with adenoviral-GFP injected mice, mice injected with adenoviral-Maf1 showed significantly ameliorated AB-induced cardiac hypertrophy. …”
Publicado 2019
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9900por Serra, Gregorio, Antona, Vincenzo, Corsello, Giovanni, Zara, Federico, Piro, Ettore, Falsaperla, Raffaele“…CASE PRESENTATION: We hereby describe the clinical and molecular features of two girls (aged 2 and 4 years, respectively), with non-mosaic atypical deletions. Patient 1 showed fifteen café-au-lait spots and axillary freckling, as well as a Lisch nodule in the left eye, strabismus, high-arched palate, malocclusion, severe kyphoscoliosis, bilateral calcaneovalgus foot, mild generalized hypotonia, hyperactivity and deficits of speech-related abilities. …”
Publicado 2019
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