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  1. 8641
    “…Adherence to lung cancer screening is paramount to realize the mortality benefit, and reported adherence rates vary widely. …”
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    Patient motivations for non-adherence to lung cancer screening in a military population
  2. 8642
    “…Consequently, solving ancestral genome inference problems constitutes a task of paramount importance that continues to challenge the current methods used in this area, whose difficulty is further increased by the ongoing rapid accumulation of whole-genome data. …”
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    Achieving large and distant ancestral genome inference by using an improved discrete quantum-behaved particle swarm optimization algorithm
  3. 8643
    “…With increasing number of algorithms being proposed, effectively comparing them with state-of-the-art algorithms is paramount. These comparisons are usually performed using real data, without a known ground-truth, thus limiting the assessments. …”
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    G-Tric: generating three-way synthetic datasets with triclustering solutions
  4. 8644
    “…Hence, the establishment of an ethnicity-based BRCA1/2 variant database of the Chinese population is of paramount importance. In this study, panel-based sequencing served to detect BRCA1/2 variants in a Chinese multicenter cohort of 21,216 BC patients and 6434 healthy controls. …”
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    Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort
  5. 8645
    “…In addition, the treatment gap for these possible patients is large. It is therefore of paramount importance to develop therapeutic strategies with the aim of tackling this physically and mentally disabling disorder. …”
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    Prevalence of substance use disorders in an urban and a rural area in Suriname
  6. 8646
    “…In conclusion, this study identified culture-specific shortfalls in handwashing and unsafe food handling practices during COVID-19 in the Arab countries and sheds light on the paramount role of coordinated efforts between the local health authorities and the food safety and public health stakeholders in risk communication. …”
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    An on-line survey of the behavioral changes in Lebanon, Jordan and Tunisia during the COVID-19 pandemic related to food shopping, food handling, and hygienic practices
  7. 8647
    “…Public health authorities have been paramount in guaranteeing that adequate fresh air ventilation is promoted in classrooms to avoid SARS-CoV-2 transmission in educational environments. …”
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    Assessment of CO(2) and aerosol (PM(2.5), PM(10), UFP) concentrations during the reopening of schools in the COVID-19 pandemic: The case of a metropolitan area in Central-Southern Spain
  8. 8648
    “…As research in this area is scarce, the results generated by this study may become of paramount importance in improving the care of children receiving in-hospital CPR, in the era of increasing communication technology. …”
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    Impact of a shared decision-making mHealth tool on caregivers’ team situational awareness, communication effectiveness, and performance during pediatric cardiopulmonary resuscitation: study protocol of a cluster randomized controlled trial
  9. 8649
    “…Improving the supply of hypertensive medications is also paramount for better medication adherence.…”
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    The Role of Health Care Quality in Hypertension Self-Management: A Qualitative Study of the Experience of Patients in a Public Hospital, North-West Ethiopia
  10. 8650
    “…Nonetheless, AF is known to be the manifestation of a complex interaction between electrical and structural abnormalities and therefore, true electro-anatomical-structural imaging may elucidate important key factors of AF development, progression, and treatment. Therefore, it is paramount to identify which clinical questions could be successfully addressed by ECGI when it comes to AF characterization and treatment, and which questions may be beyond its technical limitations. …”
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    Electrocardiographic Imaging for Atrial Fibrillation: A Perspective From Computer Models and Animal Experiments to Clinical Value
  11. 8651
    “…CONCLUSIONS: Our data show the value of correlating clinical, epidemiological and genomic information for the understanding of viral evolution and its spatial distribution over time. This is of paramount importance to better inform policy making strategies to fight COVID-19. …”
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    Genomic epidemiology of SARS-CoV-2 in Esteio, Rio Grande do Sul, Brazil
  12. 8652
    “…Discussion  Rigor and evidence need to be taken into consideration when designing, implementing, and using digital tools to combat COVID-19 to avoid delays and unforeseen negative consequences. It is paramount to employ a multidisciplinary approach for the development and implementation of digital health tools that have been rapidly deployed in response to the pandemic bearing in mind human factors, ethics, data privacy, and the diversity of context at the local, national, and international levels. …”
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    Evidence-Based Health Informatics as the Foundation for the COVID-19 Response: A Joint Call for Action
  13. 8653
    “…These findings would be of paramount importance in planning and devising effective prevention and intervention strategies in Bangladesh as well as other countries with similar sociocultural setting.…”
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    The parental perspective of thalassaemia in Bangladesh: lack of knowledge, regret, and barriers
  14. 8654
    “…The genetic correlations among whole weight, meat yield, and body shape traits were favorably positive, suggesting that the selection for whole weight would have beneficial effects on meat yield and body shape traits. Of paramount importance is the fact that the genomic prediction showed moderate to high accuracy for the traits studied (0.38–0.92). …”
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    Genomic Prediction for Whole Weight, Body Shape, Meat Yield, and Color Traits in the Portuguese Oyster Crassostrea angulata
  15. 8655
    “…Future study focusing on prevention of venous thromboembolism in this population is paramount to improve patient-oriented outcomes given the high morbidity and mortality of venous thromboembolism and the significant impact it has on transplant candidacy.…”
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    Plasminogen activator inhibitor is significantly elevated in liver transplant recipients with decompensated NASH cirrhosis
  16. 8656
    “…CONCLUSIONS: Stroke rehabilitation is a unique healthcare context where patient activity, practice and motivation are paramount. We found many evidence gaps that with more targeted research could better inform the design of rehabilitation spaces to optimise care. …”
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    Built environments for inpatient stroke rehabilitation services and care: a systematic literature review
  17. 8657
    “…A prompt and accurate risk stratification tool for chest pain patients is paramount to help physcian effectively progrnosticate outcomes. …”
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    30 day predicted outcome in undifferentiated chest pain: multicenter validation of the HEART score in Tunisian population
  18. 8658
    “…Therefore, highly specific diagnostic tools are paramount when used to measure low thresholds. The TPP process brought to the forefront the importance of linking use case, program platform and diagnostic performance characteristics when defining required criteria for diagnostic tools.…”
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    Diagnostics to support elimination of lymphatic filariasis—Development of two target product profiles
  19. 8659
    “…Treatment is essentially supportive; role of antiviral agents is yet to be established. It is paramount to implement infection control practices by infection source controlling, transmission route blocking, and susceptible population protection. …”
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    Coronavirus disease-2019 and its current scenario – A review
  20. 8660
    por Somefun, O., Constant, D., Endler, M.
    Publicado 2021
    “…Convenience, protection from pregnancy and privacy issues were paramount and women expressed preference for engagement with staff who knew their abortion history, and with whom they had an established connection. …”
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    Immediate IUD insertion after second trimester abortion: implications for service delivery
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