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  1. 8461
    “…Subjective measures provide more information regarding individual training load, as heart rate measures alone do not account for collisions, eccentric muscle actions, muscle soreness, weather conditions, or accumulated training loads, which are paramount to the athlete experience. However, the current subjective metric for interpreting session training load (sRPE) is poorly shaped to the athlete's global response to the whole session, often showing poorer correlations to heart rate (HR) measures during intermittent or high-intensity activity. …”
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  2. 8462
  3. 8463
  4. 8464
    “…Although genetic defects are pivotal, cellular context is paramount. When it concerns tumor heterogeneity, perhaps we need to revisit the conventional wisdom of precision medicine and revise our current practice of targeted therapy in cancer care.…”
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  5. 8465
    “…Prevention of nosocomial SARS-CoV-2 infection of patients and staff was a paramount goal. Pediatric hospitals worldwide discontinued elective treatments and established a centralized admission process. …”
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  6. 8466
    por Chen, Jiahui, Wang, Rui, Wei, Guo-Wei
    Publicado 2021
    “…The mechanism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution and transmission is elusive and its understanding, a prerequisite to forecast emerging variants, is of paramount importance. SARS-CoV-2 evolution is driven by the mechanisms at molecular and organism scales and regulated by the transmission pathways at the population scale. …”
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  7. 8467
  8. 8468
    por Cunha, Eugénia
    Publicado 2021
    “…However, more research about how the skeletal system ages, a paramount question, is needed. While growth and development are programmed strictly by evolution and genetics, the same does not apply to adult degeneration process. …”
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  9. 8469
    “…Continuous refinement of these first-of-their kind estimates and confirmation of country willingness and ability to pay will be paramount to inform the decisions of policy makers and developers in relation to a leishmaniasis vaccine. …”
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  10. 8470
    “…Potential approaches are the daily intake of acetylsalicylic acid (ASA), shunting arachidonic acid into the lipoxygenase pathway, and a subsequent habituation to this constant inflammatory stimulus. Alternatively, the paramount interleukins 4 and 13 may be antagonized by the monoclonal antibody dupilumab. …”
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  11. 8471
    “…A thorough understanding of the mechanisms supporting p73 functional diversity is of paramount importance for the efficient and precise p73 targeting not only in cancer, but also in other pathological conditions where TP73 dysregulation is causally involved.…”
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  12. 8472
    “…Discovering and understanding the key characteristics of optimal photoelectrode materials is paramount to the realization of PEC technologies. Oxide-based photoelectrodes can satisfy many of these materials requirements, including stability in aqueous environments, band edges with reasonable alignment with the redox potentials for water splitting, and ease of synthesis. …”
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  13. 8473
    “…Parkinson’s disease (PD) is an acute and progressive neurodegenerative disorder, and diagnosis of the disease at its earliest stage is of paramount importance to improve the life expectancy of patients. …”
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  14. 8474
    “…Studying these exposure-related effects is of paramount importance for predicting how they respond to insecticide exposure and whether this exposure makes them more or less likely to transmit pathogens. …”
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  15. 8475
    “…Given the portability, cost-effectiveness and high time-resolution of EEG as compared to fMRI and other neuroimaging modalities, an efficient method of estimating an individual’s workload using EEG is of paramount importance. Multiple cognitive, psychiatric and behavioral phenotypes have already been known to be linked with “functional connectivity”, i.e., correlations between different brain regions. …”
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  16. 8476
  17. 8477
    “…Comfort of the critically unwell pediatric patient is paramount to ensuring good outcomes. Analgesia-based, multimodal sedative approaches are the foundation for comfort, whereby pain is addressed first and then sedation titrated to a predefined target based on the goals of care. …”
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  18. 8478
    “…CONCLUSION: The COVID-19-related nationwide lockdown has deprived retinoblastoma patients of optimal and timely management, leading to prolonged treatment interruptions, delays, permanent default, and death. It is of paramount importance for all the stakeholders to increase awareness, make necessary travel and logistic arrangements, and ensure continuity of care for children with retinoblastoma.…”
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  19. 8479
    “…[Image: see text] Reliable, label-free, and ultraselective detection of Pb(2+) and Ag(+) ions is of paramount importance for toxicology assessment, human health, and environmental protection. …”
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  20. 8480
    “…Accuracy and reproducibility in placing the implant on the mechanical axis has been shown to be paramount in all joint arthroplasty including total ankle replacement. …”
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