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  1. 8581
    “…Animal experimentation is of paramount importance in the progress of research, but it is becoming more evident that it has several limitations due to the numerous differences between animal tissues and real, in vivo human tissues. 3D bioprinting techniques have become an attractive tool for many basic and applied research fields. …”
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  2. 8582
    “…IMPACT AND IMPLICATIONS: Understanding factors counteracting HDV infections is paramount to develop curative therapies. We compared the responsiveness of three different cloned HDV strains to pegylated interferon alpha in chronically infected mice. …”
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  3. 8583
    “…CONCLUSION: Oxygen therapy is associated with poor survival in pwCF with and without LTx; harmonization of CF care throughout European countries and minimization of the onset of pulmonary gas exchange abnormalities using all available means remains of paramount importance.…”
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  4. 8584
    “…Communication and provision of documents are thus paramount. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13756-023-01228-w.…”
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  5. 8585
    “…Based on our findings, we believe it is paramount to evaluate the challenges faced by Fimea and how it could improve its performance. …”
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  6. 8586
    “…BACKGROUND: Health systems are complex, consisting of multiple interacting structures and actors whose effective coordination is paramount to enhancing health system goals. Health sector coordination is a potential source of inefficiency in the health sector. …”
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  7. 8587
    “…The stagnation in vaccine uptake during the height of the pandemic presented policy makers with a challenge that remains unresolved and is paramount for future pandemics and other crises: How to convince the (often not insubstantial) unvaccinated proportion of the population of the benefits of a vaccination? …”
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  8. 8588
    “…In this regard, a strong commitment by European and national professional societies to educate and inform practitioners, patients and carers is paramount. CLINICAL RELEVANCE STATEMENT: According to this survey expectations of patients and carers, and skepticism among professionals about the limited benefits of CS are the most important obstacles to the application of a no-shielding policy. …”
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  9. 8589
    “…An understanding of stakeholders’ views is paramount to the effective development and implementation of a trauma system inclusive of rural communities. …”
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  10. 8590
  11. 8591
    “…Solar cell’s precise modelling and estimation of its parameters are of paramount importance for the simulation, design, and control of PV system to achieve optimal performances. …”
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  12. 8592
  13. 8593
    “…VEHs endorsed trusting, long-term relationships with CTRS staff as paramount for facilitating access to services. Though CTRS addressed basic priorities (food, shelter, etc.) that traditionally compete with access to healthcare, some VEHs needed on-site healthcare services, at their tents, to access care. …”
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  14. 8594
  15. 8595
    “…Identification and preservation of the tumor-brain interface are of paramount importance. GCTs other than teratomas are treated with neoadjuvant chemotherapy and may eliminate the need for craniotomy. …”
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  16. 8596
  17. 8597
  18. 8598
  19. 8599
  20. 8600
    “…Timely identification and treatment of the underlying infection are paramount, along with effective control of systemic factors that may contribute to secondary brain injury. …”
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