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  1. 5241
    “…A differential diagnosis from cholangiocarcinoma is of paramount importance and mainly relies on pathology.…”
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    Metastatic breast cancer mimicking a hilar cholangiocarcinoma: case report and review of the literature
  2. 5242
    “…Understanding the dynamic behavior of switchable surfaces is of paramount importance for the development of controllable and tailor-made surface materials. …”
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    Modulation of Biointeractions by Electrically Switchable Oligopeptide Surfaces: Structural Requirements and Mechanism
  3. 5243
    “…When using cell lines to study cancer, phenotypic similarity to the original tumor is paramount. Yet, little has been done to characterize how closely Merkel cell carcinoma (MCC) cell lines model native tumors. …”
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    Assessment of Cancer Cell Line Representativeness using Microarrays for Merkel Cell Carcinoma
  4. 5244
    “…INTRODUCTION: Local anesthesia has a paramount role in any branches of medical sciences specially dentistry. …”
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    Effect of a trial pharmaceutical solution on reversing sensations after using lidocain: An animal study
  5. 5245
    “…OBJECTIVE: Runt-related transcription factor 2 (RUNX2) and osterix (OSX) as two specific osteoblast transcription factors and distal-less homeobox 5 (DLX5) as a non-specific one are of paramount importance in regulating osteoblast related genes including osteocalcin, bone sialoprotein (BSP), osteopontin and collagen type Iα1. …”
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    Different Methylation Patterns of RUNX2, OSX, DLX5 and BSP in Osteoblastic Differentiation of Mesenchymal Stem Cells
  6. 5246
    “…Introduction: Preoperative characterisation of ovarian masses into benign or malignant is of paramount importance to optimise patient management. …”
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    Automated characterisation of ultrasound images of ovarian tumours: the diagnostic accuracy of a support vector machine and image processing with a local binary pattern operator
  7. 5247
    “…BACKGROUND AND OBJECTIVE: Patient satisfaction is of paramount importance when delivering a patient-centered service. …”
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    Patient satisfaction with radioiodine treatment and telephone follow-up for the management of thyrotoxicosis
  8. 5248
    “…Also present in LECA, PA200, PA28, and PI31 showed a more contrasted evolutionary picture, because many lineages have subsequently lost one or two of them. The paramount conservation of PA700 composition in all eukaryotes and the dynamic evolution of PA200, PA28, and PI31 are discussed in the light of current knowledge on their physiological roles.…”
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    Evolution of Proteasome Regulators in Eukaryotes
  9. 5249
    “…Point-of-care (POC) viral load measurement is of paramount importance with significant impact on a broad range of applications, including infectious disease diagnostics and treatment monitoring specifically in resource-constrained settings. …”
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    Printed Flexible Plastic Microchip for Viral Load Measurement through Quantitative Detection of Viruses in Plasma and Saliva
  10. 5250
    por Nemaura, Tafireyi
    Publicado 2015
    “…Understanding drug transportation mechanisms in the human body is of paramount importance in modeling Pharmacokinetic-Pharmacodynamic relationships. …”
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    Modeling transportation of efavirenz: inference on possibility of mixed modes of transportation and kinetic solubility
  11. 5251
    “…BACKGROUND AND OBJECTIVES: The diagnosis of early oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) is of paramount clinical importance given the mortality rate of late stage disease. …”
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    Techniques for early diagnosis of oral squamous cell carcinoma: Systematic review
  12. 5252
    “…Early medical evaluation of any postoperative nerve injury is of paramount importance.…”
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    Postoperative wristwatch-induced compressive neuropathy of the hand: a case report
  13. 5253
    “…The results of the proteomic analysis were of paramount importance to differentiate the defense mechanisms used by both progenies of T. cacao.…”
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    Molecular, Biochemical and Ultrastructural Changes Induced by Pb Toxicity in Seedlings of Theobroma cacao L.
  14. 5254
    “…The ability to adapt to increased water temperatures will be of paramount importance for many fish species as the climate continues to warm and water resources become limited. …”
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    Differential Expression of Genes that Control Respiration Contribute to Thermal Adaptation in Redband Trout (Oncorhynchus mykiss gairdneri)
  15. 5255
    “…BACKGROUND: Assessment of quality of life (QOL) is of paramount importance for improving postpartum QOL which will in turn enhance QOL of mothers, children, individuals, and the community. …”
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    A Comparison of Mothers’ Quality of Life after Normal Vaginal, Cesarean, and Water Birth Deliveries
  16. 5256
    “…The dominance of Asian female lineages is especially apparent in the X chromosome compared with the autosomes, suggesting that women played a paramount role during and after the period of Asian immigration into Timor, perhaps driven by the matrilocal marriage practices of expanding Austronesian communities.…”
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    Isolation, contact and social behavior shaped genetic diversity in West Timor
  17. 5257
    “…Cure rates for renal cell carcinoma are related to tumor grade and stage; therefore, diagnostic methods for early detection and new therapeutic modalities are of paramount importance. Epigenetics can be defined as inherited modifications in gene expression that are not encoded in the DNA sequence itself. …”
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    The role of epigenetics in kidney malignancies
  18. 5258
    “…Pre- and intraoperative diagnostic techniques facilitating tumor staging are of paramount importance in colorectal cancer surgery. …”
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    uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery
  19. 5259
    “…Optimizing the fixation environment is paramount. The purpose of this study was to compare two glenoid cementing techniques for fixation in total shoulder arthroplasty. …”
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    An in vitro study comparing limited to full cementation of polyethylene glenoid components
  20. 5260
    por Wicks, Paul, Chiauzzi, Emil
    Publicado 2015
    “…While a proper balance must be struck between innovation and caution, patient safety must be paramount. Please see related articles: http://dx.doi.org/10.1186/s12916-015-0444-y, http://www.biomedcentral.com/1741-7015/13/106 and http://www.biomedcentral.com/1741-7015/13/58…”
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    ‘Trust but verify’ – five approaches to ensure safe medical apps
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