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9961por Zhang, Qing, Wei, Ang, Ma, Hong-Hao, Zhang, Li, Lian, Hong-Yun, Wang, Dong, Zhao, Yun-Ze, Cui, Lei, Li, Wei-Jing, Yang, Ying, Wang, Tian-You, Li, Zhi-Gang, Zhang, Rui“…Two patients with AID-associated HLH had quite different responses, with one showing reversal of the HLH abnormalities soon and the other showing no improvement, as did the two cases of unknown etiology. …”
Publicado 2020
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9962por Silva, Vanessa, Vieira-Pinto, Madalena, Saraiva, Cândido, Manageiro, Vera, Reis, Lígia, Ferreira, Eugénia, Caniça, Manuela, Capelo, José L., Igrejas, Gilberto, Poeta, Patrícia“…All strains, except one, showed resistance to tetracycline and harbored the tetM, tetK and tetL genes in different combinations. …”
Publicado 2021
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9963“…Comprehensive statistical analyses show how genomics and epigenomics affect the expression of examined genes differently across various pathohistological types and grades, suggesting that genes AKT3, CHUK and PTEN behave like tumor suppressors, while AKT1, AKT2, EGFR, and PIK3AP1 show oncogenic behavior and are involved in enhanced activity of the EGFR-PI3K-AKT-mTOR signaling pathway. …”
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9964por Saw, Khay Yong, Ng, Reza, Jee, Caroline, Low, Soo Fin, Dorvault, Christopher, Johnson, Kevin, Anz, Adam“…All other KOOS subdomains, NRS and MOCART scores were statistically significant (P < 0.0001) at month-24. Figure 1 shows the bar graphs of the co-primary endpoints. …”
Publicado 2021
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9965“…In addition, animals treated with Q-1 showed lower inflammation in the ankle joints than the model rats. …”
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9966“…All isolates were found As tolerant, of which one isolate, Pseudomonas sp. QNC1, showed the highest tolerance up to 350-mM concentration in the LB medium. …”
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9967por de Santa-Inez, Daniel Casartelli, Fuziwara, Cesar Seigi, Saito, Kelly Cristina, Kimura, Edna Teruko“…As a result, we observed that the ATC cell line KTC2-Cl1 showed a 60% decrease in the expression of miR-146b-5p compared to the control, also showing reduced cell viability, migration, colony formation, and blockage of tumor development in immunocompromised mice. …”
Publicado 2021
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9968por Dankner, Matthew, Maritan, Sarah, Zhuang, Rebecca, Caron, Maxime, Priego, Neibla, Valiente, Manuel, Petrecca, Kevin, Siegel, Peter“…Cancer cells treated with recombinant Chi3L1 showed greater invasion into brain slice cultures compared to untreated cells. …”
Publicado 2021
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9969por Asaad, Gihan Farag, Ibrahim Abdallah, Heba Mohammed, Mohammed, Hala Shaaban, Nomier, Yousra Ahmed“…They also exerted a powerful antioxidant effect by modulating the oxidative stress induced by paracetamol via increasing GSH, reducing MDA and nitrotyrosine concentrations compared to positive control. The glycoside (1) showed a better effect than silymarin (standard) in ameliorating the formation of nitrotyrosine, Raf-1 kinase, c-JNK, and GSH. …”
Publicado 2021
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9970por Sargiacomo, Camillo, Stonehouse, Sophie, Moftakhar, Zahra, Sotgia, Federica, Lisanti, Michael P.“…Functionally, the Mito-high cell population was specifically enriched in cancer stem cell (CSC) activity, i) showing increased levels of ESA cell surface expression and ALDH activity, ii) elevated 3D anchorage-independent growth, iii) larger overall cell size (>12-μm) and iv) Paclitaxel-resistance. …”
Publicado 2021
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9971por Feng, Fan, Zhao, Zongqing, Zhou, Yunfei, Cheng, Yanhao, Wu, Xiujie, Heng, Xueyuan“…In comparison with untreated cells, TJ905 glioma cells overexpressing CUX1 showed higher proliferation and invasion abilities and S phase cell-cycle arrest, while the knockdown of CUX1 suppressed cell invasive ability and induced G1 phase arrest. …”
Publicado 2021
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9972“…The optimization of physicochemical parameters and analysis of the free amino acid constituents of the feather hydrolysate were also carried out. FANN1 showed a maximum keratinase yield of 1,664.55 ± 42.43 U/mL after 72 h, at optimal process conditions that included initial medium pH, incubation temperature, inoculum size, and chicken feather concentration of 8, 30°C, 4% (v/v), and 15 (g/L), respectively. …”
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9973“…However, Group-II comparison with Group-I showed that weaning from CPB was superior in-Group-II with p-value of 0.016. …”
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9974“…Functional experiments demonstrated that silencing FoxD2-AS1 inhibited proliferation and induced cell arrest at G(0)/G(1) phase in CRC cells, while the overexpression of FoxD2-AS1 showed opposite results. Ki-67 and proliferating cell nuclear antigen expression levels were decreased after transfection with small interfering RNA FoxD2-AS1, but were increased after transfection with FoxD2-AS1 overexpression plasmid. …”
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9975por Veeratterapillay, Rajan, Gravestock, Paul, Nambiar, Arjun, Gupta, Ameet, Aboumarzouk, Omar, Rai, Bhavan, Vale, Luke, Heer, Rakesh“…Two studies reported recurrence data at 60 mo showing statistically significant outcomes in favour of PDD: one showed lower RRs for PDD (49% PDD vs 68% WL), whilst the other showed increased recurrence-free survival (68.2% PDD vs 57.3% WL). …”
Publicado 2021
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9976por Van Liefferinge, Elout, Müller, Maximiliano, Van Noten, Noémie, Degroote, Jeroen, Niknafs, Shahram, Roura, Eugeni, Michiels, Joris“…Results showed a significant effect of capsaicin on GLP-1 release in the proximal small intestine, TRPV1 independent. TRPA1 showed to be strongly activated by cinnamaldehyde, both in proximal and distal small intestine, evidenced by the release of CCK and GLP-1, respectively. …”
Publicado 2021
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9977“…In this work we present a reduced visual system model (RVSM) of the first level of scene analysis, involving the retina, the lateral geniculate nucleus and the primary visual cortex (V1), showing orientation selectivity. The detection core of the RVSM is the neuromorphic spike-decoding structure MNSD, which is able to learn and recognize parallel spike sequences and considerably resembles the neuronal microcircuits of V1 in both topology and operation. …”
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9978por Jang, Jong Keon, Lee, Chul-min, Park, Seong Ho, Kim, Jong Hoon, Kim, Jihun, Lim, Seok-Byung, Yu, Chang Sik, Kim, Jin Cheon“…Algorithms for combining T2WI and DWI were as follows: ‘AND,’ if both showed CR; ‘OR,’ if any one showed CR; and ‘conditional OR,’ if T2WI showed CR or DWI showed CR after the pre-treatment DWI showed homogeneous hyperintensity. …”
Publicado 2021
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9979por Brittain, Kirsty, Teasdale, Chloe A, Ngeno, Bernadette, Odondi, Judith, Ochanda, Boniface, Brown, Karryn, Langat, Agnes, Modi, Surbhi, Abrams, Elaine J“…RESULTS AND DISCUSSION: Of 37 papers examining approaches to increase retention among pregnant and postpartum WLHIV, only two reported age‐disaggregated results: one showed that integrated care during the postpartum period increased retention in HIV care among women aged 18 to 24 years; and another showed that a lay counsellor‐led combination intervention did not reduce attrition among women aged 16 to 24 years; one further study noted that age did not modify the effectiveness of a combination intervention. …”
Publicado 2021
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9980por Chen, Xinyue, Liu, Yifei, Jin, Junhua, Liu, Hui, Hao, Yanling, Zhang, Hongxing, Xie, Yuanhong“…Plantaricin BM-1, a class IIa bacteriocin produced by Lactobacillus plantarum BM-1, shows obvious antibacterial activity against Escherichia coli. …”
Publicado 2021
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