“…JAG1 expression increases while DLL4 expression decreases. Jagged1 shows a unique response by clustering intracellularly six to nine hours after the onset of flow. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among them, compounds 5d, 5e, 5f, and 5i showed prominent activity against B. cinerea, with determined EC(50) values of 5.21 μg/mL, 8.25 µg/mL, 8.03 µg/mL, and 21.00 µg/mL, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The compounds 3d, 3e, 3f and 3i showed good ferric and cupric reducing abilities, and the compounds 3b and 3c showed the weakest reducing power in the series.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…From the 153 mentioned compounds, only 27 passed were tested for biological activity, being usnic acid the most studied compound and the one showing the best results in almost all in vitro tests performed, although other compounds also presented excellent results as antimicrobial, antitumor and anti-inflammatory agents, among others. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Its structure was elucidated by spectroscopic analyses including NMR and HR-MS. Haliamide (1) showed cytotoxicity against HeLa-S3 cells with IC(50) of 12 μM. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results demonstrated that several proteins, including eukaryotic translation elongation factor 2 (eEF2) and enolase I, showed a differential expression pattern during the neuronal cell death process, and this was MAPK pathway dependent. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Consequently, the number and variety of products chosen tends to increase when they are arranged horizontally. I show that this horizontal display advantage can be modulated by culture, especially writing and reading habits. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Hemodynamic ischemia of the AChA territory is rare, however, should be considered as a potential target of treatment when the ipsilateral ICA, A1 and M1 show stenoocclusive lesions.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Anti-onchocercal screening of 1 showed moderate inhibition of adult worm motility of Onchocerca ochengi by 60% at the highest concentration (20 µg/mL) and inhibited motility of both the juvenile worms of O. ochengi and Loa loa by 90% at this same concentration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, Dpp4 and Xnr1 showed synergistic effect on induction of ectopic dorsal body axis, when co-injected at suboptimal doses in early embryos. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The current study investigated whether Chinese character reading requires the interaction between orthography-to-phonology consistency and semantic processing of the whole character (imageability, Experiment 1) or the semantic radical (transparency, Experiment 2). Experiment 1 showed a significant effect of the consistency and a marginal effect of the imageability, but no interaction between the two. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we measure pH(ECM) in the growing edge of Stylophora pistillata by simultaneously using microsensors and the fluorescent dye SNARF-1, showing that, when measured at the same time and place, the results agree. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In Rhodobacter capsulatus, gene rcc01865 encodes a putative regulatory protein that is essential for GTA production. Here, I show that rcc01865 (hereafter gafA) encodes a transcriptional regulator that binds to the GTA promoter to initiate production of structural and DNA packaging components. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Shifts in fringe visibility of the interference pattern are monitored and tested against the common sense null hypothesis that such shifts should not correlate with the participant’s attention state. We i/ show that the original statistical test used in [1] contains an erroneous trimming procedure leading to uncontrolled false positives and underestimated p-values, ii/ propose a deeper analysis of the dataset, identifying several preprocessing parameters and carefully assessing the results’ robustness regarding the choice of these parameters. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In both experiments, we use an adaptation of the retrieval practice paradigm [1] to modulate memory accessibility of potential solutions to a subsequent set of analogy problems of the type ‘A is to B as C is to ?’. Experiment 1 showed a retrieval-induced impairment in analogical problem solving. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There are several rules-of-thumb but, surprisingly (given that the problem is so common in science), none seem to be evidence-based. RESULTS: Here I show how the significance of a digit in a particular decade of a mean depends on the standard error of the mean (SEM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We considered two possible explanations for fistula formation: radiation enterocolitis after CIRT might cause formation of the fistula long-term, and tumor regrowth might compress the rectum and cause fistula formation. A biopsy in Case 1 showed that regrowth tumor was post-CIRT. It is important to be aware of the possibility of rectal complications after CIRT, and if found, resection of the rectum should be considered. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we uncovered a noncanonical function of U2AF1, showing that it directly binds mature mRNA in the cytoplasm and negatively regulates mRNA translation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Drawing on quantitative analyses of dental evolutionary rates and Bayesian analyses of hominin phylogenetic relationships, I show that any divergence time between Neanderthals and modern humans younger than 800 ka ago would have entailed unexpectedly rapid dental evolution in early Neanderthals from Sima de los Huesos. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…NMR-assisted binding studies and steady-state kinetics studies performed on aza-stilbene derivative 1 showed, surprisingly, that it acts as a competitive inhibitor of MurD activity towards D-glutamic acid, and additionally, that its binding to the D-glutamic acid binding site is independent of the enzyme closure promoted by ATP.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso