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  1. 3761
    “…In conclusion, researchers' technological competency, along with meticulous methods and reports pertinent to software, hardware, and VRISE, are paramount to ensure the health and safety standards and the reliability of neuroscientific results.…”
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    Technological Competence Is a Pre-condition for Effective Implementation of Virtual Reality Head Mounted Displays in Human Neuroscience: A Technological Review and Meta-Analysis
  2. 3762
    “…Thus, the current study elucidates the pathobiology of taxane chemotherapy‐induced alopecia, highlights the paramount importance of epithelial stem/progenitor cell‐protective therapy in taxane‐based oncotherapy, and provides preclinical proof‐of‐principle in a healthy human (mini‐) organ that G1 arrest therapy can limit taxane‐induced tissue damage.…”
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    CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia
  3. 3763
    “…In selected patients, as those with persistent Gram-negative bacteremia or severe sepsis/septic shock, echocardiography is of paramount importance for the diagnosis of Gram-negative endocarditis and should be included in our diagnostic algorithm of patient’s evaluation.…”
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    Escherichia coli Endocarditis Presenting With Septic Shock in an Immunocompetent Female Patient
  4. 3764
    “…Environment perception is crucial for the safe navigation of vehicles and robots to detect obstacles in their surroundings. It is also of paramount interest for navigation of human beings in reduced visibility conditions. …”
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    INSPEX: Optimize Range Sensors for Environment Perception as a Portable System
  5. 3765
    “…The Wnt signaling pathway is of paramount importance for development and disease. However, the tissue-specific regulation of Wnt pathway activity remains incompletely understood. …”
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    Wnt activator FOXB2 drives the neuroendocrine differentiation of prostate cancer
  6. 3766
    “…Understanding how these pathways are regulated in Plasmodium and identifying differences to the host is paramount to selectively interfering with parasites. …”
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    Nedd8 hydrolysis by UCH proteases in Plasmodium parasites
  7. 3767
    “…In the light of recent advances in the immunotherapy field for breast cancer (BC) treatment, especially in the triple‐negative subtype, the identification of reliable biomarkers capable of improving patient selection is paramount, because only a portion of patients seem to derive benefit from this appealing treatment strategy. …”
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    Programmed Cell Death Ligand 1 in Breast Cancer: Technical Aspects, Prognostic Implications, and Predictive Value
  8. 3768
    “…Understanding the structure and the dynamics of networks is of paramount importance for many scientific fields that rely on network science. …”
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    A detailed characterization of complex networks using Information Theory
  9. 3769
    “…Development of sensitive methods for the determination of E. coli bacteria contamination in water distribution systems is of paramount importance to ensure the microbial safety of drinking water. …”
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    Dark Field Microscopy-Based Biosensors for the Detection of E. coli in Environmental Water Samples
  10. 3770
    “…Elucidating pathomechanism and identifying novel therapeutic targets are of paramount importance. Lemur tyrosine kinase 2 (LMTK2) is involved in several physiological and pathological cellular processes. …”
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    Neuropathological characterization of Lemur tyrosine kinase 2 (LMTK2) in Alzheimer’s disease and neocortical Lewy body disease
  11. 3771
    “…Recent availability of MRI‐guided linear accelerators has introduced a number of clinical challenges, particularly in the context of online plan adaptation. Paramount among these is verification of plan quality prior to patient treatment. …”
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    Commissioning and performance evaluation of RadCalc for the Elekta unity MRI‐linac
  12. 3772
    por Yan, Yao, Liu, Yang, Liao, Maolin
    Publicado 2017
    “…When the capsule speed is paramount, one can employ the two-sided capsule with a weak left constraint under large amplitude of excitation. …”
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    A comparative study of the vibro-impact capsule systems with one-sided and two-sided constraints
  13. 3773
    “…[Image: see text] Optical sensing in the mid- and long-wave infrared (MWIR, LWIR) is of paramount importance for a large spectrum of applications including environmental monitoring, gas sensing, hazard detection, food and product manufacturing inspection, and so forth. …”
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    Mid- and Long-Wave Infrared Optoelectronics via Intraband Transitions in PbS Colloidal Quantum Dots
  14. 3774
    “…With the prospect of new viable therapies, accurate and timely diagnosis becomes paramount, as well as identification of fetuses at risk for neurodevelopmental sequelae. …”
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    The MRI spectrum of congenital cytomegalovirus infection
  15. 3775
    por Lommatzsch, Sherstin T.
    Publicado 2020
    “…As there is no cure for either condition, prevention and control of infection is paramount. Such an undertaking incorporates patient/family and healthcare team education, immunoprophylaxis, microorganism source control, antimicrobial chemoprophylaxis, organism eradication, daily pulmonary disease management, and, in some cases, thoracic surgery. …”
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    Infection prevention and chronic disease management in cystic fibrosis and noncystic fibrosis bronchiectasis
  16. 3776
    “…Nevertheless, taking conditions such as ageing, sex, comorbidities and co‐medication into account may be of paramount importance during the design of pre‐clinical and clinical studies testing mitoprotective drugs.…”
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    Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST‐segment elevation myocardial infarction
  17. 3777
    “…Over the past 50 years, whilst the training of competent professionals for their work has been paramount, this has paralleled the need to engage with the rapid and complex changes in R&D technologies, patient and healthcare system needs, and the ethical and regulatory obligations applied to the development of medicines throughout their lifecycle. …”
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    Evolution of the Development of Core Competencies in Pharmaceutical Medicine and Their Potential Use in Education and Training
  18. 3778
    “…Although it will always be necessary to translate and validate the observations seen in vitro to the patient or animal, the ability to investigate the role(s) of individual variables free from confounders is paramount toward increasing our understanding of the physiology and their role in disease. …”
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    Tissue Culture Models
  19. 3779
    “…Quick diagnostic tests and specific treatments for SARS are not yet available; thus, prevention is of paramount importance to contain its global spread. …”
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    Factors influencing the wearing of facemasks to prevent the severe acute respiratory syndrome among adult Chinese in Hong Kong
  20. 3780
    “…INTRODUCTION: Antibiotic misuse is the paramount factor for antibiotic resistance. Tamale Teaching Hospital (TTH), located in Ghana’s Northern Region, is the biggest tertiary hospital in the Northern half of the country and consequently one of the biggest prescribers of antibiotics. …”
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    A cross-sectional study on antibiotic prescription in a teaching hospital in Ghana
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