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  1. 4441
    “…This work highlights the paramount importance of testing transgenic lines in field trials.…”
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    Overexpression of a pine Dof transcription factor in hybrid poplars: A comparative study in trees growing under controlled and natural conditions
  2. 4442
    “…Meanwhile, establishing rational design guidelines for 3-D nanostructured solar cells with the balanced electrical and optical performance are of paramount importance and in urgent need. Herein, regular arrays of 3-D nanospikes (NSPs) were fabricated on flexible aluminum foil with a roll-to-roll compatible process. …”
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    Roll-to-roll fabrication of large scale and regular arrays of three-dimensional nanospikes for high efficiency and flexible photovoltaics
  3. 4443
    “…A precise immune response is essential for cellular homeostasis and animal survival. The paramount importance of its control is reflected by the fact that its non-specific activation leads to inflammatory events that ultimately contribute to the appearance of many chronic diseases. …”
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    The histone demethylase PHF8 is a molecular safeguard of the IFNγ response
  4. 4444
    “…Issues of privacy and confidentiality were paramount. Participants preferred functionality that enables discreet connections to culturally competent health educators and treatment providers who can address the range of health and psychosocial concerns faced by BYMSM. …”
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    Technology Use and Preferences for Mobile Phone–Based HIV Prevention and Treatment Among Black Young Men Who Have Sex With Men: Exploratory Research
  5. 4445
    “…Meanwhile, the pore size of pATH was easily modulated by tuning the dimensions of the ZIF-8 polyhedrons. Of paramount importance was the fact that the dissolved ZIF-8 in solution was regenerated upon deprotonation of the ligand under mild alkali conditions, and was reused in the preparation of pATH, thus forming a delicate synthesis cycle. …”
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    Interfacial engineering of renewable metal organic framework derived honeycomb-like nanoporous aluminum hydroxide with tunable porosity
  6. 4446
    “…In the absence of screening programs for hearing loss in Saudi neonates, the family's role is of paramount importance. The aim of this study was to investigate the influence of geographic location on the course of identification, examination, and cochlear implantation in children in Saudi Arabia. …”
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    Cochlear implants in children: A cross-sectional investigation on the influence of geographic location in Saudi Arabia
  7. 4447
    por Jo, Danbi, Hyun, Hoon
    Publicado 2017
    “…Therefore, it is of paramount importance to develop targeted NIR fluorophores for unmet clinical needs. …”
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    Structure-Inherent Targeting of Near-Infrared Fluorophores for Image-Guided Surgery
  8. 4448
    “…Understanding spatio-temporal variability of trace elements fingerprints (TEF) in bivalve shells is paramount to determine the discrimination power of this analytical approach and secure traceability along supply chains. …”
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    Spatio-temporal variability of trace elements fingerprints in cockle (Cerastoderma edule) shells and its relevance for tracing geographic origin
  9. 4449
    por Asifa, Nazir, Farhath, Kanth
    Publicado 2017
    “…Hence, fungal cultures are of paramount importance in all suspected cases of onychomycosis because the antifungal agent with an appropriate spectrum of activity can only be used if the underlying fungal pathogen is identified correctly.…”
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    Current mycological profile of onychomycosis in Kashmir valley: A hospital-based study
  10. 4450
    “…Certain medications are more efficacious than others in managing these headache disorders, hence establishing the correct diagnosis is of paramount importance. CASE PRESENTATION: An 86-year-old female presented with chronic daily headache of 1 year duration. …”
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    Case report of hypnic headache: a rare headache disorder with nocturnal symptoms
  11. 4451
    “…Hence an understanding of disease mechanisms at the molecular level is of paramount importance for identifying possible intervention points for their control. …”
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    Pathogen recognition in compatible plant-microbe interactions
  12. 4452
    “…It is of paramount importance to improve the control over large area growth of high quality molybdenum disulfide (MoS(2)) and other types of 2D dichalcogenides. …”
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    Chelant Enhanced Solution Processing for Wafer Scale Synthesis of Transition Metal Dichalcogenide Thin Films
  13. 4453
    por Uwaezuoke, Samuel N
    Publicado 2017
    “…However, their validation using high-quality and large longitudinal studies is of paramount importance, as well as the subsequent development of a biomarker panel which can reliably predict and evaluate this renal microvascular disease. …”
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    The role of novel biomarkers in predicting diabetic nephropathy: a review
  14. 4454
    “…Species-specific adaptations in brain and behavior are paramount to survival and reproduction in diverse ecological niches and it is naive to think adult neurogenesis escaped these evolutionary pressures. …”
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    Solving the Neurogenesis Puzzle: Looking for Pieces Outside the Traditional Box
  15. 4455
    “…Detection of single-trial movement intentions from EEG is paramount for brain-computer interfacing in neurorehabilitation. …”
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    Classification of Hand Grasp Kinetics and Types Using Movement-Related Cortical Potentials and EEG Rhythms
  16. 4456
    “…The prevention, early diagnosis and adequate symptomatic treatment are of paramount importance. The fat embolism syndrome should always be considered in patients with Duchenne muscular dystrophy presenting with fractures, or an unexplained and sudden worsening of respiratory and cardiac symptoms.…”
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    Fat embolism after fractures in Duchenne muscular dystrophy: an underdiagnosed complication? A systematic review
  17. 4457
    “…Therefore, understanding and optimizing immunomodulation will be paramount for successful clinical xenotransplantation. …”
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    The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation
  18. 4458
    “…The knowledge of genetic polymorphisms associated with EH is of paramount importance because it leads to a better understanding of the etiology and pathophysiology of this pathology.…”
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    Relationship between ADD1 Gly460Trp gene polymorphism and essential hypertension in Madeira Island
  19. 4459
    “…Selection of implant device and optimal sizing is of paramount importance. The size of the delivery sheath (11 French in our patient) is a potential limitation for the GCSO in smaller infants.…”
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    Transcatheter atrial septal defect closure in an infant (body weight 6.4 kg) using the GORE CARDIOFORM septal occluder (GCSO)
  20. 4460
    “…Thus the need for alternative treatments is paramount. A BioArtificial Liver machine could temporarily replace the functions of the liver, buying time for the patient’s liver to repair and regenerate. …”
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    A clinical-scale BioArtificial Liver, developed for GMP, improved clinical parameters of liver function in porcine liver failure
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