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  1. 3921
    “…It is, therefore, of paramount importance to assess the functionality of the DNA repair apparatus prior to any genotoxic treatment when the exact molecular cause of the disease is unknown. …”
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    Inborn errors of immunity caused by defects in the DNA damage response pathways: Importance of minimizing treatment‐related genotoxicity
  2. 3922
    “…Our analysis highlights the paramount importance of maintaining high population immunity, preferably by booster uptake, and the role of quarantine and testing to control the spread of SARS CoV-2.…”
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    Quarantine and serial testing for variants of SARS-CoV-2 with benefits of vaccination and boosting on consequent control of COVID-19
  3. 3923
    “…The recent emergence of multiple SARS‐CoV‐2 variants has caused considerable concern due to both reduced vaccine efficacy and escape from neutralizing antibody therapeutics. It is, therefore, paramount to develop therapeutic strategies that inhibit all known and future SARS‐CoV‐2 variants. …”
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    Clinical grade ACE2 as a universal agent to block SARS‐CoV‐2 variants
  4. 3924
    “…The necessity to identify candidates with high-quality uterine vasculature is paramount. We retrospectively evaluated and compared the imaging results with actual vascular findings from the back table. …”
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    Radiologic Evaluation of Uterine Vasculature of Uterus Transplant Living Donor Candidates: DUETS Classification
  5. 3925
    “…As such, it represents a paramount example of collective coordination action on social media, resulting in large-scale consensus formation and significant market impact. …”
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    Self-induced consensus of Reddit users to characterise the GameStop short squeeze
  6. 3926
    por Lee, Woojong, Suresh, M.
    Publicado 2022
    “…Eliciting balanced humoral and T cell-mediated immunity is paramount to defend against diseases caused by complex intracellular pathogens, such as tuberculosis, malaria, and AIDS. …”
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    Vaccine adjuvants to engage the cross-presentation pathway
  7. 3927
    “…Communication skills are paramount in all areas of medicine but particularly in psychiatry due to the challenges posed by mental health patients and the essential role of communication from diagnosis to treatment. …”
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    Communication skills in psychiatry for undergraduate students: A scoping review
  8. 3928
    “…Ultrathin films with high dielectric constants (high-k) are of paramount interest for applications as gate layers in current and future integrated circuits. …”
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    Phonon confinement and interface lattice dynamics of ultrathin high-k rare earth sesquioxide films: the case of Eu(2)O(3) on YSZ(001)
  9. 3929
    “…Implementing management practices for the control of invasive species can be a complex task with multiple dimensions, where the identification of stakeholders and drivers of those practices is of paramount importance. The invasive hornet Vespa velutina has spread across Europe and Asia from its native range in SE Asia in recent years. …”
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    Of Fears and Budgets: Strategies of Control in Vespa velutina Invasion and Lessons for Best Management Practices
  10. 3930
    “…Minimising adverse events is paramount because research participants receive no clinical benefit and often need repeat procedures. …”
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    Cerebrospinal fluid sampling for research of Alzheimer’s disease and other neurodegenerative diseases when lumbar punctures are performed by anaesthetists
  11. 3931
    “…In this review, the current status and future prospects of the use of molecular imaging as an instrument to help realize precision surgery is addressed with focus on the main components that form the conceptual basis of intraoperative molecular imaging. Paramount for successful interventions is the relevance and accessibility of surgical targets. …”
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    The current status and future prospects for molecular imaging-guided precision surgery
  12. 3932
    “…Hand osteoarthritis is the most common joint condition and is associated with significant morbidity. It is of paramount importance that patients are thoroughly assessed and examined when complaining of hand stiffness, pain, deformity or disability and that the patient’s concerns and expectations are addressed by the healthcare professional. …”
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    Management of hand osteoarthritis: from an US evidence-based medicine guideline to a European patient-centric approach
  13. 3933
    “…Nuanced understanding of seasonal movements of partially migratory birds is paramount to species and habitat conservation. Using nascent statistical methods, we identified migratory strategies of birds outfitted with radio-frequency identification (RFID) tags detected at RFID feeders in two sites in California, USA. …”
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    Quantifying phenology and migratory behaviours of hummingbirds using single-site dynamics and mark-detection analyses
  14. 3934
    “…Developing efficient catalysts is of paramount importance to oxygen evolution, a sluggish anodic reaction that provides essential electrons and protons for various electrochemical processes, such as hydrogen generation. …”
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    Enhanced oxygen evolution over dual corner-shared cobalt tetrahedra
  15. 3935
    “…Accurately predicting contact between our bodies and environmental objects is paramount to our evolutionary survival. It has been hypothesized that multisensory neurons responding both to touch on the body, and to auditory or visual stimuli occurring near them—thus delineating our peripersonal space (PPS)—may be a critical player in this computation. …”
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    A normative model of peripersonal space encoding as performing impact prediction
  16. 3936
    “…The role of amphiphilicity in polysaccharide-based superabsorbent polymers is paramount in determining material properties. While the performance of freeze-dried polymers is improved by maximizing hydrophilicity, this may not be the case for evaporative-dried polymers. …”
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    Modulating superabsorbent polymer properties by adjusting the amphiphilicity
  17. 3937
    “…Thus, identification of novel prognostic indicators to stratify risk in patients with heart failure is of paramount importance. The spleen is emerging as a potential novel prognostic indicator for heart failure. …”
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    The cardiosplenic axis: the prognostic role of the spleen in heart failure
  18. 3938
    “…BACKGROUND: For institutions offering global health programs, the safety of trainees during clinical rotations at international sites is paramount. Current guidelines for global health electives recommend pre-departure training and safety-net resources, yet their advice on managing unanticipated problems is limited. …”
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    Managing the Unpredictable: Recommendations to Improve Trainee Safety During Global Health Away Electives
  19. 3939
    “…Maintaining genomic integrity in post-mitotic neurons in the human brain is paramount because these cells must survive for an individual’s entire lifespan. …”
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    The two faces of DNA oxidation in genomic and functional mosaicism during aging in human neurons
  20. 3940
    “…Supporting countries to use regularly collected data and adopt a common definition is paramount to tackling the importation of malaria cases and achieving elimination goals set forth by the World Health Organization.…”
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    Imported malaria definition and minimum data for surveillance
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