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  1. 4541
    “…These results confirm that quantitative analysis of HFOs can boost presurgical evaluation and indicate the paramount importance of algorithm selection for clinical applications.…”
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    Assessing Epileptogenicity Using Phase-Locked High Frequency Oscillations: A Systematic Comparison of Methods
  2. 4542
    “…Therapeutically targeting receptor tyrosine kinases has proven to be paramount to overcoming chemotherapy resistance in several cancer indications, improving patient outcomes. …”
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    Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer
  3. 4543
    “…HCHO sensors are therefore of paramount importance for timely detection in daily life. …”
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    Ag Nanoparticles Sensitized In(2)O(3) Nanograin for the Ultrasensitive HCHO Detection at Room Temperature
  4. 4544
    “…Multidisciplinary approach in the management of oral and dental manifestations associated with ED including pediatric dentists, prosthodontists, and orthodontists is of paramount importance. HOW TO CITE THIS ARTICLE: Gholman RR, Kassar WM, et al. …”
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    Dental Rehabilitation of a Child with Ectodermal Dysplasia: A Case Report
  5. 4545
    “…Finally, using Gal-1 and Gal-3 as paramount examples, we review a series of recent advances in the development of engineered galectins and galectin inhibitors, aiming to dissect the structure-activity relationship through the description of their interaction at the molecular level.…”
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    The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design
  6. 4546
    “…The development of optical biosensors for the rapid and costless determination of clinical biomarkers is of paramount importance in medicine. Here we report a fast and low-cost biosensor based on a plasmonic D-shaped plastic optical fibre (POF) sensor derivatized with an aptamer specific for the recognition of thrombin, the target marker of blood homeostasis and coagulation cascade. …”
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    D-shaped plastic optical fibre aptasensor for fast thrombin detection in nanomolar range
  7. 4547
    “…These issues are of paramount importance to the development of optimal fMRI practices for educational applications.…”
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    Educational fMRI: From the Lab to the Classroom
  8. 4548
    “…BACKGROUND: Peer reviewed research is paramount to the advancement of science. Ideally, the peer review process is an unbiased, fair assessment of the scientific merit and credibility of a study; however, well-documented biases arise in all methods of peer review. …”
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    Unprofessional peer reviews disproportionately harm underrepresented groups in STEM
  9. 4549
    “…As early intervention with debridement in prosthetic joint infection (PJI) is paramount to retain the implant and to prevent infection relapse; eliminating PJI after SAB is important. …”
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    Staphylococcus aureus Bloodstream Infection in Patients With Prosthetic Joints in the Prospective VIRSTA Cohort Study: Frequency and Time of Occurrence of Periprosthetic Joint Infection
  10. 4550
    “…The steady oxidation state of Cu in an in situ condition is the paramount key and dominates the products’ profile of the CO(2)RR rather than other factors (e.g., crystal facets, atomic arrangements, morphology, elements) that have been investigated in numerous reports.…”
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    Quantitatively Unraveling the Redox Shuttle of Spontaneous Oxidation/Electroreduction of CuO(x) on Silver Nanowires Using in Situ X-ray Absorption Spectroscopy
  11. 4551
    “…The event can also occur intraoperatively and the preoperative control of IOP is of paramount importance in the prevention of ODR.…”
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    Intraoperative Ocular Decompression Retinopathy During 23 Gauge Transconjunctival Vitrectomy: A Case Report
  12. 4552
    “…Understanding and modeling the mobility of individuals is of paramount importance for public health. In particular, mobility characterization is key to predict the spatial and temporal diffusion of human-transmitted infections. …”
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    Are you getting sick? Predicting influenza-like symptoms using human mobility behaviors
  13. 4553
    “…Computation of error metrics is of paramount importance in approximate circuits to measure the degree of approximation. …”
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    Error metrics determination in functionally approximated circuits using SAT solvers
  14. 4554
    “…Pancreatic cancer (PC) is one of the most lethal, chemoresistant malignancies and it is of paramount importance to find more effective therapeutic agents. …”
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    The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer
  15. 4555
    “…One topic that is of paramount importance for both targeted and untargeted approaches is the availability of reference standards to identity and quantity the formed degradation products. …”
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    Novel analytical methods to study the fate of mycotoxins during thermal food processing
  16. 4556
    “…Long-term temporal genetic monitoring is paramount in determining future viability of cosmopolitan marine species, identifying genetic units for conservation management, and for understanding aggregation structure and dynamics.…”
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    Spatio-temporal genetic tagging of a cosmopolitan planktivorous shark provides insight to gene flow, temporal variation and site-specific re-encounters
  17. 4557
    “…Knowing the future consequences and adjusting toward the disease could be paramount for patients in facing uncertainty and they might feel that creating a relationship with physicians could be a secondary issue. …”
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    The clinical-care focused psychological interview (CLiC): a structured tool for the assessment of cancer patients’ needs
  18. 4558
    “…Although these studies are paramount for understanding species diversity, few of them actually formalize species delimitations to the final step of nomenclatural acts. …”
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    One step beyond a broad molecular phylogenetic analysis: Species delimitation of Adenomera marmorata Steindachner, 1867 (Anura: Leptodactylidae)
  19. 4559
    “…This study contributes to the body of knowledge on the toxicology of mixtures and gives one more evidence of the paramount importance of mixture toxicity studies, especially in assessing the endocrine disruptive effects of chemicals.…”
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    Toxic Effects of the Mixture of Phthalates and Bisphenol A—Subacute Oral Toxicity Study in Wistar Rats
  20. 4560
    “…Grafting bone substitute is paramount to prevent the alveolar ridge resorption after tooth extraction and facilitate the subsequent implant treatment. …”
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    The Injectable Woven Bone-Like Hydrogel to Perform Alveolar Ridge Preservation With Adapted Remodeling Performance After Tooth Extraction
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