“…Effective and sensitive communication with potential donors and their family/friends is paramount.…”
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“…Overall, we identify electrical signals as important contributors to the co-ordination and regulation of human T cell functions, paving the way for a new research area into effects of naturally occurring and clinically-applied EFs in conditions where control of T cell activity is paramount.…”
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“…As safety of volunteers in challenge studies is of paramount importance and treatment timing can affect primary outcomes, a standard for early antibiotic administration was established as follows: (1) when the primary endpoint is met; (2) if a fever of ≥39.0°C develops; or (3) if the study physician deems it appropriate. …”
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“…Careful correlation with imaging and clinico-pathologic studies is paramount to determining their origin and guiding further clinical treatment.…”
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“…Paucity of literature on pneumopericardium makes outlining any new case of paramount importance to emphasize the aspects of diagnosis and management of this rare condition. …”
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“…However, given the relatively high complication risk associated with ASD correction, it is of paramount importance to develop robust prognostic tools for predicting risk profile and outcomes. …”
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“…CONCLUSION: Analyzing CEJ in primary dentition is of paramount importance as it is a vulnerable zone in terms of caries progression and restorative margins. …”
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“…The results of the present study are of paramount importance for designing surveillance and control measures for brucellosis in camel populations.…”
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“…Mounting evidence has shown that lncRNAs have manifested a paramount function in the pathophysiology of human diseases, especially in the pathogenesis and progression of cancers. …”
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“…Measurement of the antioxidant potential using in vitro assays is paramount in the assessment of various food products and nutraceuticals. …”
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“…Therefore, the development of effective therapeutic strategies is of paramount importance. In this study, we investigated whether Miyako Island Bidens pilosa (MBP) can alleviate the neurological deterioration observed in a superoxide dismutase-1 G93A mutant transgenic mouse (G93A mouse) model of ALS. …”
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“…Maintenance of periodontal health is of paramount importance for successful implant therapy.…”
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“…Early diagnosis and prompt treatment is of paramount importance to avoid fatalities in acute infections.…”
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“…Therefore, knowledge of clinical characteristics and differential diagnosis of PLPH is paramount. Furthermore, if severe PLPH occurs, a consultation with a neurologist and imaging studies should be considered for a differential diagnosis of PLPH.…”
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“…CONCLUSION: Good knowledge and positive attitude are paramount for the effective implementation of the antibiotic stewardship program. …”
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“…OBJECTIVES: The need for proper wound closure is of paramount importance after any intra-oral surgery. …”
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“…Laser energy sealing systems have attracted much attention over the past decade given the general shift in surgical paradigm toward less invasive surgical approaches. Given this, it is paramount to have an objective method with which the quality of energy seals can be evaluated. …”
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“…Anti-receptor autoantibody pathologies are considered T cell-dependent, B-cell-mediated autoimmune disorders: the knowledge about the presence of circulating and/or localized autoantibodies to target organs and identification of autoantigens involved in the autoimmune reaction is of paramount importance. Due to the close correlation between the concentration of anti-receptor autoantibodies, the autoimmune target of some cell-surface receptors and the intensity of symptoms, the measurement of these immunoglobulins has become central to diagnose autoimmune diseases in all affected patients, not just in clinically dubious cases. …”
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“…ARDS can be caused by various aetiologies, and the adequate treatment of the responsible cause is crucial to improve the outcome. It is of paramount importance to characterize the mechanisms causing lung injury to optimize both the aetiological treatment and the symptomatic treatment. …”
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“…SUMMARY: Each current vaccine strategy has distinct advantages and disadvantages. Therefore, it is paramount that multiple strategies be advanced quickly and then evaluated for safety and efficacy. …”
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