“…The neglect of Chagas disease is further illustrated by the lack of a robust and diverse drug discovery and development portfolio of new chemical entities, and it is of paramount importance to build a strong research and development network for antichagasic drugs. …”
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“…[Image: see text] Spectroscopy simulations are of paramount importance for the interpretation of experimental electronic spectra, the disentangling of overlapping spectral features, and the tracing of the microscopic origin of the observed signals. …”
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“…With rising numbers of TAVR being performed, the focus on prevention and successful management of vascular complications will be of paramount importance to lower morbidity and mortality of the procedures. …”
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“…Insightful knowledge on quantum nanostructured materials is paramount to engineer and exploit their vast gamut of applications. …”
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“…Direct chemical vapor deposition (CVD) growth of wafer-scale high-quality graphene on dielectrics is of paramount importance for versatile applications. Nevertheless, the synthesized graphene is typically a polycrystalline film with high density of uncontrolled defects, resulting in a low carrier mobility and high sheet resistance. …”
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“…The findings demonstrate the potential of psychotherapy to contribute to normalizing perceptual, cognitive, and relational capacities in severely traumatized refugees, paramount to well-being and functioning in exile.…”
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“…On the other hand, the use of these materials in powder form is not workable, the development of scalable and economical processes and integrative of these materials onto beads is paramount for industrial processes. Hence, it was reported a scalable, bio aqueous solution-based preparation strategy for Bio Zr-MOF beads production. …”
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“…These surface interactions are of paramount importance and have been therapeutically exploited for antiviral design, such as monoclonal antibodies. …”
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“…The coronavirus has become the paramount subject in peoples’ lives, affecting and disrupting virtually every aspect of society, as the pandemic casts a shadow over the world. …”
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“…G-protein coupled receptors (GPCRs) play a paramount role in diverse brain functions. Almost 20 years ago, GPCR activity was shown to be regulated by membrane potential in vitro, but whether the voltage dependence of GPCRs contributes to neuronal coding and behavioral output under physiological conditions in vivo has never been demonstrated. …”
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“…To prevent these negative outcomes, knowledge of existing transitional care interventions is paramount. Therefore, a scoping review was performed, summarizing current interventions aiming to improve transitional care. …”
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“…Free radicals play a role of paramount importance in the development of neonatal brain injury. …”
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“…Understanding this role is of paramount importance because in-depth knowledge of the connection between macrophages and this systemic disease could clarify its pathogenesis and provide a foundation for macrophage-centered therapeutic approaches.…”
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“…Today, accurate and automated abnormality diagnosis and identification have become of paramount importance as they are involved in many critical and life-saving scenarios. …”
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“…With the rising trend of consumers being offered by start-up companies portable devices and applications for checking quality of purchased products, it appears of paramount importance to assess the reliability of miniaturized sensors embedded in such devices. …”
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“…The proof of the reliability of a numerical model is becoming of paramount importance in the era of in silico trials. …”
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“…Therefore, the studies of the electronic correlation effects in the new 2D materials is of paramount importance for the understanding of their transport, optical and catalytic properties. …”
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“…Prompt recognition and treatment is paramount. Kusko RE, Singhal E, Kauffman RP. Clitoral Priapism in a Transgender Male. …”
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“…In order to better understand how current therapeutics and those under development target DV processes, techniques used to investigate the DV are paramount. This review outlines the involvement of the DV in therapeutics currently in use and focuses on the range of techniques that are currently utilized to study this organelle including microscopy, biochemical analysis, genetic approaches and metabolomic studies. …”
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“…The results of this study show that highly absorbent porous materials are the most sensitive to viscous and thermal surfaces, which makes the consideration of these two parameters paramount for the characterization of highly absorbent porous materials using the waves reflected from the first interface.…”
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