“…Continuous capacity building of AMR surveillance sites through mentorships to improve quality of data generated is of paramount importance. E. coli and S. aureus were the most frequently isolated pathogens. …”
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“…Several studies conducted in Sertoli cell-specific pRB-KO mice have demonstrated that pRB-mediated inhibition of E2F3 is essential for Sertoli cell functional maturation and cell cycle exit, highlighting that RB-E2F interaction in Sertoli cells is paramount to male fertility. Similarly, ablation of either pRB or E2F1 in the germline results in progressive testicular atrophy due to germline stem cell (GSC) depletion, emphasizing the importance of proper RB-E2F interplay for germline maintenance and lifelong sperm production. …”
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“…CONCLUSIONS: Emphasising non-pharmacological interventions for T2DM prevention can improve health outcomes and lessen the economic burdens, which will be of paramount importance in LMICs. SYSTEMATIC REVIEW REGISTRATION NUMBER: CRD42020191507…”
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“…OBJECTIVES: Despite ongoing disagreement among the obesity research community, we have seemed to arrive at a paramount conclusion: there is no one-size-fits-all approach for weight loss. …”
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“…The prospective of the FET technique as a single-step treatment for aortic dissection seems low and follow-up in dedicated aortic centers is therefore paramount.…”
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“…A multidisciplinary approach and the application of the proposed algorithm is of paramount importance to optimize the outcomes of these patients.…”
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“…The selection of the dressing is of paramount importance as inappropriate wound management and dressing selection can delay the wound healing process. …”
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“…These data have implicitly demonstrated that RUNX1 mutations are critical in the pathogenesis of various hematological malignancies, and further investigations into the role of RUNX1 are paramount for the development of new cancer treatments.…”
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“…Therefore, reducing the duration of milking operations without harming the cows is paramount. This study aimed to test the variation in different parameters of milking operations on non-automatic milking machines to evaluate their effect on a herd and finally reduce the milking time. …”
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“…Integration of results obtained from these varied testing platforms with patient outcomes remains paramount for future studies.…”
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“…Hence, the analysis of hurdles is paramount. Given the initial focus of PrEP provision among men-who-have-sex-with-men (MSM) via a demonstration project that was launched in June 2015, AmPrEP in Amsterdam, and pharmacies in the main urban areas (so called “Randstad”, entailing Amsterdam, Utrecht, Leiden, The Hague and Rotterdam), investigating regional differences is necessary. …”
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“…To (governmental) decision makers, IP challenges might not appear to be of paramount urgency compared to the many undoubtedly huge operational challenges to deploy critical resources. …”
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“…Thus, having confidence in the measurements of primary tumors is paramount. We aimed to quantify the degree of tumor tissue shrinkage after 24 and 48 h of formalin fixation to guide clinicians in their use of post-fixation measurements. …”
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“…Staff well-being was found to be paramount, however supporting staff was found to be challenging due to national constraints placed upon IAPT and the targets the service is asked to achieve. …”
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“…Furthermore, communication of medication changes was reviewed in the context of the paramount importance of collaborative decision-making in aiding adherence. …”
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“…AIMS: In view of the limited number of acute inpatient beds relative to demand in England, a thorough assessment prior to referral is paramount in ascertaining clinical need. A comprehensive risk assessment is crucial in light of patient safety and assessing risk to others. …”
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“…BACKGROUND: The timing of initiation of first antenatal care visit is paramount for ensuring optimal care and health outcomes for women and children. …”
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“…The ribosomal protein uL11 is located at the basis of the ribosome P-stalk and plays a paramount role in translational efficiency. In addition, no mutant for uL11 is available suggesting that this gene is haplo-insufficient as many other Ribosomal Protein Genes (RPGs). …”
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“…Improved sanitation at the abattoirs, use of personal protective equipment by animal handlers, vaccination of animals against brucellosis, and ranching of animals to curb the spread of the disease should be paramount to all stakeholders. ABSTRACT: The global burden of human and animal brucellosis remains enormous. …”
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“…Identifying the determinant factors of IPV among pregnant women is of paramount importance to overcome its negative consequences thereby increasing the performance of women in all activities. …”
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