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  1. 5121
    “…Discerning the potential differences in the gut microbiota associated with muscle atrophy-related diseases, understanding their influence on disease development, and recognizing their potential as intervention targets are of paramount importance. This review aims to provide a comprehensive overview of the role of the gut microbiota in muscle atrophy-related diseases. …”
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  2. 5122
    “…Fundamental principles to prevent the spread of monkeypox, including maintaining personal hygiene and avoiding close contact with symptomatic patients, are of paramount importance.…”
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  3. 5123
    “…Developing accurate models for groundwater control is paramount for planning and managing life-sustaining resources (water) from aquifer reservoirs. …”
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  4. 5124
    “…Pathogenesis typically involves genetic alterations of the triple helix, a hallmark structural feature that bestows exceptional mechanical resistance to tensile forces and a capacity to bind a plethora of macromolecules. Yet, there is a paramount knowledge gap in understanding the functionality of distinct sites along the triple helix. …”
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  5. 5125
    “…Consequently, maintaining a functional balance between skeletal muscle and adipose tissue becomes paramount in regulating energy metabolism and promoting overall health. …”
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  6. 5126
    “…A high index of suspicion, awareness of the clinico-radiological presentations, and comprehensive genetic evaluation are paramount because treatment options are available for several disorders when diagnosed early in the disease course.…”
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  7. 5127
    “…In recent years, it has become clear that cancers are best understood if studied as ecosystems in which the impact of non-cancer-cell-autonomous events—dependent on complex interaction between the cancer and its environment, both local and systemic—plays a paramount role, probably as significant as the cell-autonomous alterations occurring in the cancer cell. …”
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  8. 5128
    “…The role of portal decompression such as transjugular intrahepatic portosystemic shunting can be considered in selected high-risk patients, but further prospective study of this approach is required. It is of paramount importance that patients are discussed in a multidisciplinary forum, and that patients are carefully counselled about potential risks and benefits.…”
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  9. 5129
    “…The work environment is paramount to ensuring good mental health. DISCLOSURE OF INTEREST: None Declared…”
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  10. 5130
    “…The best management modality for pain alleviation is of paramount importance. OBJECTIVES: This study aimed to evaluate the effect of intravenously administered morphine and oral tamsulosin compared to the independent use of morphine in patients with renal colic. …”
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  11. 5131
    “…However, the relative contribution of each on tumor-specific cytotoxicity is still unclear. It is paramount to understand these PAR-dependent mechanisms, given that resistance to PARPi is a challenge in the clinic. …”
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  12. 5132
    “…We also modeled the “regression dilution bias”, a typical overestimation of younger ages and underestimation of older ages, which correction is paramount for personalized brain age-based biomarkers. …”
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  13. 5133
    “…We concluded that Amazon River plume is a paramount physical feature that profoundly affects the dynamics of the mesoscale habitat structure in the Western Equatorial Atlantic Ocean and that such habitat structure is responsible for shaping planktonic cnidarian assemblages both in neritic and oceanic provinces.…”
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  14. 5134
    “…In the era of interconnected and intelligent cyber-physical systems, preserving privacy has become a paramount concern. This paper aims a groundbreaking proof-of-concept (PoC) design that leverages consortium blockchain technology to address privacy challenges in cyber-physical systems (CPSs). …”
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  15. 5135
    “…Evaluating the strength of the ankle muscles in older adults is of paramount importance. The purpose of this study was to formulate an equation to estimate ankle muscle strength by utilizing the basic physical characteristics of the subject and the variables related to their ability to perform the standing heel-rise test (SHRT). …”
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  16. 5136
    “…Therefore, it is of paramount significance to understand the factors governing the underlying complex processes in these structures. …”
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  17. 5137
    “…For KT to be successful, it is paramount for researchers to play an active role in encouraging evidence uptake and use in decision-making. …”
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  18. 5138
    “…Increasing policy-makers’ and clinicians’ awareness about the main factors influencing patients’ experience of loss of control is of paramount importance in order to develop skills and strategies able to address them, reinforcing patients’ empowerment, reducing their feeling of coercion and improving their well-being.…”
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  19. 5139
    “…Continuous staff education on handling sharp instruments, encouraging anonymous reporting, and up-to-date revisions of guidelines and policies are of paramount importance to lessen the burden of sharp injuries.…”
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  20. 5140
    “…CONCLUSIONS: It is possible to do the ophthalmological follow-up of 82% of the population with diabetes in primary health care, involving its professionals and team-working with the ophthalmologists. It is paramount to consider diabetic retinopathy within the global context of the person with diabetes, relating diabetic retinopathy with the other microvascular complications and cardiovascular diseases.…”
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