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  1. 3301
    “…CONCLUSION: Timely diagnosis is paramount to avoid limb- and life-threatening sequelae; surgeons should keep strong vigil to administer the timely intervention. …”
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    Misery of Orthopaedic Surgeon: Delayed Diagnosis of Pseudoaneurysm of Profunda Femoris Artery Following Fixation of Intertrochanteric Femoral Fracture: A Case Report and Review of Literature
  2. 3302
    “…Understanding the determinants of vaccine hesitancy is paramount to reinstate confidence in immunizations. …”
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    Vaccine Hesitancy: Characteristics of the Refusal of Childhood Vaccination in a Peruvian Population
  3. 3303
    “…However, these micronutrients are paramount for preterms’ health: LCPUFAs can promote retinal and brain development while calcium and phosphorus supplementation is essential to prevent preterms’ metabolic bone disease (MBD). …”
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    Overview of Important Micronutrients Supplementation in Preterm Infants after Discharge: A Call for Consensus
  4. 3304
    “…Thus, the choice of the right mixing device is paramount for compounding pharmacies. In this paper, we evaluated the mixing efficacy of a new 3-axis mixer device and determined its optimal working conditions. …”
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    Ensuring Homogeneity in Powder Mixtures for Pharmaceuticals and Dietary Supplements: Evaluation of a 3-Axis Mixing Equipment
  5. 3305
    “…Intestinal microbiota is established to be a crucial element in the control of human health, and keeping the symbiotic relationship between the human body and intestinal microbes will have paramount importance. A number of investigations illustrated that many chronic diseases are associated with intestinal micro-ecological disorders implying intestinal floras as an important component among the environmental factors, and perturbations in their composition are correlated with metabolic disorders, including obesity and diabetes mellitus (DM). …”
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    Microbial Ecosystem in Diabetes Mellitus: Consideration of the Gastrointestinal System
  6. 3306
    “…As novel fields like high‐entropy alloys emerge, understanding these effects on the atomic structure level is paramount: What atoms near the binding site determine the reactivity of the alloy surface? …”
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    What Atomic Positions Determines Reactivity of a Surface? Long‐Range, Directional Ligand Effects in Metallic Alloys
  7. 3307
    “…Structural health monitoring for offshore wind turbine foundations is paramount to the further development of offshore fixed wind farms. …”
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    Unsupervised Damage Detection for Offshore Jacket Wind Turbine Foundations Based on an Autoencoder Neural Network
  8. 3308
    “…While optical techniques, scattering, and spectroscopy are often used to complement rheological observations, coupling them in situ to allow simultaneous observation is paramount to fully understand the details of CNC assembly from liquid to solid. …”
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    Cellulose Nanocrystal Liquid Crystal Phases: Progress and Challenges in Characterization Using Rheology Coupled to Optics, Scattering, and Spectroscopy
  9. 3309
    “…With the known increased risk of colorectal cancer in IBD, although prevention strategies continue to develop, regular surveillance for early detection of neoplasia continue to be paramount in IBD patients’ care. It is thanks to evolving technology and visualization techniques that surveillance strategies are continuously advancing. …”
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    Evolving role of endoscopy in inflammatory bowel disease: Going beyond diagnosis
  10. 3310
    “…Conclusion: Treatment of microbial keratitis with those antibiotics that the organism is most sensitive to is of paramount importance today, where we often find patients on a cocktail of eye drops, which leads to further resistance and vision deterioration. …”
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    Infectious crystalline keratitis induced by Citrobacter
  11. 3311
    “…Obesity is a risk factor for development of metabolic diseases and cognitive decline; therefore, obesity prevention is of paramount importance. Neuronal mitochondrial dysfunction induced by oxidative stress is an important mechanism underlying cognitive decline. …”
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    Olive leaf extract prevents obesity, cognitive decline, and depression and improves exercise capacity in mice
  12. 3312
    “…ABSTRACT: As the reality of pandemic threats challenges humanity, exemplified during the ongoing SARS-CoV-2 infections, the development of vaccines targeting these etiological agents of disease has become increasingly critical. Of paramount concern are novel and reemerging pathogens that could trigger such events, including the plague bacterium Yersinia pestis. …”
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    Plague vaccines: new developments in an ongoing search
  13. 3313
    “…Early differential diagnosis is of paramount importance for optimization of treatment. …”
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    DCX and CRABP2 are candidate genes for differential diagnosis between pre‐chemotherapy embryonic and alveolar rhabdomyosarcoma in pediatric patients
  14. 3314
    “…Understanding the underlying similarities and differences between men and women is paramount to providing adequate care and prognostication to patients of either gender. …”
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    The role of gender in non-small cell lung cancer: a narrative review
  15. 3315
    “…The state-of-the-art research level and paramount demand in modern society recall the rapid development of a new generation of tunable antimicrobials. …”
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    Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials
  16. 3316
    por Hoffman, Kurt Leroy
    Publicado 2021
    “…Animal models have been paramount for elucidating the actions of CBD and the function of the endocannabinoid system and for identifying novel pharmacological targets, such as cannabinoid receptors and anandamide. …”
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    From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia
  17. 3317
    “…Monitoring the burden and spread of infection with the new coronavirus SARS-CoV-2, whether within small communities or in large geographical settings, is of paramount importance for public health purposes. Serology, which detects the host antibody response to the infection, is the most appropriate tool for this task, since virus-derived markers are most reliably detected during the acute phase of infection. …”
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    Highly versatile antibody binding assay for the detection of SARS-CoV-2 infection
  18. 3318
    “…Correct calculation of the maximum safe dose is therefore paramount in preventing such complications. Different solutions have already emerged to support anesthesiologists but are seldom used in clinical practice as they require either access to a computer or specific documents to be at hand. …”
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    Development and Preliminary Validation of LoAD Calc, a Mobile App for Calculating the Maximum Safe Single Dose of Local Anesthetics
  19. 3319
    por Rammohan, Ashwin, Rela, Mohamed
    Publicado 2021
    “…In living donor liver transplantation (LDLT) the safety of the live donor (LD) is of paramount importance. Despite all efforts, the morbidity rates approach 25%-40% with conventional open donor hepatectomy (DH) operations. …”
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    Robotic donor hepatectomy: Are we there yet?
  20. 3320
    “…Synapses undergo diverse forms of plasticity, resulting in long-term, persistent changes in synapse strength, which are paramount for learning, memory, and cognition. It is now well-established that local translation of numerous synaptic proteins is essential for many forms of synaptic plasticity, and much work has gone into deciphering the strategies that neurons use to regulate activity-dependent protein synthesis. …”
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    The Coordination of Local Translation, Membranous Organelle Trafficking, and Synaptic Plasticity in Neurons
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