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  1. 8601
    por Balay-Dustrude, Erin, Shenoi, Susan
    Publicado 2023
    “…Accurate assessment and measurement of the clinical, functional, and quality of life outcomes of patients with JIA are paramount for understanding the disease course and formulating effective treatment strategies. …”
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    Current Validated Clinical and Patient Reported Disease Outcome Measures in Juvenile Idiopathic Arthritis
  2. 8602
    “…In the future, if the healthcare system is asked to respond to another pandemic or similar situation, expediting time to OR to eliminate unnecessary time in the hospital and non-critical admissions should be paramount. LEVEL OF EVIDENCE: Level III, prognostic/epidemiological.…”
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    Prioritizing rapid COVID-19 testing in emergency general surgery patients decreases burden of inpatient hospital admission
  3. 8603
    “…CONCLUSIONS: Collaborative efforts between medical and dental professionals are paramount in comprehensively evaluating and treating patients with intricate complications from rare diseases. …”
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    Ligneous periodontitis exacerbated by Behçet’s disease in a patient with plasminogen deficiency and a stop-gained variant PLG c.1468C > T: a case report
  4. 8604
    “…Interventions to tackle this stigma can incorporate messages about HPV infections and latency to lessen the focus on the influence of sexual behavior on HPV acquisition, and instead, promote screening and treatment as paramount preventative measures.…”
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    “Easy women get it”: pre-existing stigma associated with HPV and cervical cancer in a low-resource setting prior to implementation of an HPV screen-and-treat program
  5. 8605
    “…Efforts to capture underscreened women are considerable and once women agree to participate, the provision of longitudinal validity of the screening test is of paramount relevance. We evaluate the addition of high risk HPV test (HPV) to cervical cytology as a primary screening test among underscreened women in the longitudinal prediction of intraepithelial lesions grade 2 or worse (CIN2+). …”
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    Protecting the underscreened women in developed countries: the value of HPV test
  6. 8606
    “…BACKGROUND: Accurate surveillance data are paramount to effective TB control. The Republic of South Africa’s National TB Control Program (NTP) has conducted TB surveillance since 1995 and adopted the Electronic TB Register (ETR) in 2005. …”
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    Completeness and Reliability of the Republic of South Africa National Tuberculosis (TB) Surveillance System
  7. 8607
    “…To identify the most effective treatment for CVD, it is paramount to understand the mechanism behind cardioprotective therapies. …”
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    Metformin improves the angiogenic potential of human CD34(+) cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction
  8. 8608
    “…BACKGROUND: The PD-1/PD-L1 axis plays a paramount role in the immune escape of tumor cells by negative regulation of T-cell functions. …”
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    Prognostic implications of PD-L1 expression in patients with soft tissue sarcoma
  9. 8609
    “…BACKGROUND: In order to evaluate the newly implemented gender-neutral HPV vaccination program, knowledge on the pre-vaccine prevalence of HPV infection is of paramount importance. Data on HPV infection among the women with no known previous cytological abnormalities are inexistent in Austria. …”
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    Pre-vaccine era cervical human papillomavirus infection among screening population of women in west Austria
  10. 8610
    “…A high index of suspicion and detailed understanding of abdominal compartment mechanics are paramount for the timely diagnosis of abdominal compartment syndrome in these patients. …”
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    Abdominal intra-compartment syndrome – a non-hydraulic model of abdominal compartment syndrome due to post-hepatectomy hemorrhage in a man with a localized frozen abdomen due to extensive adhesions: a case report
  11. 8611
    “…The identification of therapy-responsive and prognostic biomarkers is paramount important to stratify patients and guide therapies in clinical oncology and personalized medicine. …”
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    SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer
  12. 8612
    “…PURPOSE: The homeostasis of intracranial pressure (ICP) is of paramount importance for maintaining normal brain function. …”
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    Acute pressure changes in the brain are correlated with MR elastography stiffness measurements: initial feasibility in an in vivo large animal model
  13. 8613
    “…Consequently, effective and safe anticoagulation is paramount. Edoxaban is a direct oral anticoagulant (DOAC) approved VTE treatment. …”
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    Design and rationale of the non-interventional, edoxaban treatment in routiNe clinical prActice in patients with venous ThromboEmbolism in Europe (ETNA-VTE-Europe) study
  14. 8614
    “…Development of phytochemicals such as nimbolide that target the complex interaction between proteins and ncRNAs that regulate the autophagy/apoptosis flux is of paramount importance in cancer prevention and therapeutics.…”
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    Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer
  15. 8615
    “…An evaluation of the immunization of these children may be of paramount importance to implement timely measures aimed at preventing measles transmission. …”
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    Seroprevalence of measles vaccine antibody response in vertically HIV-infected children, in Morocco
  16. 8616
    “…This first-of-its-kind meta-analysis at IPD level of interaction of disease duration with the response to biologics in UC and CD may elucidate the impact of early initiation of biologics, which is of paramount importance for clinical practice and management strategies of inflammatory bowel disease. …”
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    Efficacy of biological drugs in short-duration versus long-duration inflammatory bowel disease: a protocol for a systematic review and an individual-patient level meta-analysis of randomised controlled trials
  17. 8617
    “…CONCLUSIONS: Understanding the operational complexities associated with running adaptive platform protocols is paramount for their conduct, adaptive platform trials offer an efficient model to run randomised controlled trials and we are continuing to work to reduce further the effort required from an operational perspective. …”
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    This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols
  18. 8618
    por Sartelli, Massimo, Abu-Zidan, Fikri M., Labricciosa, Francesco M., Kluger, Yoram, Coccolini, Federico, Ansaloni, Luca, Leppäniemi, Ari, Kirkpatrick, Andrew W., Tolonen, Matti, Tranà, Cristian, Regimbeau, Jean-Marc, Hardcastle, Timothy, Koshy, Renol M., Abbas, Ashraf, Aday, Ulaş, Adesunkanmi, A. R. K., Ajibade, Adesina, Akhmeteli, Lali, Akın, Emrah, Akkapulu, Nezih, Alotaibi, Alhenouf, Altintoprak, Fatih, Anyfantakis, Dimitrios, Atanasov, Boyko, Augustin, Goran, Azevedo, Constança, Bala, Miklosh, Balalis, Dimitrios, Baraket, Oussama, Baral, Suman, Barkai, Or, Beltran, Marcelo, Bini, Roberto, Bouliaris, Konstantinos, Caballero, Ana B., Calu, Valentin, Catani, Marco, Ceresoli, Marco, Charalampakis, Vasileios, Jusoh, Asri Che, Chiarugi, Massimo, Cillara, Nicola, Cuesta, Raquel Cobos, Cobuccio, Luigi, Cocorullo, Gianfranco, Colak, Elif, Conti, Luigi, Cui, Yunfeng, De Simone, Belinda, Delibegovic, Samir, Demetrashvili, Zaza, Demetriades, Demetrios, Dimova, Ana, Dogjani, Agron, Enani, Mushira, Farina, Federica, Ferrara, Francesco, Foghetti, Domitilla, Fontana, Tommaso, Fraga, Gustavo P., Gachabayov, Mahir, Gérard, Grelpois, Ghnnam, Wagih, Maurel, Teresa Giménez, Gkiokas, Georgios, Gomes, Carlos A., Guner, Ali, Gupta, Sanjay, Hecker, Andreas, Hirano, Elcio S., Hodonou, Adrien, Hutan, Martin, Ilaschuk, Igor, Ioannidis, Orestis, Isik, Arda, Ivakhov, Georgy, Jain, Sumita, Jokubauskas, Mantas, Karamarkovic, Aleksandar, Kaushik, Robin, Kenig, Jakub, Khokha, Vladimir, Khokha, Denis, Kim, Jae Il, Kong, Victor, Korkolis, Dimitris, Kruger, Vitor F., Kshirsagar, Ashok, Simões, Romeo Lages, Lanaia, Andrea, Lasithiotakis, Konstantinos, Leão, Pedro, Arellano, Miguel León, Listle, Holger, Litvin, Andrey, Lizarazu Pérez, Aintzane, Lopez-Tomassetti Fernandez, Eudaldo, Lostoridis, Eftychios, Luppi, Davide, Machain V, Gustavo M., Major, Piotr, Manatakis, Dimitrios, Reitz, Marianne Marchini, Marinis, Athanasios, Marrelli, Daniele, Martínez-Pérez, Aleix, Marwah, Sanjay, McFarlane, Michael, Mesic, Mirza, Mesina, Cristian, Michalopoulos, Nickos, Misiakos, Evangelos, Moreira, Felipe Gonçalves, Mouaqit, Ouadii, Muhtaroglu, Ali, Naidoo, Noel, Negoi, Ionut, Nikitina, Zane, Nikolopoulos, Ioannis, Nita, Gabriela-Elisa, Occhionorelli, Savino, Olaoye, Iyiade, Ordoñez, Carlos A., Ozkan, Zeynep, Pal, Ajay, Palini, Gian M., Papageorgiou, Kyriaki, Papagoras, Dimitris, Pata, Francesco, Pędziwiatr, Michał, Pereira, Jorge, Pereira Junior, Gerson A., Perrone, Gennaro, Pintar, Tadeja, Pisarska, Magdalena, Plehutsa, Oleksandr, Podda, Mauro, Poillucci, Gaetano, Quiodettis, Martha, Rahim, Tuba, Rios-Cruz, Daniel, Rodrigues, Gabriel, Rozov, Dmytry, Sakakushev, Boris, Sall, Ibrahima, Sazhin, Alexander, Semião, Miguel, Sharda, Taanya, Shelat, Vishal, Sinibaldi, Giovanni, Skicko, Dmitrijs, Skrovina, Matej, Stamatiou, Dimitrios, Stella, Marco, Strzałka, Marcin, Sydorchuk, Ruslan, Teixeira Gonsaga, Ricardo A., Tochie, Joel Noutakdie, Tomadze, Gia, Ugoletti, Lara, Ulrych, Jan, Ümarik, Toomas, Uzunoglu, Mustafa Y., Vasilescu, Alin, Vaz, Osborne, Vereczkei, Andras, Vlad, Nutu, Walędziak, Maciej, Yahya, Ali I., Yalkin, Omer, Yilmaz, Tonguç U., Ünal, Ali Ekrem, Yuan, Kuo-Ching, Zachariah, Sanoop K., Žilinskas, Justas, Zizzo, Maurizio, Pattonieri, Vittoria, Baiocchi, Gian Luca, Catena, Fausto
    Publicado 2019
    “…Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. …”
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    Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study
  19. 8619
    “…Parameters such as pathogen dose and inoculation route are paramount in animal models when studying disease pathogenesis. …”
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    Effects of challenge dose and inoculation route of the virulent Neospora caninum Nc-Spain7 isolate in pregnant cattle at mid-gestation
  20. 8620
    “…AIM: Urinary flow after urethroplasty is of paramount importance. The aim of this study is to evaluate the progression of uroflowmetry (UF) parameters after different distal and proximal hypospadias repair techniques. …”
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    Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
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