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  1. 4081
    “…Knowing which genes are essential for the survival of eukaryotic organisms is paramount for an understanding of the basic mechanisms of life, and could assist in identifying intervention targets in eukaryotic pathogens and cancer. …”
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  2. 4082
    por Rensel, Mary
    Publicado 2019
    “…Multiple sclerosis (MS) presenting in the pediatric years can lead to landmark disability levels younger in life than adult onset MS and so therefore early and effective treatment remains paramount for long-term outcomes. The goals of MS therapeutics in adults have widened to address multiple mechanisms: anti-inflammatory, neuroprotective, and myelin repair, yet the optimal paradigm for MS therapies in the pediatric population is not known. …”
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  3. 4083
    “…Volleyball serves constitute an important example for a self-controlled sequence of actions in sports that is difficult to improve. It is therefore paramount to investigate whether and how conveying self-control strategies to athletes affects their service performance. …”
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  4. 4084
    “…Clinker reduction in cementitious binders is of paramount importance today, and nanotechnology has extended permissible limits. …”
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  5. 4085
    por Ombelet, W, Onofre, J
    Publicado 2019
    “…The initiative of African Network and Registry for Assisted Reproductive Technology (ANARA) to register all IVF cycles in Africa needs our support and will be of paramount importance in the future. The hurdles to implement ART in most African countries are numerous and although more and more IVF centres are founded, the accessibility to ART remains very low.…”
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  6. 4086
    “…To understand how toxicity evolved in this family, it is paramount to elucidate the pathways of alkaloid processing (absorption, metabolism, and sequestering). …”
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  7. 4087
  8. 4088
    “…In light of this, dietary approaches are of paramount importance. Whole‐food plant‐based diets emphasizing grains, legumes, vegetables, fruits and nuts and excluding most (or all) animal products have recently experienced a significantly increased interest. …”
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  9. 4089
    “…The analyses of animal surveillance data are therefore of paramount importance for public health authorities to identify the appropriate control measure and intervention strategies in case of epidemics. …”
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  10. 4090
    “…In order to develop standardized clinical protocols, it is paramount to have a full characterization of the stem cell preparations. …”
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  11. 4091
    “…Precise, fast, reliable, and complex determination of all components of silymarin preparations is paramount for assessing its pharmacological quality. …”
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  12. 4092
    “…While presently global H(2) production is predominated by fossil‐fuel feedstocks, for future widespread utilization it is of paramount importance to produce H(2) in a decarbonized manner. …”
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  13. 4093
    “…She had a pachymetry of 238 μm OD and 254 μm OD and 254  CONCLUSIONS: Long-term follow-up of children diagnosed with Brittle Cornea Syndrome is paramount to minimize the morbidity of corneal rupture and late-onset extraocular conditions.…”
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  14. 4094
    “…In this context, specific proteins that interact with and bind to MAR sequences called MAR binding proteins (MARBPs), are of paramount importance, as these sequences spool the proteins that regulate transcription, replication, repair and recombination. …”
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  15. 4095
    “…Early recognition and diagnosis with prompt withdrawal of the culprit drug is paramount. Corticosteroid therapy is widely accepted as the cornerstone of DIDMOHS management. …”
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  16. 4096
    “…The interwoven function of tumor-suppressor protein p53-linked lncRNAs in the ovarian cancer paradigm is of paramount importance. Several lncRNAs operate as p53 regulators or effectors and modulates a diverse array of functions either by participating in various signaling cascades or via interaction with different proteins. …”
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  17. 4097
    “…Understanding the information-seeking behaviours of the public is paramount for providing sound nutrition advice. This research aims to identify who learners in a nutrition-focused Massive Open Online Course (MOOC) turn to for nutrition information, and how they discuss the information they find. …”
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  18. 4098
    por Abduljalil, J.M., Abduljalil, B.M.
    Publicado 2020
    “…Asymptomatic carrier state is of paramount importance because of carriers' ability to spread the infection and to shed the virus into the air and surroundings. …”
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  19. 4099
    “…As climate change progresses, understanding the impact on human health associated with the temperature and air pollutants has been paramount. However, the predicted effect on temperature associated with particulate matter (PM(10)) is not well understood due to the difficulty in predicting the local and regional PM(10). …”
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  20. 4100
    “…Due to the morbid and progressive nature of opportunistic fungal infections, early diagnosis is paramount for effective disease management. Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI) and Sanger sequencing are useful methods for rapid diagnosis of unusual fungal pathogens. …”
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