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  1. 5621
    “…Studies such as ours are paramount to better understanding how environmental factors influence ecological and evolutionary aspects.…”
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    Classification and Characterization of the Manoor Valley’s (Lesser Himalaya) Vegetation from the Subtropical-Temperate Ecotonal Forests to the Alpine Pastures along Ecological Variables
  2. 5622
    “…BACKGROUND: Underweight is one of the paramount major worldwide health problems, and it traces a big number of populations from infancy to old age. …”
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    Trends and Determinants of Underweight among Children under Five Years in Ethiopia: Further Analysis with Ethiopian Demographic and Health Survey 2005–2016—Multivariate Decomposition Analysis
  3. 5623
    “…Sustaining SSP growth and innovation is paramount for preventing overdose deaths and HIV/HCV outbreaks after the deadliest year of the opioid epidemic in 2020.…”
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    Harm reduction and health services provided by syringe services programs in 2019 and subsequent impact of COVID-19 on services in 2020()
  4. 5624
    “…Since aneurysm rupture leading to subarachnoid hemorrhage is a devastating medical emergency with high mortality, the ability to noninvasively diagnose high‐risk aneurysms is of paramount importance. Moreover, treatment of unruptured aneurysms with invasive surgery or minimally invasive neurointerventional surgery poses relatively high risk and there is presently no medical treatment of aneurysms. …”
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    Biophysical targeting of high‐risk cerebral aneurysms
  5. 5625
    “…In this scenario, surveillance of the vaccine in the real world becomes even more paramount. This responsibility falls to observational researchers who can provide an essential safety net by continuing to monitor the effectiveness and safety of a COVID-19 vaccine after licensing. …”
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    Postmarketing studies: can they provide a safety net for COVID-19 vaccines in the UK?
  6. 5626
    “…BACKGROUND: The identification of novel biomarkers for the early detection and monitoring of gastric (GC) and colorectal cancer (CRC) is of paramount importance. TM9SF4 is a newly described V-ATPase interacting protein involved in the malignant progression of cancer cells. …”
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    TM9SF4 expression in tumor tissues: a novel diagnostic biomarker for gastrointestinal tumors
  7. 5627
    “…The EHRA guidelines update also introduce some interesting changes in drug–drug interaction patterns with the reduction of the level of the interaction with dexamethasone, which is of paramount importance in this clinical context. Considering the new information, the protocol, named ANIBAL II, has been updated. …”
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    Dabigatran in patients with atrial fibrillation after COVID-19 hospitalization: an update of the ANIBAL protocol
  8. 5628
    “…Understanding the location-based characteristics and spatial patterns of socioeconomic and health factors linked to COVID-19 deaths is paramount for policy designing and decision making. …”
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    Ranking the importance of demographic, socioeconomic, and underlying health factors on US COVID-19 deaths: A geographical random forest approach
  9. 5629
    “…Characterizing melanins in situ and determining their 3D z-epidermal distribution is paramount for understanding physiological/pathological processes of melanin neosynthesis, transfer, degradation or modulation with external UV exposure or cosmetic/pharmaceutical products. …”
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    In vivo melanin 3D quantification and z-epidermal distribution by multiphoton FLIM, phasor and Pseudo-FLIM analyses
  10. 5630
    “…Twin studies have been of paramount importance to comprehend the immunogenetics of infectious diseases. …”
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    Recurrence of COVID-19 associated with reduced T-cell responses in a monozygotic twin pair
  11. 5631
    “…Understanding various mechanisms which affect on such species behaviors can be possible by evolutionary games, and in particular, the rock–paper–scissors (RPS) game has been played a key role as a paradigmatic model to explore biodiversity from microbiota to societies. Among paramount mechanisms in systems of RPS, the role of intraspecific interaction has been recently noted in terms of promoting biodiversity. …”
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    The effect of territorial awareness in a three-species cyclic predator–prey model
  12. 5632
    “…DISCUSSION/SIGNIFICANCE OF IMPACT: Because a primary foci of COBRE grant mechanisms is the development of junior level investigators, evaluating their skills, mentoring experiences, and the usefulness of services is paramount to the sustainability and collaborative research environments of COBREs. …”
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    4014 Results of a Formative Evaluation of the Cardiopulmonary Vascular Biology (CPVB) Center of Biomedical Research Excellence (COBRE)
  13. 5633
    por Brown, Kate, Capili, Bernadette
    Publicado 2020
    “…RESULTS/ANTICIPATED RESULTS: Understanding the life of an individual with a cocaine use disorder is paramount to successful recruitment and retention in addiction research studies. …”
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    4131 Recruitment and Retention of Individuals with a Cocaine Use Disorder
  14. 5634
    “…Looking at the uncertainty of the current scenario, it is difficult to predict how long online classes will have to continue. Hence, it is of paramount importance that we assess the effectiveness of online classes and consequently take measures to ensure proper delivery of content to students, especially in a skilled field like medicine, so we concluded that face-to-face learning is of utmost importance in medical institutions.…”
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    Online classes versus traditional classes? Comparison during COVID-19
  15. 5635
    “…BACKGROUND: The relative anatomical understanding of the perirectal fasciae is of paramount importance for the proper performance of total mesorectal excision (TME). …”
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    Anatomy of the perirectal fascia at the level of rectosacral fascia revisited
  16. 5636
    “…EBTB bronchoscopic characterization is paramount to ensure correct diagnosis, immediate treatment and to prevent complication.…”
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    Bronchoscopic Features and Morphology of Endobronchial Tuberculosis: A Malaysian Tertiary Hospital Experience
  17. 5637
    “…Although responses are observed, they are often short-lived, thus making in-depth characterization of the mechanisms of resistance of paramount importance. METHODS: Here, we present a rapid-autopsy case of a patient who had a KRAS(G12C)-mutant lung adenocarcinoma who initially responded to a KRAS G12C inhibitor but then rapidly developed resistance. …”
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    Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition
  18. 5638
    “…Canines are paramount teeth for esthetics and function. Transmigration of the lower permanent canine is a rare process of alteration of the eruption path toward the opposite part of the mandible. …”
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    A rare case of transmigrated mandibular canine and combined orthodontic–surgical management
  19. 5639
    “…This includes having a computer or a laptop for schoolwork, having someone to help with schoolwork if the child is worried about falling behind, and having schoolwork checked by a teacher. This points to the paramount importance of adequate digital technologies in the home as well as the availability of help during periods of remote schooling.…”
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    Learning in a Pandemic: Primary School children’s Emotional Engagement with Remote Schooling during the spring 2020 Covid-19 Lockdown in Ireland
  20. 5640
    “…Endoscopic evaluation to reliably grade disease activity, detect complications including cancer and verification of mucosal healing are paramount in the care of patients with ulcerative colitis (UC); but this evaluation is hampered by substantial intra- and interobserver variability. …”
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    Artificial intelligence enabled automated diagnosis and grading of ulcerative colitis endoscopy images
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