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  1. 4781
    “…BACKGROUND: Prevention of dental caries is paramount in reducing the global burden of the disease. …”
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  2. 4782
    “…Furthermore, the anti-inflammatory potential of these cells has paramount importance in the treatment of sepsis. We need alternative therapeutic approaches to treat end-stage liver failure. …”
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  3. 4783
  4. 4784
  5. 4785
    “…Hence, attempts to discover safe and efficacious therapeutics and reliable biomarkers are of paramount importance. MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. …”
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  6. 4786
    “…Towards these directions and within the concept of circular (bio)economy, the development of efficient and sustainable catalytic processes is of paramount importance. Within this context, the design of novel catalysts play a key role, with carbon-based nanocatalysts (CnCs) representing one of the most promising class of materials. …”
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  7. 4787
    “…Moreover, to plan and follow interventions, better-quality data are paramount. For healthcare developments and improvement, neonates must be acknowledged as humans entitled to rights and freedoms, as stipulated by international law. …”
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  8. 4788
    “…In the context of digital health, it is of paramount importance to determine how a specific patients' population reflects into the healthcare dynamics of the hospital, to investigate how patients' sub-group/strata respond to the different care processes, in order to generate novel hypotheses regarding the most effective healthcare strategies. …”
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  9. 4789
    “…In addition, machine vision algorithms are developed to recognize human actions such as coughing and sneezing, which are paramount symptoms of respiratory infections. The proposed system is implemented and tested in outdoor environments. …”
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  10. 4790
    “…As both interest and development within this field continues to grow, however, there are challenges being identified that are paramount to further advancement. In reviewing both the literature and trajectory of the field, research priorities can be identified and utilised to facilitate fundamental research alongside whole systems evaluation. …”
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  11. 4791
    “…Relevant pathologic outcomes are paramount in evaluating preclinical models and therapeutic outcomes and require careful advance planning. …”
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  12. 4792
    “…Extensive preoperative planning with imaging, accurate intraoperative evaluation of the bone loss, and comprehensive understanding of all the implant options available for the bone loss are paramount to success.…”
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  13. 4793
  14. 4794
    “…Bull fertility is of paramount importance in bovine industry because semen from a single bull is used to breed several thousands of cows; however, so far, no reliable test is available for bull fertility prediction. …”
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  15. 4795
    “…Despite its paramount importance, the predominant association of early IgE production with harmless antigens, via germinal-center B- and T-cell subpopulations or extrafollicular activation, remains unresolved. …”
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  16. 4796
    “…Therefore, appropriate investigation of its specific etiology is paramount to provide adequate diagnosis, specific therapy and prevent its recurrence. …”
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  17. 4797
    “…Early prevention from accelerated neurocognitive declines with advanced aging and the delay of the onset of dementia have became paramount for the achievement of active aging. The present study examined whether the proposed non-pharmaceutical, multi-component exercise training which combined Tai-Chi exercise, Aerobic fitness, and thera-band therapy protects against age-related neurocognitive and physical deterioration in the older participants with amnestic mild cognitive impairment (aMCI). …”
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  18. 4798
    “…CONCLUSIONS: Sustaining effective and culturally informed suicide prevention efforts is of paramount importance to prevent suicide and save lives. …”
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  19. 4799
    “…Data on the morphology of the lake and its hydrological variations along time may be of paramount ecological importance for the managers of this natural space. …”
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  20. 4800
    “…Preserving function and independence of our aging population is paramount. A key component to maintaining independence is the preservation of cognitive function. …”
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