“…Primary result is blood pressure, while secondary results are treatment compliance, waist circumference, body mass index (BMI), type and number of antihypertensive agents used, and the existence of metabolic and cardiovascular comorbidities. RESULTS: Table 1 shows the clinical outcomes between the two groups. …”
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“…By contrast, glycosylase Neil1 showed more activity on the G4 than the duplex conformation. …”
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“…Most theories of crack propagation focus on the near crack tip region. Remarkable, here I show that a simple theory which does not account for the nature of the stress field in the near crack tip region results in a crack propagation energy in semiquantitative agreement with a theory based on the stress field in the near crack tip region. …”
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“…An Alzheimer’s mouse model containing phospho-deficient PS1 show severe Aβ accumulation in microglia as well as the postsynaptic protein PSD95. …”
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“…All the compounds (1–5) were tested for their in vitro cytotoxic and anti-neuroinflammatory activities. Among them, 1 showed moderate cytotoxic activity against a panel of cancer cell lines (HCT-15, NUGC-3, NCI-H23, ACHN, PC-3, and MDA-MB-231) with GI(50) values ranging from 44.4 to 91.6 μM, whereas compounds 2 and 5 exhibited anti-neuroinflammatory effect without cytotoxicity against all the tested cell lines.…”
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“…Using 3 months of location data, we (1) show the risk of re-identification to decrease slowly with dataset size, (2) approximate this decrease with a simple model taking into account three population-wide marginal distributions, and (3) prove that unicity is convex and obtain a linear lower bound. …”
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“…Previously (Nee and D’Esposito, 2016; 2017), we detailed frontal dynamics that support control processing, but left open their role in broader cortical function. Here, I show that the FPCN consists of an external/present-oriented to internal/future-oriented cortical gradient extending outwardly from sensory-motor cortices. …”
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“…Here we produced, purified, and biochemically characterized recombinant PfPanK1 for the first time. PfPanK1 showed activity using pantetheine besides pantothenate, as the primary substrate, indicating that CoA biosynthesis in the blood stage of P. falciparum can bypass pantothenate. …”
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“…Polyethylenimine (PEI) was added to increase the aspect ratio of ZNRs, which reached up to 24:1, showing the best energy harvesting performance of NGs. …”
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“…In the cortical somatosensory network, neurons of the primary somatosensory cortex (S1) show invariant sensory responses, while frontal lobe neuronal activity correlates with the animal’s perceptual behavior. …”
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“…Using a composite FE model dataset, I show that the combination of small taxonomic sample sizes and comparative FE data in analyses of evolutionary associations of biomechanical performance to feeding ecology generates artificially elevated correlations. …”
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“…PPARγ-ligand-incorporated 7-methoxycoumarin, 1, showed weak fluorescence intensity in a previous report. …”
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“…Of the three included studies, two of them had a moderate risk of bias and one showed a high risk of bias. CONCLUSION: The use of rotary instruments contributed to a lower incidence and intensity of postoperative pain than did the hand instruments in all the three studies. …”
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“…Both novels focus on characters whose development as human beings is prevented by the contrasting illusions of ephemerality and digital hypermnesia. I show that the way characters use social media entails a sense of virtual disembodiment that shapes their perception of their physical bodies and surrounding spaces. …”
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“…Among three paralogs of plant PARPs, PARP1 showed a close association with growth rate. PARPs catalyze poly(ADP-ribosyl)ation and play pivotal roles in DNA repair and antipathogen defense. …”
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“…The serum levels of cytokines were measured on days 0, 15, and 30. Group 1 showed an increased serum level of IL-1β, IL-6, and TNF-α after 15 days, and they decreased in day 30. …”
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“…MCS may be becoming weaker and less frequent. I show that MHW/MCS in the Tasman Sea co-occur with corresponding events in the Atlantic, Indian, and eastern-Pacific Oceans, and these southern hemisphere events are likely driven by stalling of a global wavenumber-4 (W4) atmospheric wave, leading to anomalously weak north-easterly winds during MHW or strong south-westerly winds during MCS. …”
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“…Specifically, Study 1 examined the moderating effect of the pandemic on the relationship between six predictors (perceived usefulness, perceived ease of use, price saving benefit, time saving benefit, food safety risk perception, and trust) and OFD usage intention, and Study 2 extended the model by adding customer perceptions of COVID-19 (perceived severity and vulnerability) during the pandemic. Study 1 showed that all of the predictors except food safety risk perception significantly affected OFD usage intention, but no moderation effect of COVID-19 was found. …”
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“…The antiproliferative effect of Fe1 was even higher than cisplatin. Interestingly, Fe1 showed low in vivo toxicity, and in vivo analyses of Fe1 and Fe2 compounds using colorectal HCT116 zebrafish xenograft showed that both reduce the proliferation of human HCT116 colorectal cancer cells in vivo.…”
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“…Compounds 1, 2, and 3 were found to bind with equal affinity to both targets. Compound 1 showed the highest predictive docking scores, and was further subjected to molecular dynamics (MD) simulation to explain protein stability, ligand properties, and protein–ligand interactions. …”
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