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  1. 3021
    “…Consequently, the clinical background of the patient and the pretest probability of HPA axis impairment become of paramount importance. We aimed to summarize the recent literature evidence in the conduction and interpretation of the ACTH stimulation test for the diagnosis of SAI to provide updated insights on its correct use in clinical practice.…”
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    ACTH Stimulation Test for the Diagnosis of Secondary Adrenal Insufficiency: Light and Shadow
  2. 3022
    “…SIMPLE SUMMARY: Non-invasive temperature monitoring during hyperthermia cancer treatment is of paramount importance. It allows physicians to verify the therapeutic temperature is reached in the treated area. …”
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    Hyperthermia Treatment Monitoring via Deep Learning Enhanced Microwave Imaging: A Numerical Assessment
  3. 3023
    “…Therefore, our findings emphasize the remarkable antioxidant and anticancer potential of OLE and GTE and suggest that chlorophylls are of paramount importance for the tumor-killing ability of such plant-derived extracts.…”
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    Chlorophyll Pigments of Olive Leaves and Green Tea Extracts Differentially Affect Their Antioxidant and Anticancer Properties
  4. 3024
    “…Although the condition is rare, early recognition is paramount. It ensures prompt appropriate intervention is administered, as conventional management for bradycardia as guided by advanced cardiac life support (ACLS) is ineffective in the BRASH syndrome. …”
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    Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome: A Rising Entity of Severe Bradycardia
  5. 3025
    “…In addition, toxic electrolytes used in LIBs pose concerns on environmental impacts if LIBs are not handled properly after decommissioned from EVs. Therefore, it is paramount to realize effective utilization of spent LIBs, where their remaining capacities can be reused in less demanding applications. …”
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    Sustainable Reuse and Recycling of Spent Li‐Ion batteries from Electric Vehicles: Chemical, Environmental, and Economical Perspectives
  6. 3026
    “…One of the clinical difficulties in diagnosing giant bullous emphysema is separating it from other etiologies like pneumothorax. It is paramount to differentiate giant bullous emphysema from pneumothorax as the management is completely different; both can, however, have similar clinical presentations and radiographic manifestations on initial assessment. …”
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    Cardiothoracic Surgery Management of Giant Bullous Lung Disease Initially Misdiagnosed as Pneumothorax: A Case Report
  7. 3027
    “…BACKGROUND: Redo mitral valve surgery using resternotomy after coronary artery bypass grafting (CABG) is challenging as previous CABG with patent internal thoracic artery (ITA) poses a risk of injury due to dense adhesion. It is paramount to have alternative method to minimize this risk. …”
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    Redo mitral surgery after coronary artery bypass grafts under hyperkalemic hypothermia using thoracotomy and axillary artery cannulation in a patient with functioning bilateral internal thoracic arteries and atheromatous aorta
  8. 3028
    “…CONCLUSION: Education and awareness regarding monkeypox vaccinations are of paramount importance. It is essential that clinical doctors are adequately aware of this disease, in order to avoid an uncontrolled situation, as experienced with COVID-19.…”
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    Monkeypox in Syria: Highlighting an awareness issue
  9. 3029
    “…In the field of biocatalysis, the implementation of sustainable processes such as enzyme immobilization or employment of environmentally friendly solvents, like Deep Eutectic Solvents (DESs) are of paramount importance. In this work, tyrosinase was extracted from fresh mushrooms and used in a carrier-free immobilization towards the preparation of both non-magnetic and magnetic cross-linked enzyme aggregates (CLEAs). …”
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    Tyrosinase Magnetic Cross-Linked Enzyme Aggregates: Biocatalytic Study in Deep Eutectic Solvent Aqueous Solutions
  10. 3030
    “…However, to improve the API properties by cocrystallization, coformer selection plays a paramount role. Selection of suitable coformers not only improves the drug’s physicochemical properties but also improves the therapeutic effectiveness and reduces side effects. …”
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    Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems
  11. 3031
    “…Detecting this exotic order in candidate materials is a subject of paramount importance, as the size of the excitonic gap in the band structure establishes the potential of this collective state for superfluid energy transport. …”
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    The spontaneous symmetry breaking in Ta(2)NiSe(5) is structural in nature
  12. 3032
    por Pessa, Joel E.
    Publicado 2023
    “…How cerebrospinal fluid (CSF) drains from the human brain is of paramount importance to cerebral health and physiology. …”
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    Identification of a novel path for cerebrospinal fluid (CSF) drainage of the human brain
  13. 3033
    “…CONCLUSIONS: Even in the endoscopic era, OPF still represents a paramount procedure that should be included in the rhino-surgeon’s armamentarium, in particular in patients with challenging pathologies and anatomy when previous endoscopic endonasal attempts have failed.…”
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    The role of the osteoplastic flap in the endoscopic era: a retrospective multicentre experience on revision surgery
  14. 3034
    “…Among estrogen’s non genomic responses regulation of calcium homeostasis and contraction and relaxation processes play paramount roles in ASM. On the other hand, disruption of calcium homeostasis has been closely associated with some ASM pathological mechanism. …”
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    Estrogenic Modulation of Ionic Channels, Pumps and Exchangers in Airway Smooth Muscle
  15. 3035
    “…Understanding the nature of molecular excitons in low-dimensional molecular solids is of paramount importance in fundamental photophysics and various applications such as energy harvesting, switching electronics and display devices. …”
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    In-plane and out-of-plane excitonic coupling in 2D molecular crystals
  16. 3036
    “…Perioperative optimization in surgery is paramount to the success of an operation. This especially applies to autologous breast reconstruction where small details can make the difference between success and failure. …”
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    Optimizing perioperative outcomes in autologous breast reconstruction
  17. 3037
    “…A greater emphasis on the mental and emotional well-being of frontline workers is paramount to the success of maintaining a strong and resilient health care workforce.…”
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    “If I Can’t Do It, Who Will?” Lived Experiences of Australian Emergency Nurses During the First Year of the COVID-19 Pandemic
  18. 3038
    “…Furthermore, the emergence and spread of antibiotic-resistant bacterial pathogens is of paramount public health concern. The likelihood of further spread is influenced by various factors. …”
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    Bakterielle Zoonosen mit Bedeutung für den öffentlichen Gesundheitsschutz in Deutschland – Vorkommen, Verbreitung und Übertragungswege
  19. 3039
    “…The active role of the patient in the therapeutic decision and the shared definition of LDL cholesterol targets are of paramount importance. The aim of this narrative review is to summarize evidence on current levels of adherence to lipid-lowering strategies, the causes of the lack of adequate adherence and possible physician-applicable strategies to improve it.…”
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    Challenges in Improving Adherence to Diet and Drug Treatment in Hypercholesterolemia Patients
  20. 3040
    “…The research disclosed herein can offer new insights into the development of untethered and energy-efficient artificial aerial vehicles that are of paramount significance for many applications from environmental monitoring and wireless communication to future solar sail and robotic spacecraft.…”
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    Light-driven dandelion-inspired microfliers
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