“…In addition, Caerin1.1 showed powerful antiviral activity without interfering with the binding progress between PEDV and the receptor of the cells, therefore, it could be used as a potential antiviral drug or as a microbicide compound for prevention and control of PEDV.…”
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“…The results have been published in doi:10.1016/j.exer.2018.06.024 (Cui et al., 2018) [1]. Fig. 1 shows the expression quantitative trait loci (eQTL) that regulate the expression level of each gene in the Vegf family. …”
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“…The effects observed on the shoot were similar for both molecules, but while compound 1 showed a stronger effect on root parameters (such as primary root length, root hair and density, showing lower ED(50) values), compound 2 caused important malformations in root morphology. …”
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“…The leishmanicidal activity of compounds 1–9 against Leishmania amazonensis was tested on promastigote forms and cytotoxicity against J774 (macrophage cell line) was assessed in vitro. Compound 1 showed potent activity (IC(50) = 0.18 µg/mL), compared with the standard amphotericin B (IC(50) = 0.20 µg/mL). …”
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“…This trial reported that corticosteroids increased the proportion of patients with complete resolution of pain at 48 hours. Box 1 shows all of the articles and evidence linked in this Rapid Recommendation package. …”
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“…After two doses, we performed reirradiation with HSRT. Case 1 showed regression at both the local and the metastatic sites after radiotherapy. …”
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“…In the U251MG GBM xenograft models, MCCK1 showed synergistic therapeutic effects in combination with TMZ to reduce tumor volumes significantly. …”
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“…In this work, we performed a computational approach that identifies tissue-specific co-expression networks by integrating miRNAs, long-non-coding RNAs, and mRNAs in more than eight thousands of human samples from thirty normal tissue types. Our analysis (1) shows that long-non coding RNAs and miRNAs have a high specificity, (2) confirms several known tissue-specific RNAs, and (3) identifies new tissue-specific co-expressed RNAs that are currently still not described in the literature. …”
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“…Notably, a key marker of cardiovascular disease PAI-1 showed a difference in concentration between the obese and lean groups only in plasma. …”
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“…In contrast to kinesin-1 showing normally single-exponential distribution of run lengths, dimerized kinesin-3 shows puzzlingly Gaussian distribution of run lengths. …”
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“…In addition, we tested whether the gender of a face and the gender of a participant can influence the preconscious processing of facial trustworthiness and dominance. Experiment 1 showed that the least and most trustworthy faces both took significantly less time to break into awareness than neutral faces. …”
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“…The immunosensor for cardiac troponin I shows a linear range from 0.05 to 20 ng mL(–1) with a detection limit of 0.04 ng mL(–1) (S/N = 3).…”
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“…We recently encountered two AFS cases with differing postoperative courses. Case 1 showed evident exacerbation in the computed tomography findings, which suggests progression to eosinophilic sinusitis. …”
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“…I use data from a UK national stratified survey to test the hypothesis that eating with others provides both social and individual benefits. I show that those who eat socially more often feel happier and are more satisfied with life, are more trusting of others, are more engaged with their local communities, and have more friends they can depend on for support. …”
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“…In particular, we found that JQ1 shows additional activity with venetoclax, in CLL cell lines and in ex vivo isolated primary CD19(+) lymphocytes, arguing in favour of combination strategies. …”
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“…In the present study, our goal was to investigate whether stories portraying a strong protagonist can positively influence recipients’ beliefs of being in control of events in their own lives (self-related control beliefs). Experiment 1 showed that narratives in both written text and video form with protagonists displaying high versus low self-efficacy can, at least temporarily, affect recipients’ own self-related control beliefs when they experience strong transportation into the stories. …”
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“…The optimal compound 7i showed superior anticancer activity against the HepG-2 cell line with an IC(50) value of 26.39 μM.…”
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“…By focussing on a life-threatening environmental phenomenon I show that the consideration of the individual’s age-specific hazard rate is important. …”
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“…Through detailed analysis of a wide variety of clinical examples, including Alzheimer disease as a test case, I show how nosology, research, and decisions about diagnostic criteria should include normative as well as naturalistically describable factors.…”
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“…In addition to thermal constraints, proposed failure mechanisms for deep earthquakes all require that sufficient strain accumulates in the slab at a relatively high stress. Here, I show that simulations of subduction with nonlinear rheology and compositionally dependent phase transitions exhibit strongly variable strain rates in space and time, which is similar to observed seismicity. …”
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