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  1. 2921
    “…For this reason, an accurate prediction of its behaviour is of paramount importance. In this work, the spotlight is on the cyclic response and low-cycle fatigue performance of this material, at room temperature. …”
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  2. 2922
    “…Thus, the measurement of loneliness is of paramount importance. The Three-Item Loneliness Scale (TILS) was designed to be used in large-population surveys as a quick measure of loneliness. …”
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  3. 2923
    “…Background and objectives: ischemic stroke (IS) is among the most frequent causes of death worldwide; thus, it is of paramount relevance to know predisposing factors that may help to identify and treat the high-risk subjects. …”
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  4. 2924
    “…Classifying cells in Pap smear images is very challenging, and it is still of paramount importance for cytopathologists. The Pap test is a cervical cancer prevention test that tracks preneoplastic changes in cervical epithelial cells. …”
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  5. 2925
    por Graykowski, David, Cudaback, Eiron
    Publicado 2021
    “…The critical nature of these varied functions makes the characterization of key roles played by microglia in neurodegenerative disorders, especially Alzheimer’s disease, of paramount importance. While genetic models and rudimentary pharmacologic approaches for microglial manipulation have greatly improved our understanding of central nervous system health and disease, significant advances in the selective and near complete in vitro and in vivo depletion of microglia for neuroscience application continue to push the boundaries of research. …”
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  6. 2926
    “…These factors suggest that face masks and social distance could be paramount in containing the pandemic. We examined the efficacy of each measure and the combination of both measures using an agent-based model within a closed space that approximated real-life interactions. …”
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  7. 2927
    “…In order to understand and control such devices, it is of paramount importance to understand the factors that determine ion flux at various conditions, including the synthesis potential. …”
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  8. 2928
    por Jamal, Faizi, Rosenzweig, Michael
    Publicado 2021
    “…Accurate characterization of the disease based on the nature of the precursor protein, organ involvement, and extent of disease is paramount to guide management. Cardiac amyloidosis is critical to understand because of its impact on prognosis and new treatment options available. …”
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  9. 2929
    “…High index of suspicion and prompt diagnosis is of paramount for reducing morbidity and mortality.…”
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  10. 2930
    “…It contributes to and extends all previously proposed naïve and aoristic temporal approximation methods and one recent study [1] that showed that the addition of historical crimes with accurately known time stamps to temporal approximation methods can outperform all traditional approximation methods. It is paramount to work with crime data that possess precise temporal information to conduct reliable (spatiotemporal) analysis and modeling. …”
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  11. 2931
  12. 2932
    “…However, to specifically target malignancies with minimal adverse effects on normal cells, a good understanding of TLS mechanisms in normal versus cancer cells is paramount. We show that in normal cells, TLS through cisplatin intrastrand cross-links is promoted by Polη- or Polι-dependent pathways, both of which require Rev1 as a scaffolding component. …”
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  13. 2933
    “…In this period of global pandemic caused by SARS-Cov-2, it is of paramount importance to recognize all risk factors that may increase the likelihood of infection. …”
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  14. 2934
    “…Privacy protection is paramount in conducting health research. However, studies often rely on data stored in a centralized repository, where analysis is done with full access to the sensitive underlying content. …”
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  15. 2935
    “…They are unfrequently associated with opportunistic infections and latent tuberculosis (TB) screening is paramount before immunosuppression. A 62-year-old man with psoriatic arthritis was under treatment with adalimumab for over 5 years. …”
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  16. 2936
    “…The exosome is a kind of extracellular vesicle (EV) from about 30 to 200 nm in diameter, contributing to the transfer of specific functional molecules, such as metabolites, proteins, lipids, and nucleic acids. The paramount role of exosomes in the formation and development of ESCC, which relies on promoting intercellular communication in the tumor microenvironment (TME), is manifested with immense amounts. …”
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  17. 2937
    “…Although exercise stress test risk is minimal with a <1% chance of causing heart block, physician awareness of potential complications is paramount for prompt recognition and treatment. Case Report: A 65-year-old-female with angina-like chest pain underwent an exercise stress test for ischemic heart disease evaluation. …”
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  18. 2938
    “…Understanding risk factors for disordered eating development is paramount to protecting the health and performance of these athletes. …”
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  19. 2939
    “…Knowing target regions undergoing strfuncti changes caused by behavioural interventions is paramount in evaluating the effectiveness of such practices. …”
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  20. 2940
    “…Understanding the mechanisms underlying AIH pathogenesis is therefore of paramount importance to develop more effective and well tolerated agents capable of restoring immunotolerance to liver autoantigens. …”
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