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  1. 4321
    “…Mining massive amounts of transcript data for alternative splicing information is paramount to help understand how the maturation of RNA regulates gene expression. …”
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    Unconstrained mining of transcript data reveals increased alternative splicing complexity in the human transcriptome
  2. 4322
    “…The identification and comparison of miRNAs in metazoan species are therefore paramount for our understanding of the evolution of body plans. …”
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    Functional Shifts in Insect microRNA Evolution
  3. 4323
    “…Delineating the signaling pathways that underlie ESC pluripotency is paramount for development of ESC applications in both the research and clinical settings. …”
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    Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene Expression
  4. 4324
    “…The cell type specificity of the reactions is the foundation of immunological research, and capturing this specificity is of paramount importance when using pathway-based analyses to decipher complex immunological datasets. …”
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    DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells
  5. 4325
    por Sa, Juliana M, Twu, Olivia
    Publicado 2010
    “…The >50% SVMNT haplotype prevalence in Angola represents a threat to the rise and spread of amodiaquine resistance. It is paramount to monitor pfcrt haplotypes in every country currently using amodiaquine and to re-evaluate current combination therapies in areas where SVMNT type parasites are prevalent.…”
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    Protecting the malaria drug arsenal: halting the rise and spread of amodiaquine resistance by monitoring the PfCRT SVMNT type
  6. 4326
    por Sexton, Alexis R
    Publicado 2011
    “…In order to determine the paramount distribution method, this review assessed literature on recent insecticide treated bed net distribution programmes throughout sub-Saharan Eastern Africa. …”
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    Best practices for an insecticide-treated bed net distribution programme in sub-Saharan eastern Africa
  7. 4327
    por John, Ime A, Lawoko, Stephen
    Publicado 2010
    “…Understanding the readiness of healthcare providers to screen for IPV is therefore paramount. The Domestic Violence Healthcare Provider Survey Scales (DVHPSS) is a previously validated, comprehensive scale to study readiness of healthcare providers to screen for IPV. …”
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    Assessment of the structural validity of the domestic violence healthcare providers’ survey questionnaire using a Nigerian sample
  8. 4328
    “…The gathering of researchers investigating fundamental pathobiology of ovarian cancer and the clinicians who treat patients with this insidious disease is paramount to meeting the challenges we face. Since 2002, the Canadian Conference on Ovarian Cancer Research, held every two years, has served this essential purpose. …”
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    On the path to translation: Highlights from the 2010 Canadian Conference on Ovarian Cancer Research
  9. 4329
    “…This novel study has significantly expanded the sphere of knowledge concerning berberine's pharmacological effects, beginning at its paramount initial interaction with the TATA box.…”
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    Comprehensive Study in the Inhibitory Effect of Berberine on Gene Transcription, Including TATA Box
  10. 4330
    “…PURPOSE: The control of nausea and vomiting induced by chemotherapy is paramount for overall treatment success in cancer patients. …”
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    Single-dose palonosetron for prevention of chemotherapy-induced nausea and vomiting in patients with aggressive non-Hodgkin's lymphoma receiving moderately emetogenic chemotherapy containing steroids: results of a phase II study from the Gruppo Italiano per lo Studio dei Linfomi (GISL)
  11. 4331
    “…Identification of the most critical windows of developmental vulnerability is paramount to understanding when and under what circumstances a child is at elevated risk for autism. …”
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    Environmental risk factors for autism
  12. 4332
    “…BACKGROUND: Considering that the costs of cellulases and hemicellulases contribute substantially to the price of bioethanol, new studies aimed at understanding and improving cellulase efficiency and productivity are of paramount importance. Aspergillus niger has been shown to produce a wide spectrum of polysaccharide hydrolytic enzymes. …”
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    Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse
  13. 4333
    “…The ability of spines to rapidly alter their shape, size, number and receptor content in response to stimulation is considered to be of paramount importance during the development of synaptic plasticity. …”
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    Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity
  14. 4334
    “…BACKGROUND: Structural insight from transcription factor-DNA (TF-DNA) complexes is of paramount importance to our understanding of the affinity and specificity of TF-DNA interaction, and to the development of structure-based prediction of TF binding sites. …”
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    Benchmarks for flexible and rigid transcription factor-DNA docking
  15. 4335
    “…BACKGROUND: All cultural groups in the world place paramount value on interpersonal trust. Existing research suggests that although accurate judgments of another's trustworthiness require extensive interactions with the person, we often make trustworthiness judgments based on facial cues on the first encounter. …”
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    Similarities and Differences in Chinese and Caucasian Adults' Use of Facial Cues for Trustworthiness Judgments
  16. 4336
    “…Understanding of the parameters controlling phytoplankton is paramount, as it affects the functioning of the Southern Ocean, its marine resources and ultimately the global carbon cycle.…”
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    Exploring the Link between Micronutrients and Phytoplankton in the Southern Ocean during the 2007 Austral Summer
  17. 4337
    “…Identification of specific signalling pathways driving luminal B biology is paramount to improve treatment. We have studied 100 luminal breast tumours by combined analysis of genome copy number aberrations and gene expression. …”
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    ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
  18. 4338
    “…Throughout the process, maintaining a dialogue between the treating physicians, the paramedical staff, the child, and his parents is of paramount importance to optimize the care of these children with complex disease and evolving medical status.…”
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    The critically-ill pediatric hemato-oncology patient: epidemiology, management, and strategy of transfer to the pediatric intensive care unit
  19. 4339
    “…Within the cerebellum, neuronal degeneration and/or dysfunction has been associated with many diseases, including several forms of cerebellar ataxia, since normal cerebellar function is paramount for proper motor coordination, balance, and motor learning. …”
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    Monitoring Performance Degradation of Cerebellar Functions Using Computational Neuroscience Methods: Implications on Neurological Diseases
  20. 4340
    “…In the quest for producing an effective, clinically relevant therapeutic agent, scalability, repeatability, and stability are paramount. In this paper, gold nanoparticles (GNPs) with precisely controlled near-infrared (NIR) absorption are synthesized by a single-step reaction of HAuCl(4) and Na(2)S(2)O(3) without assistance of additional templates, capping reagents, or seeds. …”
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    Tunability and stability of gold nanoparticles obtained from chloroauric acid and sodium thiosulfate reaction
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