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10701“…RESULTS: 1,253 unique patients were screened for inclusion. 772 were hypoxic at baseline, leaving 481 patients for analyses: 67 patients (14%) received ≥ 5 days and 406 (86%) received ≤ 4 days. Table 1 shows demographic data and baseline characteristics. …”
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10702por Taketani, Makoto, Inagaki, Tsubasa, Nakada, Mitsutaka, Ariizumi, Reiichi, Nakajima, Masakazu, Fujisawa, Akihiko, Tezen, Tomoya, Tsunashima, Takanori, Ito, Kaoru, Abe, Daichi, Yamaguchi, Kazunori, Ohnuma, Kenichiro, Ishida, Nami, Ebisawa, Kei Furui, Ohji, Goh“…Application for inhibition circle measurement was also conducted using Escherichia coli with two antibiotic discs (amoxicillin/clavulanic acid and ampicillin/sulbactam). RESULTS: Figure 1 shows the OD measured at the pixels in the high concentration area (blue) and single colony area (red) superimposed on the transmitted light image of the last frame. …”
Publicado 2023
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10703por Hooton, Thomas M, Perry, Caroline R, Janmohamed, Salim, Sheets, Amanda, Dennison, Jeremy, Millns, Helen, Jarvis, Emily, Scangarella-Oman, Nicole E, Huang, Chun“…RESULTS: The pooled micro-ITT population comprised 1421 patients (732 gepotidacin, 689 nitrofurantoin). Table 1 shows E. coli drug-resistant phenotypes at baseline. …”
Publicado 2023
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10704“…The genes WASL, ENPP5, ARL6IP1, and IDH1 showed the most significant and strongest downregulation after hsa-miR-142-3p, -17-5p, -223-3p, and -30e-5p transfection, respectively. …”
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10705“…After 30 days of MA, 31% of patients treated with MA at 160 mg day-1 showed an increase in body weight, 25% a stabilisation and 44% a decrease. …”
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10706por Sheahan, Sharon, Bellamy, Christopher O, Dunbar, Donald R, Harrison, David J, Prost, Sandrine“…Hepatocytes deficient in p53 or p21(Cip1 )showed diminished growth inhibition by TGFβ. Double deficiency had a similar impact showing that in cells containing functional pRb; P21(Cip )and P53 work through the same pathway to regulate G1/S in response to TGFβ. …”
Publicado 2007
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10707por Yang, Zhenjiang, Xu, Haoxing, Cui, Ningren, Qu, Zhiqiang, Chanchevalap, Sengthong, Shen, Wangzhen, Jiang, Chun“…In the presence of 10 μM PIP(2), the Kir4.1–Kir5.1 showed a pKa value of 7.22. The effect of PIP(2), however, was not seen in homomeric Kir4.1 currents. …”
Publicado 2000
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10708por Kanibolotsky, Dmitry S, Novosyl'na, Oleksandra V, Abbott, Catherine M, Negrutskii, Boris S, El'skaya, Anna V“…RESULTS: It has been determined by multiple MD simulation that eEF1A1 shows increased reciprocal flexibility of structural domains I and II and less average distance between the domains, while increased non-correlated diffusive atom motions within protein domains characterize eEF1A2. …”
Publicado 2008
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10709por Kolanczyk, Mateusz, Kühnisch, Jirko, Kossler, Nadine, Osswald, Monika, Stumpp, Sabine, Thurisch, Boris, Kornak, Uwe, Mundlos, Stefan“…Mice with conditionally inactivated neurofibromin (Nf1) in the developing limbs and cranium (Nf1Prx1) show bowing of the tibia caused by decreased bone mineralisation and increased bone vascularisation. …”
Publicado 2008
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10710“…This was not seen for Snail2, and Zeb1/δEF1 showed a reverse correlation with lower expression values being predictive of increased risk. …”
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10711“…When R-3-hydroxyoctanoic acid was used as substrate, the granule-bound PhaC1 exhibited a Km of 125 (± 35) μM and a Vmax of 40.8 (± 6.2) U/mg PhaC1, while a Km of 37 (± 10) μM and a Vmax of 2.7 (± 0.7) U/mg PhaC2 could be derived for the granule-bound PhaC2. Granule-bound PhaC1 showed a strong preference for medium chain length (mcl-) 3-hydroxyacly-CoAs, with highest affinity towards 3-hydroxydecanoyl-CoA (40 U/mg PhaC1). …”
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10712por Muggerud, Aslaug Aa, Rønneberg, Jo Anders, Wärnberg, Fredrik, Botling, Johan, Busato, Florence, Jovanovic, Jovana, Solvang, Hiroko, Bukholm, Ida, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Sørlie, Therese, Tost, Jörg“…CONCLUSIONS: Quantitative methylation analysis identified ABCB1, FOXC1, PPP2R2B and PTEN as novel genes to be methylated in DCIS. In particular, FOXC1 showed a significant increase in the methylation frequency in invasive tumours. …”
Publicado 2010
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10713por Mukherjee, Asama, Dutta, Sushanta, Shanmugavel, Muthiah, Mondhe, Dilip M, Sharma, Parduman R, Singh, Shashank K, Saxena, Ajit K, Sanyal, Utpal“…CONCLUSIONS: In essence, compound 1i showed potential as an antitumor agent.…”
Publicado 2010
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10714por Scoles, Haley A, Urraca, Nora, Chadwick, Samuel W, Reiter, Lawrence T, LaSalle, Janine M“…Previous analysis of two postmortem dup15q frontal cortical samples showed heterogeneity between the two cases, with one showing levels of the GABA(A )receptor genes, UBE3A and SNRPN in a manner not predicted by copy number or parental imprint. …”
Publicado 2011
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10715por Kaku, Yoshihiro, Noguchi, Akira, Okutani, Akiko, Inoue, Satoshi, Tanabayashi, Kiyoshi, Yamamoto, Yoshie, Hotta, Akitoyo, Suzuki, Michio, Sugiura, Naoko, Yamada, Akio“…DISCUSSION: Using a phage display library, we obtained 7 soluble scFv clones reactive against H1N1pdm; however, only 1 showed specificity/preference toward H1N1pdm. Our results confirmed that using phage display libraries was highly advantageous for the rapid development of molecules to detect target antigens. …”
Publicado 2012
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10716“…In August, meanwhile, HTIR 1 showed the highest as 0.075, and followed by HTIR 3, Chungpoong, and HTIR 2 with 0.070, 0.047, and 0.023, respectively. …”
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10717“…These weights preferentially reassign untested cases located in regions of reduced testing, reflecting an assumption that in areas where testing is common, individuals most at risk are tested. Fig. 1 shows two risk maps created by this weighted DBM, one on the unadjusted data (Fig.1, L) and one using the informative weights (Fig. 1, R). …”
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10718“…Two types of cores were identified based on type of neighborhood - Contiguous (CC) & within a defined Radius (CR). Table 1 shows the analysis of counties according to valid frequency criteria for both CC & CR (r=2) & their sub-classification. …”
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10719por Adams, Arthur, van Brussel, Aram SA, Vermeulen, Jeroen F, Mali, Willem PThM, van der Wall, Elsken, van Diest, Paul J, Elias, Sjoerd G“…Expression rates increased with tumor grade for GLUT1, CAIX, and CXCR4 (all p < 0.001), but decreased for IGF1R (p < 0.001). GLUT1 showed the highest expression rate in grade III cancers with 58% (45-69%). …”
Publicado 2013
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10720por Paranjape, Anurag N, Balaji, Sai A, Mandal, Tamoghna, Krushik, Esthelin Vittal, Nagaraj, Pradeep, Mukherjee, Geetashree, Rangarajan, Annapoorni“…Bmi1-high tumors showed elevated Nanog expression whereas the tumors with lower Bmi1 showed reduced Nanog levels. Overexpression of Bmi1 increased Nanog levels whereas knockdown of Bmi1 reduced its expression. …”
Publicado 2014
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