“…Proton nuclear magnetic resonance-based serum metabolic study was implemented on rat sera to explore the effects of M1 on hepatocellular carcinoma-induced metabolic alterations. RESULTS: M1 showed protective action on liver and restored the arrangement of liver tissues in normal proportion. …”
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“…The supplementation of HIPS1 and HIPS2 significantly decreased the blood glucose (GLU) levels; suppressed the abnormal elevations of alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea nitrogen (BUN) and creatinine (CRE) levels in serum; improved the antioxidant enzymatic (superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT)) activities; and attenuated the pathological damage to these organs. The HIPS1 showed superior effects in antihyperglycaemia and organic protection than HIPS2 possible owing to the abundant functional groups (-NH(2), -COOH and S=O) in HIPS1, indicating that H. erinaceus SG-02 could be used as a functional food and natural drug for the prevention of diabetes and its complications.…”
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“…RESULTS: All patients except one showed statistically significant improvements in activities of daily living (ADL) and motor symptoms, as measured by flexion angle at standing posture, Unified Parkinson's Disease Rating Scale (UPDRS) II and III, and modified Hoehn-Yahr staging. …”
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“…[Results] In the comparison of balance ability and gait ability between the groups for before and after intervention, Group I showed a significant difference in balance ability and gait ability compared to Groups II and III. …”
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“…Importantly, this study, in tandem with other recent ones, shows that this rare genetic form of aplastic anemia is treatable with THPO receptor agonists, emphasizing the paramount role of genetic testing in cases of aplastic anemia and other bone marrow failure disorders. …”
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“…The highly selective imprinted polymer for gallic acid was MIPI1 with a composition (molar ratio) of 1:4:20, template: monomer: cross-linker, respectively. The MIPI1 showed highest binding efficiency (79.50%) as compared to other imprinted and non-imprinted polymers. …”
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“…Therefore, by this education seminar, I lecture mainly on the EVHA, SEPS and foam sclerotherapy in varicose vein treatment. Finally I show one case which you should remember. (This is a translation of Jpn J Vasc Surg 2017; 26: 225–230.)…”
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“…CASE REPORT: In this case study, we report two cases of CHAOS with one showing laryngeal atresia and the other, tracheal atresia. …”
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“…Accordingly, mice lacking LRIT1 show visual deficits under conditions requiring temporally challenging discrimination of visual signals in steady background light. …”
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“…Among them, compound 5c-1 showed the most potent activity on inhibiting HBsAg secretion (IC(50) = 39.93 μM, SI = 28.51). …”
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“…The antioxidant activities of the fractions and isolates were evaluated using different in vitro methods, such as DPPH, superoxide anion and nitric oxide radicals scavenging assays. Compound (1) showed a promising antioxidant activity with IC(50) 0.1, 0.08, and 0.09 µM in the three assays, respectively, comparable to ascorbic acid.…”
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“…Here, I study such coevolution with a simple yet realistic model of within-group social structure where social connections are either inherited from a parent or made randomly. I show that cooperation evolves when individuals make few random connections, but the presence of cooperation selects for increased rates of random connections, which leads to its collapse. …”
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“…By live-cell imaging of individual endosomes in human cells, we find that ESCRT proteins are recruited in a repetitive pattern: ESCRT-0 and -I show a gradual and linear recruitment and dissociation, whereas ESCRT-III and its regulatory ATPase VPS4 display fast and transient dynamics. …”
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“…Using three measures (cortisol, heart-rate and mood questionnaire) I show that subjects in the treatment group were under considerable levels of stress. …”
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“…The resistant isolates with mutations in hmg1 showed increased intracellular ergosterol levels compared with susceptible isolates. …”
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“…Their structures were elucidated by extensive spectroscopic analysis and comparison with the literature. Compound 1 showed remarkable inhibitory activity towards NO production in LPS-stimulated RAW264.7 cells (IC(50) = 1.8 μM) and weak cytotoxicity towards five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, SW480).…”
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“…Here using a meta-community model of a food web, I show that compartments have less effect on community stability than previously thought. …”
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“….% binary mixture of ZIF-8 and ZIF-67 yielded a proton conductivity of 9.2 × 10(−2) S·cm(−1), showing a synergistic effect on the proton conductivity.…”
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“…Compound 7, with low toxicity to zebrafish (LC(50) = 378.387 µg mL(−1)) showed 100% inhibition against mosquito (Culex pipiens pallens) at 0.25 µg mL(−1). …”
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“…The crystal structure of complex I shows that the molecular is a dimer, in which two [(5-Fu)-1-CH(2)CH(2)COOSn(n-Bu)(2)](2)O units are linked by a bridging oxygen atom, and the tin atoms adopt distorted trigonal bipyramids via two carbons from a dibutyl moiety and three oxygen atoms from 5-Fu and bridging oxygen. …”
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