“…That said, the need for proper authentication and authorization is paramount. Access control is in the front line of such mechanisms. …”
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“…In vitro and in vivo models have been developed, supporting the role of PINK1 in synaptic transmission, particularly affecting dopaminergic neurons. It is of paramount importance to further define the role of PINK1 in mitophagy and mitochondrial homeostasis in PD pathogenesis in order to delineate novel therapeutic targets.…”
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“…Sustainable management is a key factor in improving wood quality. It is of paramount importance to understand the molecular and genetic mechanisms underlying wood formation, together with the hormonal and environmental factors that affect wood formation and quality. …”
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“…The roles of specific hemodynamic variables, the non-Newtonian behavior of blood and its particulate nature at small scales, the flow disturbances caused by the heart cycle, and the anatomy of certain arteries (i.e., bifurcations and tortuosity of vessels of some regions) in the determination of the dynamic performance of microbots are of paramount importance. This paper presents a critical analysis of the state-of-the-art literature related to pulsatile blood flow around microbots.…”
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“…As a central energy sensor, the AMP-activated protein kinase (AMPK) has recently been elucidated to play a paramount role in fat synthesis and catabolism, especially in regulating the energy expenditure of brown/beige adipose tissue and the browning of white adipose tissue (WAT). …”
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“…For this reason, it is of paramount importance to gain a deeper understanding of the structure–reactivity relationship in a-SiO(2) for the prediction of the optical properties of a glass based on its manufacturing parameters, and the realization of more efficient devices. …”
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“…With this ongoing global issue, vaccines are considered of paramount importance in curtailing the outbreak and probably a prime gamble to bring us back to ‘ordinary life’. …”
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“…Deciphering such interactions is thus paramount to understanding viral fitness in its natural hosts. …”
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“…Considering the complex nature of cork and the resulting peculiar compressive response, the present review article provides an overview of this paramount property, assessing the main parameters (anisotropy, temperature, strain rate, etc.) and the peculiar features (near-zero Poisson’s ratio and unique dimensional recovery) that characterize it in its natural state. …”
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“…CONCLUSION: Intra-operative examination of the cecum is paramount to rule out appendiceal anomalies and prevent medicolegal complications.…”
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“…The design and control to obtain the desirable optoelectronic properties of the halide perovskite nanocrystals, thus, remain paramount importance. The synthesis and stabilization of cesium lead bromide (CsPbBr(3)) nanoplatelets through ligand-assisted reprecipitation protocol (LARP) can indeed enable the manipulation of the layer thickness over the resulting nanoplatelets. …”
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“…Knowledge of spring waters’ chemical composition is paramount for both their use and their conservation. …”
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“…Understanding the genetic architecture of metabolic epilepsies is of paramount importance, both to current clinical practice and for the identification of further research directions. …”
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“…This work discloses a novel and paramount route to exploit PECH-based MIEMs for Li storage, as well as energy storage systems beyond Li.…”
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“…In the presented case, enhanced perfusion to the brain by way of an intact cord likely led to regained consciousness, initiation of breathing, and return of tone and reflexes minutes after birth. Paramount to our hypothesis is the importance of keeping the umbilical cord circulation intact during the first several minutes of life to accommodate physiologic neonatal transition for all newborns and especially for those most compromised infants.…”
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“…Identification of ionic liquids with low toxicity is paramount for applications in various domains. Traditional approaches used for determining the toxicity of ionic liquids are often expensive, and can be labor intensive and time consuming. …”
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“…A detailed description of these activation mechanisms is paramount to understanding how Hsp90-associated diseases develop.…”
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“…Accordingly, prompt identification of the extra-ocular etiology and a methodical understanding of the mechanisms of invasion and host-microbial interaction is of paramount importance for preventative and therapeutic interventions for vision-threatening conditions. …”
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“…Finally, one cannot overemphasize the paramount importance of human supervision, in order to optimize the use and take full advantage of the potential of AI approaches.…”
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“…These two models allow us to model unique electronic properties of graphene that could be paramount for the design of future graphene devices.…”
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