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  1. 3621
    “…Such endeavors hold paramount significance for personalized therapeutic approaches and the more effective management of HNSCC patients.…”
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    Deciphering the role of HPV-mediated metabolic regulation in shaping the tumor microenvironment and its implications for immunotherapy in HNSCC
  2. 3622
    “…It is evident that this diverse range of strategies results not only from a long evolutionary history, but is also of paramount importance for refining gene expression and metabolic modulation. …”
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    A Molecular Orchestration of Plant Translation under Abiotic Stress
  3. 3623
    “…Identifying factors associated with sarcopenia is of paramount significance, particularly considering that some of them can be modified and managed. …”
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    Factors Associated with Sarcopenia among Elderly Individuals Residing in Community and Nursing Home Settings: A Systematic Review with a Meta-Analysis
  4. 3624
    “…Consequently, examining the evolution of China’s interaction with Middle Eastern nations over the past decade is of paramount significance for future development. This study utilizes the GDELT database to construct formulas for measuring event impact and bilateral relationship intensity. …”
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    Evolution of China’s interaction with Middle Eastern countries under the Belt and Road Initiative
  5. 3625
    “…Early intervention is of paramount importance and further research is needed to evaluate the long-term effects of OT interventions in patients with ATTRv. …”
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    Occupational practice in patients with hereditary transthyretin amyloidosis, a qualitative study
  6. 3626
    “…A technically sound colorectal anastomosis is paramount in optimising outcomes and reducing complications such as anastomotic leak which can lead to prolonged hospital stay, repeated operations, stoma formation, anastomotic stricture formation and even mortality in patients. …”
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    Surgical considerations for the “perfect” colorectal anastomosis
  7. 3627
    “…Hence, a meticulous and comprehensive hygienic strategy remains paramount in our collective efforts to combat this pandemic.…”
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    COVID-19 on the spectrum: a scoping review of hygienic standards
  8. 3628
    “…Although NSLAB aromatic properties are paramount, other phenotypic traits need to be considered for their use as adjunct cultures, such as the capability to endure technological parameters encountered during cheesemaking. …”
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    Lacticaseibacillus Strains Isolated from Raw Milk: Screening Strategy for Their Qualification as Adjunct Culture in Cheesemaking
  9. 3629
    “…Identifying interspecies interactions in mixed-species biofilms is a key challenge in microbial ecology and is of paramount importance given that interactions govern community functionality and stability. …”
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    Dynamic social interactions and keystone species shape the diversity and stability of mixed-species biofilms – an example from dairy isolates
  10. 3630
    “…However, a comprehensive assessment of the sustainability factors pertaining to host families remains a critical area awaiting exploration. This is paramount for ensuring the long-term viability of homestays and fostering economic benefits within rural communities. …”
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    Assessing the sustainability of the homestay industry for the East Coast of Malaysia using the Delphi approach
  11. 3631
    “…These interactions are paramount in anti‐tumor immunity, further promoting the formation of an immunosuppressive microenvironment and resistance to immunotherapy. …”
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    Metabolic reprogramming, autophagy, and ferroptosis: Novel arsenals to overcome immunotherapy resistance in gastrointestinal cancer
  12. 3632
    “…We summarize the latest advancements in potential therapeutic drugs that specifically target these signaling pathways and paramount targets, covering both preclinical studies and clinical trials. …”
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    The pathogenesis and potential therapeutic targets in sepsis
  13. 3633
    “…Notably, the “Other-focused” theme emphasizes the pursuit of group harmony and the fulfillment of group responsibilities, highlighting the paramount role of “relationships” in the study of happiness within collectivist cultures. …”
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    Pursuing Harmony and Fulfilling Responsibility: A Qualitative Study of the Orientation to Happiness (OTH) in Chinese Culture
  14. 3634
    “…In conclusion, we underscore the paramount significance of nuclear metabolic signaling in cancer biology and enumerate potential therapeutic targets, associated pharmacological interventions, and implications for clinical applications. …”
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    Potential therapies targeting nuclear metabolic regulation in cancer
  15. 3635
    por Daybog, Itay, Kolodny, Oren
    Publicado 2023
    “…Moreover, gnotobiotic individuals exhibit highly deleterious phenotypes, supporting the view that the microbiome is paramount to host fitness. However, the introduction of almost arbitrarily selected microbiota into the system often achieves a significant rescue effect of the deleterious phenotypes. …”
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    A computational framework for resolving the microbiome diversity conundrum
  16. 3636
    “…Training is imperative; it is of paramount importance for our future medical professionals to be self-aware of their emotional triggers.…”
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    Intimate Partner Violence: Using Standardized Patients to Improve Trauma-Informed Care in the era of the Covid-19 Pandemic
  17. 3637
    “…Thus, reproducible methods for in vitro small RNA cloning are of paramount importance and will remain so into the foreseeable future. …”
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    Methodologies for In Vitro Cloning of Small RNAs and Application for Plant Genome(s)
  18. 3638
    “…Methods to characterise the length distribution of nano-scale linear aggregates such as amyloid fibrils are of paramount importance both in understanding the biological impact of these aggregates and in controlling their mechanical properties as potential nano-materials. …”
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    Amyloid fibril length distribution quantified by atomic force microscopy single-particle image analysis
  19. 3639
    “…Understanding measures of arousal is, therefore, paramount to further theoretical and practical advances in the study of human sexuality. …”
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    Agreement of Self-Reported and Genital Measures of Sexual Arousal in Men and Women: A Meta-Analysis
  20. 3640
    “…As energy conservation is paramount to these birds, minimising the costs of moving around when resources are limited would appear to be a key adaptation crucial for their survival in the barren Arctic environment.…”
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    Reduced Metabolic Cost of Locomotion in Svalbard Rock Ptarmigan (Lagopus muta hyperborea) during Winter
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