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  1. 9941
    “…By multivariate analysis, 1(st)L ET-CDK4/6i showed a better mPFS1 and OS. Moreover, 2(nd)L ET-CDK4/6i demonstrated better mPFS2 compared to ET and CT. …”
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    First- and second-line treatment strategies for hormone-receptor (HR)-positive HER2-negative metastatic breast cancer: A real-world study
  2. 9942
    “…The results of Experiment 1 showed that D. odorifera had different RMP responses to a different N-fixing niche neighbor with root system contact. …”
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    Neighbors, Drought, and Nitrogen Application Affect the Root Morphological Plasticity of Dalbergia odorifera
  3. 9943
    “…Cognitive abilities were impaired in 18 studies (81.8%), but only 1 showed deterioration in all dimensions simultaneously. …”
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    Meningiomas and Cognitive Impairment after Treatment: A Systematic and Narrative Review
  4. 9944
    “…Apatinib combined with S-1 showed promising efficiency and was well tolerated as the second-line therapy for AGC patients. …”
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    Apatinib combined with S-1 as second-line therapy in advanced gastric cancer
  5. 9945
    “…In addition, PkJEN2‐1 can transport α‐ketoglutarate, while PkJEN2‐2 cannot. Since PkJEN2‐1 shows higher transcript abundance than PkJEN2‐2, its role in dicarboxylate transport is more important than PkJEN2‐2. …”
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    Characterization of JEN family carboxylate transporters from the acid‐tolerant yeast Pichia kudriavzevii and their applications in succinic acid production
  6. 9946
    “…RESULTS: We demonstrated that the expression of miR-458b-5p and CTNNB1 showed the opposite relationship in GCs and theca cells of hierarchical follicles. …”
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    miR-458b-5p regulates ovarian granulosa cells proliferation through Wnt/β-catenin signaling pathway by targeting catenin beta-1
  7. 9947
    “…The crystal structure of Compound 1 showed that it is six coordinated and crystallised in monoclinic, P2(1)/c space group. …”
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    Synthesis and cytotoxic activity of organotin(IV) diallyldithiocarbamate compounds as anticancer agent towards colon adenocarcinoma cells (HT-29)
  8. 9948
    “…FINDINGS: The mouse-adapted strain WBP-1 showed increased infectivity in BALB/c mice and led to severe interstitial pneumonia. …”
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    Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice
  9. 9949
    “…The presence and type of mutations did not correlate with the specific expression profiles associated with different grades. LINE-1 showed significantly lower methylation in G2/G3 versus G1 tumors (p = 0.007). …”
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    Gene Expression Profiling of Pancreas Neuroendocrine Tumors with Different Ki67-Based Grades
  10. 9950
    “…The ATTD of gross energy, dry matter, organic matter, nitrogen-free extracts, and crude ash were higher in S1 compared to S3 treatments (p ≤ 0.05), while S2 was intermediate. Pigs fed S1 showed significantly higher ATTD of phosphorus (P) compared to all other groups while ATTD of calcium was unaffected irrespective of the feeding regime. …”
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    Fermentation of Whole Grain Sorghum (Sorghum bicolor (L.) Moench) with Different Dry Matter Concentrations: Effect on the Apparent Total Tract Digestibility of Energy, Crude Nutrients and Minerals in Growing Pigs
  11. 9951
    “…After induced the EMT process in SW480 cells with TGF-β1, we found treatment of TGF-β1 showed a significant increase in cell migration along with the loss of E-cadherin and an increase in N-cadherin and Vimentin protein levels. …”
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    Calcium Channel Protein ORAI1 Mediates TGF-β Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells
  12. 9952
    por Lou, Xiaoyu, Xu, Hua
    Publicado 2021
    “…RESULTS: Two hundred patients who met the inclusion criteria were included in our study, Table 1 showed the effects of nursing intervention on measures of clinical outcomes. …”
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    The effectiveness of an emergency department nursing intervention on psychological symptoms and self-care capacities: A randomized controlled study protocol
  13. 9953
    “…Basal ECV and basal strain (2-dimensional PRS) in group 2 showed a significant negative correlation (r = −0.623, p < 0.001). Group 1 showed no regional ECV differences (basal, 37.0%; mid, 35.9%; and apical, 38.3%; p = 0.184). …”
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    Regional Amyloid Burden Differences Evaluated Using Quantitative Cardiac MRI in Patients with Cardiac Amyloidosis
  14. 9954
    “…Afucosylated human IgG1 showed stronger interaction with the murine FcγRIV, the mouse orthologue of human FcγRIIIa, indicating that this glycan change is functionally conserved between the species. …”
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    Afucosylated IgG Targets FcγRIV for Enhanced Tumor Therapy in Mice
  15. 9955
    por Tan, Sheng, Chen, Jili
    Publicado 2021
    “…Among the four cell lines evaluated, IU-TAB-1 showed the highest expression of MALAT1; thus, IU-TAB-1 cells were selected for subsequent experiments. …”
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    si-MALAT1 attenuates thymic cancer cell proliferation and promotes apoptosis via the miR-145-5p/HMGA2 pathway
  16. 9956
    “…Our reverse modeling of rhabdoid tumors with isogenic cell lines, either induced or not induced, to express SMARCB1 showed widespread differential chromatin remodeling indicative of altered BAF complex activity with ensuant histone modifications when tested by chromatin immunoprecipitation followed by sequencing (ChIP-seq). …”
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    Global Chromatin Changes Resulting from Single-Gene Inactivation—The Role of SMARCB1 in Malignant Rhabdoid Tumor
  17. 9957
    “…There was a statistical significant difference in the distribution of the REs in the ATXN1 between African and European controls (Chi-test p < 0.001), and NIPA1 showed proportionately more longer alleles (RE > 8) in Europeans vs. …”
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    Repeats expansions in ATXN2, NOP56, NIPA1 and ATXN1 are not associated with ALS in Africans
  18. 9958
    “…Expression of the major histocompatibility complex class-I (mhc1) gene, M-protein (myom2), the dopamine 2B receptor (d2br), the melatonin receptor (mtr1), and heat-shock protein beta-1 (hspb1) showed strong differential regulation and was therefore studied in 1, 8, and 15 days post-hatch (dph) larvae by RT-PCR to comprehend the roles of these genes during ontogeny. …”
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    What Goes Wrong during Early Development of Artificially Reproduced European Eel Anguilla anguilla? Clues from the Larval Transcriptome and Gene Expression Patterns
  19. 9959
    “…G1 and G2). After 28 days, G1 showed a median vascular proliferation score of 2, G2 of 2.5, and G3 of 3 (p < 0.0001, G3 vs. …”
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    Use of hypertonic glucose (10%) in the prevention of postoperative adhesions in rats
  20. 9960
    “…In patients who developed post-operative RVF requiring treatment, 32 (29.1%) showed RV dysfunction before surgery. Conclusion: In this cohort study, 2.9% of patients developed clinically significant post-operative RVF. …”
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    Post-operative Right Ventricular Failure After Cardiac Surgery: A Cohort Study
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