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  1. 6801
    “…Most of the miRNA targets are transcription factors (TFs) which have paramount importance in regulating the plant growth and development. …”
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    MicroRNA and Transcription Factor: Key Players in Plant Regulatory Network
  2. 6802
    “…BACKGROUND: The development of cellular therapies to treat muscle wastage with disease or age is paramount. Resident muscle satellite cells are not currently regarded as a viable cell source due to their limited migration and growth capability ex vivo. …”
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    Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo
  3. 6803
    “…However, longitudinal studies emphasize the paramount importance of early symptom improvement for the course of disease in major depressive disorder (MDD). …”
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    Default mode network deactivation during emotion processing predicts early antidepressant response
  4. 6804
    “…In vivo accuracy of SEEG electrode positioning is of paramount importance since higher accuracy may lead to more precise resective surgery, better seizure outcome and reduction of complications. …”
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    Methodology, outcome, safety and in vivo accuracy in traditional frame-based stereoelectroencephalography
  5. 6805
    “…Safety assessments of GM crops are of paramount importance in research at developmental stages and before releasing transgenic plants into the marketplace. …”
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    A bioinformatics approach for identifying transgene insertion sites using whole genome sequencing data
  6. 6806
    “…Improved access to water supply along with environmental health intervention programs designed to promote good hygiene behavior could be of paramount importance to alleviate burden of childhood diarrhea. …”
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    Factors associated with diarrheal morbidity among under-five children in Jigjiga town, Somali Regional State, eastern Ethiopia: a cross-sectional study
  7. 6807
    “…Timely information about the spread of the disease was paramount to public health bodies issuing travel advisories. …”
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    Early detection of perceived risk among users of a UK travel health website compared with internet search activity and media coverage during the 2015–2016 Zika virus outbreak: an observational study
  8. 6808
    “…Early recognition and adequate management are of paramount importance.…”
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    Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
  9. 6809
    “…Understanding the factors that induce myofibroblastic differentiation is paramount to prevent or reverse the fibrogenic process. …”
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    Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases
  10. 6810
    “…Proper intervention and effective management is of paramount importance for the control and prognosis of paediatric asthma. …”
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    Paediatric asthma control under a community management model in China: a protocol for a prospective multicentre cohort study
  11. 6811
    “…As a consequence, continued exploration of novel targets is paramount to identify novel antivirals that do not suffer from cross-resistance with existing drugs. …”
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    Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import
  12. 6812
    “…Noticeably, the HIV-1 and SIV(mac239) EnvCDs were described to trigger nuclear translocation of NF-κB (Postler, Cell Host Microbes 2012). Given the paramount importance of identifying viral and host factors regulating HIV transcription, cellular signaling pathways and latency, and given that viral replication capacity is dependent on Env, we asked whether HIV EnvCDs from different HIV-1 subtypes differently modulated NF-κB. …”
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    Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation
  13. 6813
    “…BACKGROUND: Providing sufficient oxygenation and ventilation is of paramount importance for the survival of emergency patients. …”
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    Advanced airway management in hoist and longline operations in mountain HEMS – considerations in austere environments: a narrative review This review is endorsed by the International Commission for Mountain Emergency Medicine (ICAR MEDCOM)
  14. 6814
    “…CONCLUSION: CHWs, ANC and medical insurance are perceived to be important facilitators of BP/CR. Respectful care is paramount for improved maternal health. There is a need for addressing inconsistent health policies hindering the intention to access professional care.…”
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    Facilitators and barriers to birth preparedness and complication readiness in rural Rwanda among community health workers and community members: a qualitative study
  15. 6815
    “…Collaboration with Ministries of Health for support with enforcing national guidelines, and procuring supplies is paramount to a successful CrAg screening program. Development of a CrAg screening and treatment program within the HIV clinic infrastructure has a number of barriers. …”
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    A qualitative evaluation of an implementation study for cryptococcal antigen screening and treatment in Uganda
  16. 6816
    “…Thus, characterization of the underlying DNA methyltransferases in genetically tractable bacteria is of paramount importance. Here, we characterized the methylome and orphan methyltransferases in the model cyanobacterium Synechocystis sp. …”
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    Identification of the DNA methyltransferases establishing the methylome of the cyanobacterium Synechocystis sp. PCC 6803
  17. 6817
    “…Efficient chromophore supply is paramount for the continuous function of vertebrate cone photoreceptors. …”
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    Examining the Role of Cone-expressed RPE65 in Mouse Cone Function
  18. 6818
    “…Although causation is not implied, careful patient selection is paramount to balance treatment-related toxicity risks with theoretical outcome benefits.…”
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    Postoperative chemoradiotherapy versus radiotherapy alone for elderly cervical cancer patients with positive margins, lymph nodes, or parametrial invasion
  19. 6819
    “…Therefore, assessing the proportion of death and associated factors among preterm neonates has a paramount importance in designing an effective strategy to intervene and achieve sustainable development goal. …”
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    Proportion and factors of death among preterm neonates admitted in University of Gondar comprehensive specialized hospital neonatal intensive care unit, Northwest Ethiopia
  20. 6820
    “…As such, these results are paramount for counseling, clinical management, and stratification in clinical research. …”
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    Facioscapulohumeral Dystrophy in Childhood: A Nationwide Natural History Study
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