“…SIMPLE SUMMARY: Given that younger women with endometrial carcinoma (EMCA)/endometrial hyperplasia (EH) tend to have better prognoses than older women and fertility-sparing treatment continues to be recognized as acceptable management, the importance of understanding pregnancy outcomes in this cohort is paramount in order to provide better and more informed family planning counseling. …”
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“…Likewise, the involvement of patient/public contribution was paramount in study design and overall development of our study team.…”
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“…CONTEXT: The resection technique used to excise tumor during robotic partial nephrectomy (RPN) is of paramount importance in achieving optimal clinical outcomes. …”
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“…These tools could potentially provide temporal and clinical characteristics and are thus paramount in developing-countries lacking sufficient ongoing COVID-19 epidemic descriptions. …”
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“…Antimicrobial stewardship (AMS) is part of the WHO global strategy on antimicrobial resistance,(3) and shortening the length of time a patient is treated with unnecessarily broad-spectrum agents is paramount. Our aim was to review whether the Reveal rapid AST system (bioMérieux) shortened time-to-best-fit antibiotic, and whether this was a spectrum escalation or de-escalation, in Gram-negative bacteraemias in Sheffield Teaching Hospitals NHS Trust. …”
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“…While efforts to reduce public stigma are paramount, change can be slow, and interventions to prevent internalised stigma may also be needed. …”
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“…PPARγ has a close association with lipid metabolism and displays high expression in adipose tissues. It is of paramount importance to control lipid metabolism to regulate PPARγ expression and activity in pigs. …”
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“…Due to the tight association between virus transmission, blood feeding, and egg development, understanding midge physiology is paramount to limiting pathogen transmission. Previous studies have demonstrated the importance of small non-coding RNAs (ncRNAs), specifically microRNAs (miRNAs), in multiple aspects of vector physiology. …”
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“…BACKGROUND: Living donor liver transplantation (LDLT) has revolutionized the field of transplantation without compromising donor safety. Donor safety is of paramount concern to the transplant team. BMI >35 kg/m(2) is mostly considered a contraindication to liver donation. …”
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“…INTRODUCTION: Estimating the current likelihood of transitioning from a clinical high risk for psychosis (CHR-P) to psychosis holds paramount importance for preventive care and applied research. …”
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“…Subtherapeutic dosing is highly likely to result in the selection of a resistant clone; thus, it is of paramount importance to ensure the imatinib dose is sufficient. …”
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“…Quick and precise assessment bears paramount importance in deciding life-saving and definitive management. …”
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“…Last but not least, the effect of the research opens the unique opportunity to evaluate the prioritization outcome obtained within the process of consistent PCs from the well-known perspective of statistical hypothesis testing i.e. the probability designation of the chance that accepted ranking results which were considered as correct due to low probability of change may be incorrect, hence they should be rejected, and the probability designation of the chance that rejected ranking results which were considered as incorrect due to high probability of change may be correct and should be accepted. The paramount finding of the research is the fact that consistent PCMs provide PVs, which elements cannot be considered as established, but only approximated within certain confidence intervals estimated with a certain level of probability. …”
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“…CONCLUSIONS: Understanding whether an intervention is needed in a particular situation is just the start; designing an intervention so that it is used within that situation is paramount. This co-design process engages end users to create a GUI that includes the aesthetic and functional details they need in a manner that aligns with their existing work practices. …”
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“…INTRODUCTION: Complete surgical tumor resection is paramount in the management of soft tissue sarcoma (STS) in humans, dogs, and cats alike. …”
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“…Because fluconazole is the most widely used antifungal agent in most regions with outbreaks, it is paramount to restore its antifungal activity. Milbemycin oxim (MOX), a well-known canine endectocide, is a potent efflux pump inhibitor that significantly potentiates the activity of fluconazole against FLZR C. glabrata and C. albicans. …”
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“…Thus, searching for laboratory biomarkers of angioinvasion is of paramount importance.In this study, the potential screening utility of oxidative stress-related markers, such as total oxidative capacity (TOC), total antioxidant capacity (TAC) and 8-OHdG was assessed to identify angioinvasion in PTC patients.For the purpose od this study, 50 patients diagnosed with angioinvasive PTC (study group) and 50 patients with very low risk PTC (control group) were enrolled. …”
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“…Conclusions: The completion of 2 doses of government-approved COVID-19 vaccination is paramount in preventing severe COVID-19 disease and death. …”
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“…The molecular phenomenon of DAA resistance is paramount in the development of HCV drug candidates. …”
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“…Conclusions: Proper disinfection and using appropriate 3D-printed materials are essential to limiting bacterial contamination. 3D printers and their products can be invaluable for hospitals, especially when supplies are low and healthcare worker safety is paramount. Environmental services should be made aware of the presence of antimicrobial 3D-printed materials, and patients should be discouraged from printing their own items for use in hospital environments. …”
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